I was alerted to the launch of a product called Promiseb by a comment left on the Sebclair for Seborrheic Dermatitis post. Since then the news web sites are also covering the press release. Promiseb (probably pronounced Promi-seb) is launching in the U.S. via Promius Pharma, after being licensed from Sinclair Pharma in 2007.
Promiseb Topical Cream (Sebclair) is a non-steroidal, prescription only cream for the treatment of seborrheic dermatitis. It has demonstrated anti-inflammatory and anti-fungal properties. Sebclair is approved for use in the European Union to treat seborrheic dermatitis. One of Sebclair’s (and now Promiseb’s) claims to fame is that it contains no corticosteroids or immunomodulating agents.
Promiseb is claimed to “Significantly reduced Malassezia yeasts, the organisms that may cause seborrheic dermatitis, by 94%”. These claims are more interesting when you consider the ongoing discussions like Malassezia Globosa causes seborrhea, Pyrithione Zinc is effective, Could M. Globosa Cause Rosacea? and Real cause of seborrhea discovered!.
For a description of the ingredients and suggested method of action see Sebclair for seborrheic dermatitis.
From the press release: Sebclair launched in the US by Dr Reddy’s Laboratories’ subsidiary Promius Pharma, LLC
Jeff Wasserstein, President of Promius Pharma, said “We are very excited about Promiseb Cream because it has the potential to replace both anti-inflammatoryand antifungal treatments in patients with seborrheic dermatitis. In a clinicalstudy Promiseb was shown to have efficacy comparable to desonide cream 0.05% atdays 14 and 28 with fewer relapses.
“Promiseb Cream also has an excellent safety profile with no restrictions onage, duration of use or application on the face.” He continued, “We are very enthusiastic about this product because our clinical research shows thatPromiseb Cream may be used as a first-line treatment for seborrheic flares andfor long-term maintenance”
No Active Ingredients?
What is the active ingredient in Promiseb Cream?
Promiseb Cream is a prescription-only, nonsteroidal FDA-cleared medical device and has no active ingredient. However, Promiseb Cream has demonstrated both anti-inflammatory and antifungal properties.
The makers of Promiseb do say that those who are allergic to shea butter or shea nut oil should not use their product though.
It does seem to be an unusual situation; a prescription only medicine that claims to have no active ingredients.
Here is the full list of ingredients as detailed in the Promiseb Prescribing Information.
Purified Water, Isohexadecane, Butyrospermum parkii, Pentylene glycol, Ethylhexyl palmitate, Cera alba, PEG-30 Dipolyhydroxystearate, Bisabolol, Polyglyceryl-6 polyricinoleate, Tocopheryl acetate, Hydrogenated castor oil, Acifructol complex, Butylene glycol, Magnesium sulfate, Piroctone olamine, Allantoin, Magnesium stearate, Disodium EDTA, Vitis vinifera, Ascorbyl tetraisopalmitate, Glycyrrhetinic acid, Propyl gallate, and Telmesteine.
Auburn-NH has posted an early review of Promiseb, from using a doctor supplied sample.
Promiseb is offering a 50% discount off your co-pay or $40, whichever is less. For more information see Promiseb Savings Coupon.