Their has been much talk lately about using alpha adrenoceptor agonists as rosacea treatments because they show vasoconstrictor actions. Some examples are brimonidine, oxymetazoline, naphazoline, and others.

There are quite a few patents out there discussing these, and even testing some of them. Some of these patents have been mentioned before on the site.

Here are links to some of these patents.

• US20040242588

Compounds, formulations, and methods for treating or preventing rosacea

• US20050020600

Methods of treating cutaneous flushing using selective alpha-2-adrenergic receptor agonists

• US20050165079

Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using a1-adrenoceptor agonists

• US20050276830

Compounds, formulations, and methods for treating or preventing inflammatory skin disorders

• US20060171974
  Compounds, formulations, and methods for treating or preventing rosacea