Mirvaso Ingredients

Written by on August 27, 2013 in Mirvaso Gel (Brimonidine 0.33%) with 7 Comments


The just approved Mirvaso is a milestone in the long development and approval process. Rosacea sufferers have watched this drug since as early as 2004 when patents started emerging.

Now that Mirvaso has been officially approved by the FDA more information about the final formulation has emerged.

From the Mirvaso Prescribing Information we can see the final list of ingredients.

Active Ingredient

Brimonidine Tartrate Gel 0.33%; Each gram of gel contains 5 mg of brimonidine tartrate, equivalent to 3.3 mg of brimonidine free base.

The molecular formula of brimonidine tartrate is C11H10BrN5 • C4H6O6.

Chemically, brimonidine tatrate is 5-Bromo-6-(2-imidazolidinylideneamino) quinoxaline L-tartrate. Brimonidine tartrate has a molecular weight of 442.24
and appears as white to slightly yellowish powder

Inactive Ingredients

  • carbomer homopolymer type B (Carbomer is a generic name of Carbopol®, a trademarked product from Lubrizol, a gelling agent)
  • glycerin (moisturizer)
  • methylparaben (used primarily for their bactericidal and fungicidal properties i.e. a preservative to stop it going off)
  • phenoxyethanol (also a preservative)
  • propylene glycol (skin penetrating agent)
  • purified water
  • sodium hydroxide (carrier to get pH between 5-7.5)
  • titanium dioxide (protective agent)

Galderma claim through a related patent that this formulation comprises a “topical gel compositions containing carbomer and methylparaben that are substantially free of paraben crystalline particles and meet the antimicrobial requirement over an extended period of storage.”

You will note that this list of ingredients very closely matches the list of Sansrosa Ingredients as discussed by Rosacea News in March 2009. See that post for the percentage composition of each item.

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About the Author

About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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7 Reader Comments

  1. Jayne says:

    anyone know if Mirvaso is/could be helpful for Rhinophyma?

  2. Hi Jayne,

    I doubt that it will be able to help Rhinophyma in any meaningful way. With flushing maybe, with permanent redness yes, but rhinophyma I don’t think so.


  3. th_ says:

    hey david you know when will this be available on europe?or if i would order it online or something??i really wanna get it as fast as possible !

  4. There is no information available about the European availability of Mirvaso, sorry.

    Galderma are advanced in their approval application process and no doubt the approval by the FDA will help their cause, but one can only speculate about how long things will take.

    Being able to order Mirvaso online is just not going to happen. At this stage you will have to have access to a doctor in the US who can prescribe it for you. There won’t be any other way to get hold of it until it is approved in more countries.

  5. Barbara Alves says:

    Miravoso is available on Script only but i bought it in Portugal for about 40 euro I saw a dermatologist for 50 Euro but in London it costs £300 just to see a Dermatologist and the script costs more and you need a Doctore letter of referral to see a consultant so tskes a lot of time

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