spironolactone vs. accutane

Written by on February 26, 2008 with 0 Comments

From:  “Linda Sy MD” 
Date:  Wed Aug 11, 1999  8:50 am
Subject: spironolactone vs. accutane


There is hypertrophy (as seen in rhynophyma) as well as hyper-activity of sebaceous glands in rosacea patients. Regardless of the cause, we do know that rosacea patients frequently respond favorably to similar treatments as those given to acne patients. Rosaceans whose acne lesions are unresponsive to different oral antibiotics, do well with low dose accutane rx. My experience with treating rosacea with Spironolactone is limited. I have had a lot of experience with Accutane and good results with it. If your dermatologist placed you on Spironolactone, then you should have faith that she/he is making a good judgment based on your particular case. If you have doubts, then you really should confront your misgivings with your doctor and together, you can both come to a decision. This group is a great and helpful source of info but everyone is different and sometimes too much anecdotal data can be confusing. 

Linda Sy M.D.
Linda Sy Skin Care
Voice:Toll-free 877-Lindasy (546-3279)
FAX: 925-939-5207

—–Original Message—–

From: Mary Bromage
To: rosacea-support@_.com>
Date: Tuesday, August 10, 1999 1:34 PM
Subject: [rosacea] Question for Dr. Sy / reason for the bumps

I am a bit confused about the cause of the breakouts that I am getting.  I thought that all breakouts were caused by overactive sebaceous glands, but there has been discussion that the bumps caused by rosacea are not caused by overactive sebaceous glands. If this is true than medication that helps tame the overactive sebaceous glands will not help. I have currently been prescribed spironolactone and now I am thinking that it will not help because it lowers androgens in the skin. If this is not the reason for the breakouts than it will not work. I have heard that seb/dermatitis is caused by overactive sebaceous glands and I have this but I don’t know about the rosacea. I would appreciate any feedback from you and others one this issue. I am very confused.


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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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