Treating Rosacea with Collagen (Matricol)

Written by on June 28, 2012 in patents with 4 Comments

Matricol, which is freeze dried sheets of collagen, is another example of a hopeful rosacea treatment emerging in a patent application.

This time a health care company in Germany is patenting the use of collagen as a treatment for skin diseases including rosacea.

The assignee is Dr. Suwelack Skin & Health Care AG in Billerbeck, Germany. Suwelack are the makers of Matricol, the product mentioned as an example in the patent application. We are told that Matricol uses a “special freeze-drying process that ensures the preservation of the nativity of the collagen, i.e. its original character and biological activity.”

Collagen For Use in the Treatment of Skin Diseases

USPTO Applicaton #: 2012/0141575

Pub Date: Jun. 7, 2012

Agent: Dr. Suwelack Skin & Health Care Ag – Billerbeck, DE
Inventors: Anja Kassner, Martin Trautmann, Sabine Gütt

The present invention relates to collagen for use in the treatment of inflammatory and degenerative skin diseases and damage to the skin connected therewith, such as in particular in the treatment of psoriasis, dermatitis, neurodermitis, rosacea, urticaria (hives), pruritus (itching), skin eczema and actinic keratosis. In particular, the invention relates to freeze-dried collagen in the form of layered dressings, sheets, pads or masks for the aforementioned use.

Example 2

Use of Freeze-Dried Layered Collagen Matrices in the Treatment of Rosacea

The treatment took place within the context of a clinical trial (study/observation of application) by means of commercially available layered freeze-dried collagen preparations of the brand Matricol with a collagen content >90% by wt.

Within the context of the trial, 10, patients aged between 24 and 79 years with slight intensity (rosacea diathesis and rosacea erythematosa-teleangiectatica) or severe intensity (rosacea papulopusfulosa) rosacea each carried out up to 6 individual observations of application.

In total 41 individual applications were carried out by the 10 patients, with 4 cases of application in which patients did not document the result after 24 hours.

For this purpose, patients assessed the following parameters about 15 minutes after application of matricol as well as 24 hours after the treatment, in each case compared to the time prior to the application on the respective day of application. Furthermore, a corresponding assessment of the parameters was carried out by the test physician approx. 15 minutes subsequent to the application of Matricol.

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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4 Reader Comments

  1. james says:

    My rosacea flares up, ( my neck, checks, froehead, and then my entire face turns deep red), when my face gets warm. Warmth from the sun being out doors , even in shade if the temperature is higher than 85 degrees. Warm temperature in a room, a car, etc. …………

    I use metrogel, finaca, take antiinflamatories, always use a sun block, aloe vera I also use, and once a day 40 mg oracea. I Don’t use caffaine, consume spicy food, smoke, or use alcohol. Any suggestions that I can do to help my face not flaring up, turning red?


  2. Christian Honey says:

    Hi there,

    I highly reccommend Aloe Vera Gel. Make sure its pure (>95%) Aloe Vera . It helped me massively withe the redness. What was a real breakthrough though was a cream against mites (Lyclear in the UK). It is usually used for lice but the most promising study comparing Metrogel and Permethrin (Lyclear) used the dosis of Permetrhin in Lyclear (5%). My symptoms are almost totally gone after a month of using Lyclear (I followed the treatment regimen of the trial).

    Hope that helps you too.



  3. jolo says:

    Here’s some helpful information: When you are really reddened:
    Splash Cool water to the face for a couple minutes and pat dry. Take by mouth 25mg. Benedryl, no rubbing face—when skin flares up, follow that regimen. If staying home, use 50 mg. Benedryl. It can make you a bit sleepy. This is an over the counter antihistimine. Cheap too.
    Eat foods such as cantaloupe, salmon, almonds, oatmeal, apples, pears. Limit tomato sauce.
    Fish oil tablets by mouth help.
    Always very gently cleanse your skin.
    For years I used Estee Lauder skin products and more recently purchased the Clarisonic Mia device for skin care.

    Consult the web for Dr. Nicholas Perricone diet.
    He’s a dermatologist, famous, who has skin care products as well.

  4. Billy says:

    It’s a real bummer. My skin therapist recommended a daywear cream which is excellent – soothing and disguising. It’s Invisible Zinc, which is also a moisturiser and sunscreen. Zinc is very good, soothing. It’s a natural product. It’s also a little tinted, which means it helps to disguise the problem. I use it all the time, even though I’m a bloke. Secret is to apply evenly, wait about 10 mins, and then rub in well again, to remove any shine or sign you are wearing it.
    Hope it helps, and good luck, Billy

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