Zilxi to launch at $485 for 30gm canister

The publicity around the launch for Zilxi, the new 1.5% topical minocycline based treatment for rosacea contains confirmation that the list price for a 30gm prescription will be $485.

Now known as VYNE Therapeutics, the makers of Zilxi are preparing to make their recently FDA approved treatment for the papules and pustules of rosacea available widely.

Zilxi Press Release

VYNE Therapeutics Announces ZILXI (minocycline) topical foam, 1.5% Available in Pharmacies Nationwide on October 1st

ZILXI is the First FDA Approved Minocycline Product for the Treatment of Inflammatory Lesions of Rosacea in Adults

ZILXI Offers Efficacy with Low Systemic Absorption

BRIDGEWATER, N.J., Oct. 1, 2020 /PRNewswire/ — VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE” or the “Company”) today announced that its novel ZILXI™ (minocycline) topical foam, 1.5% will be available on October 1, 2020 by prescription for the treatment of inflammatory lesions of rosacea in adults. Approved by the U.S. Food and Drug Administration (FDA) in May 2020, ZILXI is the first minocycline product of any form to be approved by the FDA for use in rosacea, a diverse skin condition that most commonly presents with symptoms such as deep facial redness, spider veins (telangiectasia) and acne-like inflammatory lesions (papules and pustules). This new once-daily therapy will be available in retail, community and specialty pharmacies nationwide.

“By combining a unique topical delivery system for minocycline with strong efficacy and tolerability, ZILXI is positioned to address a very challenging skin condition in a way that could change treatment considerations for rosacea.”

The Company also announced that the annual list price of ZILXI will be $485 per 30-gram canister, in parity with the wholesale price of AMZEEQ (minocycline) topical foam, 4%, the Company’s topical minocycline indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in adults and pediatric patients 9 years of age and older. 

Why are Rosacea Prescriptions so Expensive?

Whilst it is good news that a new rosacea treatment is becoming available, the full list price will no doubt exclude many rosacea sufferers, most especially those without full insurance cover.

There are many rosacea sufferers posting here how much their Rosacea prescriptions cost, it makes for sobering reading. Zilxi looks set to continue the trend of very expensive rosacea prescription prices.

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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5 Reader Comments

  1. Comment via email.

    “This price is ridiculously high! I am 72 y/o. I guess I’ll continue to live with it!
    Thank you for all of your information.”

  2. Hoan says:

    $485 ????? For Christ Sake you guys….

  3. Boca Rehab says:

    I was prescribed minocycline last year in combination with adapalene, used it for about 7 months it cleared up my skin really well, but when I stopped my acne came back worse and the antibiotics ruined my gut health. My doctor wasn’t very clear on how long I was supposed to be on it and didn’t tell me the risks mentioned. And I want to start taking Zilxi, does Zilxi have such side effects?

  4. Marc.truesdale says:

    Does anyone know when or if Zilxi will be available in the U.K
    Thanks in advance Marc

  5. NK says:

    I’m in the USA. Started using this about 5 months ago. Works great for me. I’m in my 60’s. Without the redness and bumps my sister said my face looks 10 yrs younger! I use about a pea size portion about 6 nights/week. It’s a bit greasy feeling. First got samples from my Dermatologist to see if it works. She pointed me to a small pharmacy that applied all manufacturers and any other “coupons” that could be applied. My price came to only $75. For me it lasts a long time and if I only have to fill it at that price 2-3xs/yr it’s worth it. I don’t take any antibiotics as I believe they made me gain pounds. So far this is the best “prescription” I’ve ever used for my Rosacea! I’ve had no side effects either.

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