Mysterious PAC-14028 1% Cream for Red Face

Written by on February 10, 2014 in research with 5 Comments

An intriguing clinical trial has surfaced for a cream that is so far unknown to rosacea sufferers.

The makers of this cream, which is in Phase 2 trials, Amore Pacific Corporation is located in South Korea.

Amore Pacific makes impressively expensive cosmetics. I wonder if anyone has tried their premium products?

It is encouraging to see them subjecting one of their products to a clinical trial. So many companies want to make claims about how good their products are for rosacea, and the clinical trial path is one way we can know for sure.

Second reason that this could be a good trial is that it is targeting the redness, broken blood vessels and the papules and pustules of rosacea.

The study has completed, so if the results were promising we should expect to see more of this product as it develops.

Clinical Trial NCT02052999

Study to Evaluate the Efficacy and Safety of PAC-14028 Cream in Rosacea Patients

The objective of this study is to determine the efficacy and safety of PAC-14028 1% cream of Amorepacific Corporation in patients with erythema-telangiectatic or papulopustular rosacea

PAC-14028 cream 1% will be compared against the vehicle and rozex 0.75%.

Primary outcome: Change in Investigator Global Assessment (IGA)

Secondary Outcome Measures: Erythema severity, Telangiectasia severity, Inflammatory lesion counts
Enrollment: 80
Study Start Date: February 2013
Study Completion Date: August 2013

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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5 Reader Comments

  1. Davem81 says:

    David, do you have any idea on an approximate timescale for the publication of results after a trial has completed, generally speaking?

  2. Unfortunately you can’t say anything at all because companies can keep their results quiet for any period of time based on whether making them public helps them or not with their product development process.

    The only way we generally find out is if they issue a press release touting positive results.


  3. John A Betts says:

    The material in the Amorepacific trial is very likely to be the amino acid THEANINE.
    The company has a number of patent applications on uses for theanine including the treatment of acne – e.g. US20130137653

    I did post this previously but it somehow became lost in cyberspace.

  4. Juliette Kilpatrick says:

    Has anyone tried this company’s creams? Do they make any claims with their existing line?

    David. I really enjoy this site. So much information. Thank you.

  5. Nick says:

    Thanks Dave Im new on here lot to learn.

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