Mysterious L’Oreal Lotion Good for Redness (2012 AAD San Diego)

Written by on March 22, 2012 in Red Face of Rosacea, research, Rosacea Topicals with 3 Comments

At the recent AAD 2012 Annual Meeting in San Diego, a poster session sponsored by L’Oreal looked quite interesting. The session detailed some research on an un-named facial lotion. The research claimed a statistically significant improvement in redness after 4 weeks of use.

No searching could find a product from L’Oreal that contained the following ingredients;

  • palmitoyl tripeptide-8
  • epurea extract
  • bisabolol
  • caffeine
  • zinc gluconate

So it would appear that this is a new product under development from L’Oreal. This is potentially very good news for rosacea sufferers.

If you find the name of this product please let us all know in the comments below.

Rosacea sufferers will be aware that Rosacea heavyweight Galderma started life in 1981 as a joint venture between L’Oreal and Nestle.

Poster Session 5554

Clinical evaluation of the effectiveness and tolerance of a facial lotion on subjects with rosacea

American Academy of Dermatology 70th Annual Meeting, March 16–20, 2012, San Diego, California. Poster Abstracts, Supplement to JAAD, April 2012, Volume 66, Number 4.

Susana Raab, L’Oreal Research and Innovation, Clark, NJ, United States; Christian Oresajo, L’Oreal Research and Innovation, Clark, NJ, United States; Margarita Yatskayer, L’Oreal Research and Innovation, Clark, NJ, United States; Zoe Draelos, MD, Duke University School of Medicine, Durham, NC, United States

Background: Rosacea is a chronic skin condition involving inflammation of the cheeks, nose, chin, and forehead. It causes redness, flushing, and inflammatory papules. Subjects with rosacea have sensitive skin that is easily irritated by skin care products. There is a need for a topical product that reduces the signs and symptoms of rosacea without exacerbating the disease.

Methods: This study evaluates a facial lotion formulated with palmitoyl tripeptide-8, epurea extract, bisabolol, caffeine and zinc gluconate, in female volunteers with mild to moderate facial rosacea and the presence of a minimum of three inflammatory papules.

This clinical study included 50 female subjects between the ages of 25 and 60 with evaluations at baseline, postapplication, 2 weeks, 4 weeks, 8 weeks, and 12 weeks after product application.

For the duration of the study, volunteers used the facial lotion twice daily, and continued using any rosacea medications provided the type and dosage was stable for 3 months prior to study participation.

Evaluations were performed by a board-certified dermatologist and included objective and subjective tolerance grading, clinical efficacy grading of facial skin attributes for redness, flushing, smoothness, radiance, skin tone evenness, overall appearance, and rosacea severity using a 5-point ordinal scale.

Lesion counts, noninvasive bioinstrumentation to assess transepidermal water loss (TEWL), hydration and skin redness, subject self-assessment questionnaires, and digital photography were also included in the study.

Results: The results of this study showed significant improvements in redness, flushing, smoothness, radiance, overall appearance and
rosacea severity. The results showed a significant reduction in lesion count at all time points when compared to baseline.

There was a statistically significant drop in facial redness at week 4 and the TEWL measurements remained steady throughout the study demonstrating that the lotion is a gentle to the skin. Tolerance evaluations indicated the facial lotion was well tolerated by the study  panel.

Commercial support: 100% is sponsored by L’Oreal Research and Innovation.

Update September 2012

It seems that this product will be launched shortly by Skinceuticals, a division of L’Oreal. Watch the blog for more details.

Update 2014

This product is now available as Redness Neutralizer – see Skinceuticals Redness Neutralizer can help a red face

Related Articles

About the Author

About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

Follow Rosacea Support

Subscribe via RSS Feed Connect on Pinterest Connect on Google Plus

3 Reader Comments

  1. ALISHA says:

    THIS IS INTERESTING – I LIKE THE INGREDIENTS THEY ARE TRYING OUT IN COMBINATION – AND THAT THEY ALLOWED SUBJECTS TO REMAIN ON OTHER MED BUT MADE NOTE – BECAUSE IT MAYBE ONE OF THE COMBINATIONS THAT OTHERS WOULD HAVE SUCCESS WITH – FOR EXAMPLE NOW THAT I AM ON ORACEA – MY SKIN HAS ALLOWED ME TO USE LOTION AGAIN AND JOJOBA OIL FOR A CLEANSER – BEFORE ORACEA MY SKIN DIDN’T SEEM TO LIKE ANYTHING I DID! SO MAYBE THIS NEW LOTION PLUS ORACEA OR OTHER ORAL MED WOULD CAUSE THE OTHER TO WORK EVEN BETTER!

  2. Jasmine 215 says:

    Have you ever noticed that they continue coming up with MORE TOPICAL CREAMS and LOTIONS but no CURE? It’s the same old, same old!

    These pharmaceutical companies, their CEOs and investors, AND their biochemists must make out like BANDITS!

  3. Demelza says:

    Boycott L’oreal. They test on animals.

Leave your comment here

Top

Subscribe to Rosacea News

Enter your email address to receive the latest news about rosacea in your inbox.