Redless Specific Serum from Integral Dermo Correction

Written by on September 5, 2012 in Red Face of Rosacea, research, Rosacea Topicals with 2 Comments


A just published paper alludes to a new redness reducing cosmeceutical.

The product is referred to as 100RXED2025, but it looks likely that the actual product name is the multi syllabic mouthful “Integral Dermo Correction Redless Anti-Redness Facial Serum”. In other publicity it is also called Redless Specific Serum.

The product claims to be comprised of 40% of active ingredients, including a photochromatic pigment, called photolite PKS to provide a concealing effect – an ingredient “that adjusts to surrounding light”. Sounds a bit like something a spy would use …

18 Claimed Active Ingredients

18 active ingredients: Aldavine, APT, coenzyme Q10, esculoside, extrait decorce de saule, HomeoAge, HomeoSoothe, Homeo-Shield, lipochroman, matrixyl 3000, neutrazen, photolite PKS, retinol, Regu Age, skin influx, sodium DNA, thymulen, trylagen

The formulation is also said to contain another group of ingredients called Regen-16: Abyssine, hyaluronic acid, bisabolol, creatine, EUK-134, flavagrum, glycerin, LNST, moist 24, MRT EX, Net DG, 330 Regederme, sepilift, squalene, tyrostat, vitamin E.

Published Research Good Start

Many cosmeceuticals go straight to their creative marketing claims with little published research to back up their grand claims. The fact that IDC has been able to get a paper published with some demonstrable results is a good start for this potential new product.

Here is the abstract.

Clinical efficacy of a serum integrating multiple cosmetic ingredients in the management of erythema of the face in aging skin.

J Cosmet Dermatol. 2012 Sep;11(3):207-12.

Dupont E, Léveillé C, Gomez J, Loigeret M, Loing E, Bilodeau D.

Immanence Integral Dermo Correction, Quebec, Quebec, Canada The Plastic Surgery Clinic of Metropolitan Quebec, Quebec, Canada Spin Control North America, Montreal, Quebec, Canada Lucas Meyer Cosmetics, Quebec, Quebec, Canada.

Background: Skin redness is a common cosmetic concern affecting predominantly fair-skin individuals and often leading to rosacea.

On the basis of the current scientific knowledge of the physiological mechanisms underlying the problem, a complex and integral skin care serum (100RXED2025) was developed and tested clinically for efficacy.

Method: Forty-five healthy men and women volunteers, age 30-65, were recruited.

All subjects had fair skin (phototype I, II, or III) and presented some degree of skin redness with telangiectasia on the cheeks, the nose, or the nose sides, at baseline.

In the course of this open label study, subjects applied the test product on their face, twice daily for 56 days.

For each subject, skin redness was evaluated through colorimetric and visual analysis of photographs taken under cross-polarized light at T = 28 (week 4) and T = 56 (week 8), then compared to baseline measurements obtained at day 0.

Results: Forty-four volunteers completed the study.

On visual evaluation, skin redness had decreased in average by 32.2% at T = 28 (P < 0.001) and by 48.0% at T = 56 (P < 0.001).

Importantly, 91% of the subjects showed improvement of skin redness at T = 28, reaching 100% at T = 56.

Colorimetric analysis gave an average reduction in redness of 11.6% at T = 28 (P < 0.001) and 13.7% at T = 56 (P < 0.001).

Conclusion: The anti-redness efficacy of the test product was demonstrated after 28 days with further increase following 56 days of application.

Benefit Takes a Long Time

Whilst the results show everyone did enjoy some reduction in redness, the quantitative measure using a Colorimeter  showed a modest improvement in redness after a month rising slightly after 2 months.

This may be a good thing in that it likely won’t produce a rebound redness, but does mean that you need to keep using the product for many weeks. One does have to wonder how long a 15ml bottle will last especially for a large area over several months duration.

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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2 Reader Comments

  1. Coleen Brock says:

    check your dictionary. I don’t think you meant “eludes.”

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