An in-depth article to do with the effect of VEGF on the vasodilation and vasorelaxation of blood vessels.
Vasodilator effect and mechanism of action of vascular endothelial growth factor in skin vasculature
American Journal of Physiology Heart and Circulatory Physiology 286: H946-H954, 2004.
Abstract: Various laboratories have reported that local subcutaneous or subdermal injection of VEGF165 at the time of surgery effectively attenuated ischemic necrosis in rat skin flaps, but the mechanism was not studied and enhanced angiogenesis was implicated. In the present study, we used the clinically relevant isolated perfused 6 x 16-cm pig buttock skin flap model to 1) test our hypothesis that VEGF165 is a potent vasodilator and acute VEGF165 treatment increases skin perfusion; and 2) investigate the mechanism of VEGF165-induced skin vasorelaxation.
VEGF can be found in TNS Recovery Complex made by SkinMedica. This product has shown to reduce facial redness.