Mirvaso – Frequently Asked Questions

mirvaso-gel

Surprise news today that Mirvaso, the product formerly known as Sansrosa, CD07805/47 and Col-118 has been granted approval by the FDA.

Here are some of the things we already know about Mirvaso ;

  • The prescription gel will be 0.33% brimonidine (this means each gram of the gel contains 5mg of birmonidine tartrate, which is the equivalent of 3.3mg of brimonidine)
  • The tagline for Mirvaso is that it “works quickly and lasts up to 12 hours”
  • Mirvaso is officially only for the persistent (nontransient) facial erythema of rosacea i.e. not really for the redness of a flush that would normally subsdide.
  • Mirvaso will be available in the US in September 2013
  • Mirvaso is only for adults over 18 years of age.
  • Mirvaso is to be applied once per day
  • A pea sized amount of Mirvaso should be applied to the forehead, chin, nose and each cheek. Expect a tube of Mirvaso to only last a few weeks !
  • A tube of Mirvaso will be available in 30 grams and 45 grams.
  • This is the first official FDA approved treatment for the erythema associated with rosacea
  • Treatment with Mirvaso has been shown to be safe for up to 12 months
  • The most common adverse reactions are ; redness ! yes extra redness !!, flushing, burning and contact dermatitis. So you don’t want to be one that gets a bad reaction from Mirvaso as you will be worse off that when you started Sad smile
  • It may take 3 to 4 hours for you to see any adverse reaction to Mirvaso.
  • It is not known whether Mirvaso is safe for pregnant or breast feeding mothers.
  • Other side effects include rosacea – huh?, nasopharyngitis (cold like symptoms), headache and increased pressure inside the eye
  • Further, Mirvaso should be used with caution with in patients with depression, cerebral or coronary insufficiency, Raynaud’s phenomenon, orthostatic hypotension, thromboangiitis obliterans, scleroderma, or Sjögren’s syndrome. Alpha-2 adrenergic agents can lower blood pressure so be aware if you have cardiovascular disease.
  • Mirvaso will cause severe reactions if you ingest it. Keep Mirvaso gel out of reach of children
  • Mirvaso is not to be eaten, not for your eyes and is not for intravaginal use.
  • Mirvaso is pronounced Mer-VAY-soe – just so you know ! Sounds like they want you to think of O-RAY-sha (Oracea) when you say it.

Your Question

Do you have a question about Mirvaso ?

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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97 Reader Comments

  1. Bill White says:

    How much will it cost?.Why doesn’t my dermatologist know about this yet? Should I ask my pharmacist?

    • Alan says:

      CVS in south Alabama 295.20
      Independent Pharmacy probably in the 260 to 265 range
      Available currently at Smith Drug ( a supplier for independent pharmacies )
      Mine did not. Not as impressed as I hoped to be, but only on my 4th day.

    • Layla says:

      DON’T do it. Please learn from everyone else’s mistakes….this drug will make your redness three times worse than it was before you started using it. it works when it’s on, but unless you’re completely dependent on it, your face will be hot, flushed and horrific looking once it wears off. It seriously seems to only be working for 1/10 people I see on forums. Do NOT do it, we’re all worried we have permanent damage.

      • A says:

        Exactly. I already have been back to my derm asking if its possible it could have damaged my skin…he said no…that’s its just inflammation…but Im having a hard time believing him.

        • liz says:

          I too am having bad rebound flushing….far worse than my standard red.
          Can anyone tell me if this gets better with time? It has been two days since I last used it. Can I expect my skin to return to normal sometime soon.
          So frustrated!!

      • rebecca says:

        Did your flushing ever stop after mirvaso? I’m on day two of being off of it after 3 days of use. I flush for 6 hours at a time

        • Holly says:

          Rebecca, my flushing has gotten better but I still have redness that is worse than before but I’m hoping over time that will go away. However I did have an episode two days ago that was bad but I hadn’t ‘t had one for a couple of weeks. I hope it continues to fade away.

          • rebecca says:

            How long have u been off it? Were you a flusher before?

            This is so awful. Thnx Holly

          • Holly says:

            I have a general redness with episodes of flushing but hadn’t had those episodes for several months until I used the mirvaso. I think by about a week after stopping mirvaso, the flushing eased.

          • Linda laun says:

            Holly, how is your redness now?

      • So everyone that was worried about having permanent damage!! Did you guys have permanent damage?? I ended up in the ER with the rebound flush side effect. Im very sad that it might not go away 🙁

  2. It was only approved this week and will be available starting next month so it won’t appear on any prescription lists for a while yet.

    No indications of cost yet. Expect Galderma to charge as much as they can as they have a significant R&D effort to get a return on.

    It will be interesting to see what prices people discover in the coming months.

    Like many prescriptions, for those without full insurance, I fear Mirvaso may prove to be unobtainably expensive.

  3. George says:

    I am a little confused about this. They are stating that rebound redness is a common side effect of this drug and we already know that people experimenting with this active ingrediant also experienced rebound redness. It is basically stating what we all already suspected. If lots of people do experience additional redness I’m going to be very confused as to how it received FDA approval.

  4. Amongst those who used Mirvaso for a month, just 4% experienced redness, and 3% flushing.

    Amongst the 365 days trialists, 8% experienced redness and 5% had `rosacea’ as an adverse event and 5% cold like symptoms.

    So overall your likelihood of an adverse event is low.

    • Layla says:

      What does rosacea as an adverse event mean???

      • Somewhat ironically it means that Mirvaso may bring on rosacea when you didn’t have it before starting to use it. Remembering that Mirvaso is officially for a permanently red face, it is not a 100% given that you have to have been diagnosed with rosacea before being prescribed it.

    • Jill Rivers says:

      I’ve been using it for about a week now and have noticed increased redness. At first I thought I must be imagining it but I can now confirm I am in 5% that have bad results. So I’m out $50! Very disappointed since their publicity photos look so good . Jill

    • Heather says:

      Oh it is MUCH higher than 5%. I’d say 5% DON’T experience more redness.

  5. Gar says:

    I have UHC coverage , but they most likely will not cover this. Is there any cost amounts available yet. Not sure if I can afford this miracle. Thanks…

  6. Lori says:

    My dermatologist just mentioned this product to me today. She initially said I would be a good candidate but after reading the precautions, I don’t believe I will be. I have Sjogrens and want to know why there are cautions for Sjogrens and other auto immune diseases (Sjogrens in particular)?

  7. The Mad Klingon says:

    Like many here I’ve been following the progress of COL-118/Sansrosa for a while now. My Rosacea is pretty sever but the last three years laser treatments have made it manageable. Prior to the laser treatments I expected to be completely incapacitated within 3 years. My hope now is combined with the PDL, Mirvaso will allow me to achieve an almost “normal” level of comfort throughout the day.

    What information is there regarding the effectiveness past 12 months?

  8. No information has been made available about use beyond a year. I imagine that multiple year usage will be similar to one year as 12 months is a long time to use a prescription and all side effects ought to have surfaced by then. The expense of a trial as long as year will probably mean that longer ones might not eventuate. In a couple of years time there could be Phase IV trial results from a large population over many months, so I think we will have to wait until then to see for sure.

  9. liz says:

    I got the brimonidine eyedrop from my Dr. For 13$…u can always make your own if its too much $

  10. Jill says:

    Will Mirvaso be helpful to reduce facial blushing?

  11. Steve says:

    when will this reach australia?

    • Hi Steve, there is no information available on when/if it will be released in Australia.

      So if one wants to speculate ….

      It is entirely up to Galderma to decide how to tackle the Australian market. They can decide to try to get it listed on the PBS or make it available unsubsidised. A lot will depend on how well they can show that it is novel and worth the Australian Government subsidising it. Perhaps there is an argument that because it is the only approved topical treatment for rosacea redness it should be listed on the PBS. That path would take in the years timeframe.

      For eg. see that Oracea and Metrogel 1% are not available in Australia, I suspect mostly because they are not significantly better than the already available alternatives so would never get on to the PBS.

      That all assumes it is a priority for Galderma. The European market is so much bigger and they do seem to be more advanced in their approval process for Europe so my guess is that Australia will be well behind Europe for the availability of Mirvaso.

  12. edward says:

    Will it help seb derm redness?

  13. Peter says:

    FYI
    ordered at my local CVS and the copay with insurance is $160
    and there is a cost reduction card which helps a little

  14. Deb Foreman says:

    My derm gave me a sample. Didn’t work on the redness. The script will cost $60 with insurance at Walmart. I won’t be paying for it.

  15. Lois says:

    My husband just received a prescription for Mirvaso 30g. The co pay with our insurance is $40. The reciept states that the retail price without insurance is 274.54 (Meijer pharmacy). OUCH! He has not started using it so I can’t comment on the results.

  16. Nikki says:

    I have been using Mirvaso for 3 weeks now. I am experiencing horrible facial flushing with itching and burning on my skin and eyes. My symptoms are far worse after using this product. The rebound flushing is so bad that people are constantly asking if I am feeling ok. I want to crawl in a hole and hide until this subsides. Very bummed about this. I work for a Dermatologist and my guess is that he won’t be prescribing Mirvaso much. Maybe I am a small % that have such a severe reaction, but I would ask for a sample before I forked out any money for this product.

  17. Matt says:

    I’ve been using this for about 2 weeks and I have to say I’m bowled over! 10-20min after application, I notice a really big reduction in redness and it lasts all day. (The 12 hours they claim sounds about right.) Metrogel never did more than prevent some big flareups and kept me at a lower baseline redness- this stuff removes the red almost entirely.
    Just wanted to post a good story after reading that unfortunately some people are having adverse reactions.

  18. Mary says:

    I just started using Mirvoso last week. So far it is taking the red away. I can tell when it wears off though late at night, my face gets warm. But it doesn’t look terribly red when that happens.

  19. Susan says:

    The first day I used Mirvaso it worked pretty well. By day 5, my skin was extremely red. i have been using it sporadically since then. i have tried (as suggested) applying benadryl cream first. not sure this is effective. and i have developed some papules after. there isn’t much information about applying other products on top of it, i.e., moisturizers, sunscreens, foundation primer, foundation, etc. i finally did see something about applying foundation after it dries.

  20. A says:

    I too am in the rebound group: it works wonderfully for the 12 hours it’s suppose to–however when it wears off…the rebound redness/flushing is unreal…it looks like nothing I have ever seen before…and it hurts. My skin has always been a little flushed…but nothing like this. We’re talking fire engine, burning red. I wish I could post a picture. It might look great for awhile with this cream– but the rebound effect just isnt worth it. Id rather have real skin….PS, with the discount card my derm gave me–it cost $50

  21. Shelly says:

    I just tried Mirvaso as a sample from my dem and boy do I regret it! Yesterday was the first day I used it and I will admit I was initially impressed with it. It took away the red splotchy marks on my cheeks and forehead. I never saw my skin look that clear in years. The beautiful clear even tone skin lasted all day and then night time came. I took a shower, did my usual minimal skincare routine and then as the night progressed I began to feel my cheeks itching and getting hot. I looked in the mirror and the areas that I applied Mirvaso were very red. I have not seen redness like that since I had my horrific outbreak about 6 months ago. I began thinking if I ate anything on my do not consume list because it triggers outbreaks but I didn’t. The only thing I could think of that changed was applying Mirvaso. I went to bed frustrated and hoped wth rest it would get better. I woke up this morning and the redness did subside but I did notice some acne like spots had developed on the areas that felt the hotest and itchiest the night before. I applied Mirvaso one more time to see if it was the cause I can say for sure without a doubt it is. I can see redness peaking out from my foundation and my skin normally does not do that. My cheeks are itchy and those spots are becoming more prevalent. Thank God I did not buy this horrible product. Serves me right for trying another prescription product. I will just stick my natural treatments because for me that has helped me the most and improved my skin.

    • Jill Rivers says:

      I had similar experience, as in VERY BAD. I think they should take this stuff off the market !

      • Mary says:

        Used mirvaso for mild redness especially around my nose. It worked so good so…I used it on my cheeks AND nose! After 3 days I noticed TERRIBLE rebound redness! Never ,never, never, EVER had redness and heat like I am experiencing! Stopped using Mirvaso and hoping this rebound redness goes away. I want my old face back!

  22. Holly says:

    I wish I had researched this more before trying. Day one all redness wa gone. So much so that I looked pale’. Day two same thing except later that afternoon I experienced severe flushing. Did not use today but around noon flushing came on and it is now 8 pm and my face is still hot and red. Praying it is not permanent.

  23. Linda Laun says:

    I have been using Mirvaso for about 3 weeks now. I look like I have Lupus when the medicine wears off, which lasts only about 8-10 hours for me. My dermo gave me samples initially and today I went to fill the prescription ($285 at Walmart) which had to be ordered. Not in stock usually not a blessing but today I thank my lucky stars because I will not be picking up this prescription. I had hope the flushing would diminish with time while using Mirvaso, now I hope it will diminish after I stop using. I did not do my due diligence and will be telling my dermatologist what a horror story this medicine is.

  24. Sarah says:

    ABSOLUTELY MORE than 5% with rebound redness… And I’m yet another one.

    I work at a dermatologist’s office & have heard nothing but that particular complaint from our patients. I used it myself, and experienced the undeniable same: fabulous results when using it & horrific worsening of redness (I look painfully sunburned!!) the second it wears off. SO disappointed…

    • rebecca says:

      This might sound crazy but can we sue them for this cream? I now have such bad redness on my left cheek and flushing. I’m so pissed.

  25. Stephanie says:

    I wasn’t expierincing any flushing until I tired mirvaso. This gel made rosacea far worse, I have never seen my skin this red ! Ever since I used it I been fushing like literally everyday, parts of my face that wasn’t red are now red and my face gets so hot and very red and swollen not even makeup can cover it up. Please be aware of this gel

  26. NN says:

    Folks, PLEASE, do a patch test BEFORE using this all over your face. patch test for several days in a row just to be sure.
    So far I am not having any redness or rebound redness but I did do a patch test before using on my entire face. After the patch test on my arm, I applied only to my chin for two days, now my entire face.
    I’m so sorry folks are having problems. Rosacea already sucks, then to have it worsened by a drug that’s supposed to help, really sucks.

  27. rebecca says:

    I’m 7weeks post mirvaso and my skin hasn’t totally calmed down. I still get flushing some nights and now can’t even touch alcohol. Does it get better?

  28. d_girl says:

    I’ve been using it for a few days a week for several months. I get an application flush (as I do with everything, but a little more so) that fades in 10-15 min. Then no flush for at least 4-6 hrs.
    My derm said to use half a pea size, so it’s lasted a while.
    I never wear base or moisterizer and only rinse my face. Maybe some of you are getting a reaction with your makeup or a cream?
    My rosacea is mild to med, heavy flush and warm feeling, rare pustules.

    • Leslie says:

      wow, good for you! I think you are one of the rare cases where it actually works for you! I put it on alone, no lotion or makeup.

    • Janice says:

      I’m experiencing the same as you & am also at the same level of rosacea problems. I started using the gel on March 12 & plan to continue using 1/2 pea size amount for a while longer. I have noticed more redness after Mirvaso wears off in approximately 8 hrs- which is sad because that’s when I’m usually out to dinner or doing other things with family & friends. Redness from any type physical activity has been magnified. Perhaps my thinking that the rosacea is getting worse should be directed towards the use of Mirvaso. I’m sad for all of us. If someone could actually find help for us, they could make a gazillion dollars. FYI I’ve tried acupuncture for digestive problems & at times that has helped- does anyone else experience that problem? It may be a cause of rosacea. ??

  29. kitchrn says:

    I received a sample of this from a dermatologist. My rosacea has been relatively mild, but I did experience rebound redness and bumps after 2 applications of Mirvaso. This is my experience: I received instructions to apply the product liberally all over my face (not just on affected areas as this could cause a patchy appearance) and wait 30 minutes before applying makeup. Within 45 minutes the redness had definitely disappeared, leaving me with a rather startling gray pallor. After I put on makeup it looked good, but if I were going without makeup I would prefer to stay with the red as it at least appears that I am in the land of the living! The effects lasted about 9 hours. Later, the redness and bumps appeared more pronounced than before. I thought that perhaps it was my imagination now that I had seen my skin without any color, and the redness just seemed more noticeable in comparison. After the second application wore off, it was even more noticeable, and my husband noticed that my face was much redder than usual.

    The most concerning possible side effect for me, however, was lowered blood pressure. My blood pressure always runs on the low side, around 100/70, and if I’m dehydrated it can dip down to the point of feeling faint. After applying Mirvaso I experienced the symptoms of feeling lightheaded. Later in the day I checked my BP and it was 80/60. That’s when I looked up Mirvaso and found that it is an Alpha-2 Adrenergic agonist, which can lower blood pressure. It’s easy to forget that topical creams are still medications, and absorbed into the bloodstream. I would never take an oral med without doing a little research, but give me a face cream and I’ll slap it on without question? I should know better. Always read the product insert before using!

  30. Tammy says:

    I just got this medication yesterday, I tested it on a small area and it turned pale, such was what my dermatologist told me would happen. So, I proceeded to lightly page it on my face as I was directed. The only reactions I’ve are mild headache and a little pressure in my eyes. My face felt a little hot but today it’s not too bad. I’m also on Finacea at night. That stuff made me feel itchy but bearable. Getting my husband to understand that this is a generic thing has been hard, he doesn’t understand that this is new to me too. My insurance covered this somewhat, I paid $55 @ CVS here in California, and I got $5 off with the prescription card I got from my derm. The regular retail here is $126 according to the breakdown on the receipt.

  31. Leslie Howard says:

    I used Mirvaso 3 days and it seemed to work, fourth day I had severe pain and redness, worse then drinking alcohol or exercise. I am on the 3rd day of nonuse and still have the redness and flushing, starts midday and lasts several hours. I have reported to FDA and to Galderma. This is the worst results you could ever get from a rosecea medicine. Pain and embarrassment is NOT what I needed more of. I paid $50 using a card Derm gave me. I asked Galderma for a refund.

    • Leslie says:

      Update…I rec’d an email/letter from Galderma w/a request to call them. I talked to a nurse, she asked more details of my use of Mirvaso, etc. She was nice and professional, obviously not the first person to have this issue. She is going to send a letter to my home for me to complete as well. Day 4 of me not using Mirvaso, hopefully I wont have the horrible pain and flushing today.

  32. Laurie says:

    Mirvaso has made my face look worse than ever before. 🙁

  33. Laurie says:

    Let me know if you get a refund…. I want one as well.

    • Leslie says:

      I will let you all know…I filled out all the paperwork and mailed it in. The nurse on the phone said she would reimburse me. My face isn’t 100% back to the way it was before, but much better. Seemed like it took at least a week for the red/painful spells to stop.

      • Jennifer Pearce says:

        Leslie, is your face better now? I only used it one time, and I hope my face gets better. i have red bumps where I applied it, and redness.

        • Leslie says:

          No refund from Galderma yet, but at least my face is more back to normal. I seem to be getting more red bumps and breakouts than I used to. But hard to contribute that to Mirvaso. Good luck to everyone.

  34. Jennifer says:

    I am like so many of you, I went to see a Dermatologist, she gave me a sample of Mirvaso, with the only instruction of “just use a little bit, it lasts for 12 hours”. No instructions about letting it dry and don’t apply any makeup. The first day my skin looked good, no redness. While at work the first day, I felt faint, but I didn’t connect that to the Mirvaso. I had a lot of the physical symptoms others have described here. I am thankful that I only used it one day and one side of my face looks better, but the other side is broken out, hot, and red. Hopefully by Monday, it will look and feel better. I can relate to the post where she said we read the side effects of medicines we are prescibed, but not for a cream. Big mistake on my part. I won’t go back to the Dermatologist I saw. I did call back and let her know of my symptoms, she recommended putting a hydracortisone cream. I’m not putting anything else on my face until I have to on Monday for work. I’m also turning 51 soon, I want to look and feel great, not onlder and yucky! FOR ANYONE CONSIDERING “TRYING” MIRVASO, DON’T DO IT!!!

  35. Lorraine says:

    I’m so glad I found this site! I’ve been using Mirvaso and after a week became suspicious I was having a rebound effect because my red face is worse then ever! After just finishing 3 months of IVIG treatment at the hospital for dermatomyositis and the red should be gone!

  36. Leslie says:

    I wish there was a way to post pictures…has anyone tried, or asked already? Thanks!

  37. Janice says:

    What’s the latest?? Anybody?? I realized that my rosacea, instead of getting worse on its own, is due to Mirvaso. I started May 12, stopped today! Made me very pale, blood pressure was low, and then a lot redder after about 6-8 hours & extremely hot & swollen. Will not use it again- formula needs to be adjusted.

  38. Ivy Ellis says:

    Sad, Angry, Hopeful.

    • Rebecca Galavan says:

      I’ve been off Mirvaso for 7 months. Before mirvaso my skin never flushed. Now it does so randomly but one time every day. I’m doing everything you could possibly do to help rosacea and my skin still flushes nightly. Starting to wonder if it’s a reaction still to mirvaso. Cause mirvaso made me flush at night really bad. Has anyone else had this happen this long after using it for only 3 days ?????

  39. Christine says:

    Do NOT take this if you have Raynaud’s or Sjogren’s!!

    My dermatologist gave me samples of this (and the danger of samples is that you don’t get the warning information.) One day I noticed that my lips had turned completely white! It only happened once, and like an idiot I didn’t tell the doctor. I didn’t really know if it was from the medicine, or from my other medical issues so I didn’t think about it too much. And for some reason I wasn’t think about topical creams as strong medicine that I needed to be careful with. On my next visit the dermatologist gave me a prescription. My insurance luckily paid some, but I still paid over $170 for 2 tubes.

    The first thing I see on the pharmacy warnings is to not use this medicine if you have Raynaud’s phenomenon and Sjogren’s Syndrome. I HAVE BOTH!! No wonder my lips turned white! (It never helped the redness by the way!) Why did my doctor prescribe this for me??!! She had a list of EVERY medical issue I have & EVERY medication I take. Wasted $170 and used a medicine that could have actually harmed me!!

    Doctors don’t read, don’t listen, they push the latest drug without understanding the ramifications. Do your own research on the medicines you take…even the topical creams!

  40. RS says:

    I started using Mirvaso this week and I think it was a big mistake. Normally, I have occasional mild redness but I flush whenever I have anxiety (public speaking for work fairly regularly), if i am embarrassed, if I drink too much, or if I’m in a warm room. I also have sebborrhic dermatitis that is pretty mild usually on my face on either side of my nose.

    I have found that a healthy lifestyle, working out (although I get red from that too temporarily), and lots of water is very good at keeping the symptoms down. I also have been getting IPL laser treatments periodically which seem to help reduce redness.

    On Monday, I saw my dermatologist for a laser treatment and he also suggested I try a new product, Mirvaso. I used it on Tuesday-Friday this week. At first, like many others, I was amazed. On the first day, my skin was the lightest and clearest I had ever seen it after about 30-60 mins after application. I was ecstatic. However, that day, I had to give a presentation at work, something that always gives me anxiety and causes me to flush, although I’ve learned how to minimize that generally. However, this time, with Mirvaso on, it made my cheeks super bright fire engine red. I didn’t realize until afterwards when I stopped in the bathroom. I was horrified.

    The next day when I woke up, I was somewhat red but not too bad. I used Mirvaso again and it worked again at first but then throughout the day I kept noticing weird patterns of flushing in random places on my face– and I applied the gel evenly across my face.

    Fast forward to Friday. I had been getting more of these strange flushing patterns across my face. My cheeks would get very red and then subside and then start up again. On Friday night, I went out with some friends and had one beer. I went to the bathroom and had these two huge red stripes forming down the sides of face, not my cheeks. When I came back to the table people asked if I had a sunburn on my face. Later that night, within 1-2 hours later when I got home, my entire face was the reddest I had even seen it. My cheeks and my nose were the worst–and my nose NEVER gets red. It looked horrible and became super hot and tingling and uncomfortable. I finally took an ice cold shower and that helped to bring the redness down somewhat.

    This morning when I woke up, my cheeks were flushed again, far more than normal but not as bias as last night. I am afraid to use any more Mirvaso. I definitely won’t try it again. My face was doing ok last week and now it’s worse. After reading this board I am really hoping that the damage is only temporary and will wear down by the time work rolls around on Monday.

    If anyone has any advice or suggestions please let me know. I feel very depressed and embarrased about my face and want to basically hole up at home for the weekend.

    Thanks.

    • Leslie says:

      RS…so sorry tthat happened to you. I had the exact same reaction. I had the severe redness in places I didnt even apply the cream. It does eventually go away…and I mean after you stop using it.

      • RS says:

        Thanks Leslie. I really hope so. After a full day of no Mirvaso, my skin has been all over the board– from red to almost normal back to red, but in very splotchy, unusual patterns. I think using Mirvaso has basically made my triggers super exaggerated now. I guess all I can do is wait it out and hope for the best at this point.

        Is your skin back to normal pre-Mirvaso conditions now? How long did it take for you?

        • Leslie says:

          I used it for 3 days and it took about a week to return to normal. I used a hydrocortisone cream and it seemed to calm it down a bit. Yes, it was very painful and scary. Galderma did give me my money back at least..

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