This paper offers a review of the published research relating to the use of polyphenols to treat rosacea symptoms. The papers’ authors undertook a literature review to find which members of the polyphenol family offer proven efficacy when treating rosacea symptoms.
Polyphenols comprise a very large number of compounds – for eg. their members can be found in green tea, ginger, red wine, olives, blackcurrants and many more. Thus it can be quite a task to properly answer the question of which polyphenols are best suited to offering treatment options to rosacea sufferers.
At best, the published research was found to only able to confirm that polyphenols may offer some relief for the redness and papules and pustules of rosacea. Like many of these sorts of papers, they end with the slightly frustrating conclusion that `more research is needed’.
The Journal of Alternative and Complementary Medicine. June 2017, ahead of print
Objectives: Various treatment options are available for the management of rosacea symptoms such as facial erythema, telangiectasia, papules and pustules, burning, stinging, and itching. Botanical therapies are commonly used to treat the symptoms. The objective of this review is to evaluate the use of polyphenols in rosacea treatment.
Design: PubMed, Embase, Biosis, Web of Knowledge, and Scopus databases were systematically searched for clinical studies evaluating polyphenols in the management of rosacea.
Results: Of 814 citations, 6 met the inclusion criteria. The studies evaluated licochalcone (n = 2), silymarin (n = 2), Crysanthellum indicum extract (n = 1), and quassia extract (n = 1). The studies only evaluated topical formations of stated polyphenols. Main results were summarized.
Conclusions: There is evidence that polyphenols may be beneficial for the treatment of rosacea symptoms.
Polyphenols appear to be most effective at reducing facial erythema and papule and pustule counts.
However, studies included have significant methodological limitations and therefore large-scale, randomized, placebo-controlled trials are warranted to further assess the efficacy and safety of polyphenols in the treatment of rosacea.
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