Will RHOFADE work for me ?

So RHOFADE has been approved by the FDA and will be available in the United States from May 2017. What does the published trial data suggest about the likelihood of RHOFADE being a winning treatment for your red face?Two clinical trials comparing RHOFADE to an inactive gel produced similar results, so rosacea sufferers can have some confidence that the level of success of their usage of RHOFADE will match this data.

What does `RHOFADE works’ mean ?

An easily measurable criteria is needed so that all trial participants can give a clear indication of whether RHOFADE worked for them or not. For the 2 clinical trials referenced,  in order to decide that the product was working, trialists needed to see a 2-grade improvement in their redness. This improvement was seen in both the clinician’s and the subject’s assessment of their facial redness.

Will RHOFADE work for me?

Going on the published clinical data, basically one in 6 or 7 users of RHOFADE will have a 2-grade improvement in their facial redness, typically for 12 hours, and continuing for 29 once-daily uses.

What is a 2-grade Erythema Reduction?

The Clincian’s Erythema Assessment (CEA) is a 5 grade assessment that is generally considered a reliable instrument for the redness of rosacea. The 5 grades are ;

  • 0 = none,
  • 1 = mild,
  • 2 = moderate,
  • 3 = significant,
  • 4 = severe

So you can see that your facial redness should have a significant improvement to move up 2 grades on the CEA scale.

Are you convinced?

What do you think, are you willing to give RHOFADE a try?

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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15 Reader Comments

  1. Andy says:

    Everyone’s waiting for the R word, i.e. Rebound redness. Does it go back to your original state or make things worse is what we need to know

  2. sallyann says:

    Yep. Is it any different from Mirvaso? My issue is only the flushing component of rosacea and ive always been too scared to try Mirvaso incase of rebound flushing making my condition worse long term.

  3. George bidwell says:

    One in 6 or 7 people are likely to see improvement?? Looks like it’s set to be almost as much of an impressive waist of everyone’s time as mirvaso was!!

  4. Scarlet Red says:

    I agree. It’s the big elephant in the room, given how this drug should work in a somewhat similar fashion as Mirvaso, yet why isn’t it even mentioned in the trial data? Worrying.

  5. Mike says:

    One in 6 or 7 people? That’s an incredibly ineffective medication. That’s almost unbelievably bad. It should be 4-6 out of 7 to even be taken seriously. One out of 7? Unbelievable

  6. Edward says:

    Tried a sample. Got rebound. Doesn’t work

  7. Vicki says:

    My derm gave me some Rhofade samples, and it’s working well so far. But it’s a moot point because it will cost $500.00 per tube. Not too surprising for a new drug. Can’t afford it.

    • Rugh says:

      Received sample tube today from dermatologist and info for purchase from St Peters Community Pharmacy. Talked with pharmacy and their cost is $75 per tube and they ship to your home.(636)244.5385 is their contact number.

  8. Maryanne Wallace says:

    Will rhofade work for I’m a 52 year old female tried Soolantra and didn’t work

  9. Margcita says:

    I see in the info on the web that it lasts “up to 29 days.”. Does that mean that after a month of daily use the product will stop working?

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