retinaldehyde may reduce VEGF

Written by on August 18, 2005 in research, VEGF with 1 Comment

From Skin and Allergy News, July 2005, Think Outside the Box for Rosacea Tx Options.

Cherie Detrie, M.D., director of cosmetic dermatology at the University of Pennsylvania in Radnor, said

“the retinaldehyde offers rosacea patients who may have sensitive skin the benefits of retinoids with fewer side effects.”

She described the formulation as a “way station” between retinol and retinoic acid.

“Research demonstrates that retinaldehyde, like retinoic acid, produces dose-dependent epidermal thickening, reduction of the stratum corneum, and increased keratinocyte turnover. Importantly for rosacea, it may also reduce vascular endothelial growth factor (VEGF), which has neoangiogenic and inflammatory properties in the skin.”

Retinaldehyde is made by Pierre Fabre Dermo-Cosmetique, which sponsored Dr. Detrie’s talk.

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About the Author

About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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1 Reader Comment

  1. D.Price says:

    In reference to the article above, I would like to see more research of retinaldehyde to see if it does or does not reduce VEGF… as the article says it “may reduce VEGF”.

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