Mirvaso – Frequently Asked Questions

mirvaso-gel

Surprise news today that Mirvaso, the product formerly known as Sansrosa, CD07805/47 and Col-118 has been granted approval by the FDA.

Here are some of the things we already know about Mirvaso ;

  • The prescription gel will be 0.33% brimonidine (this means each gram of the gel contains 5mg of birmonidine tartrate, which is the equivalent of 3.3mg of brimonidine)
  • The tagline for Mirvaso is that it “works quickly and lasts up to 12 hours”
  • Mirvaso is officially only for the persistent (nontransient) facial erythema of rosacea i.e. not really for the redness of a flush that would normally subsdide.
  • Mirvaso will be available in the US in September 2013
  • Mirvaso is only for adults over 18 years of age.
  • Mirvaso is to be applied once per day
  • A pea sized amount of Mirvaso should be applied to the forehead, chin, nose and each cheek. Expect a tube of Mirvaso to only last a few weeks !
  • A tube of Mirvaso will be available in 30 grams and 45 grams.
  • This is the first official FDA approved treatment for the erythema associated with rosacea
  • Treatment with Mirvaso has been shown to be safe for up to 12 months
  • The most common adverse reactions are ; redness ! yes extra redness !!, flushing, burning and contact dermatitis. So you don’t want to be one that gets a bad reaction from Mirvaso as you will be worse off that when you started Sad smile
  • It may take 3 to 4 hours for you to see any adverse reaction to Mirvaso.
  • It is not known whether Mirvaso is safe for pregnant or breast feeding mothers.
  • Other side effects include rosacea – huh?, nasopharyngitis (cold like symptoms), headache and increased pressure inside the eye
  • Further, Mirvaso should be used with caution with in patients with depression, cerebral or coronary insufficiency, Raynaud’s phenomenon, orthostatic hypotension, thromboangiitis obliterans, scleroderma, or Sjögren’s syndrome. Alpha-2 adrenergic agents can lower blood pressure so be aware if you have cardiovascular disease.
  • Mirvaso will cause severe reactions if you ingest it. Keep Mirvaso gel out of reach of children
  • Mirvaso is not to be eaten, not for your eyes and is not for intravaginal use.
  • Mirvaso is pronounced Mer-VAY-soe – just so you know ! Sounds like they want you to think of O-RAY-sha (Oracea) when you say it.

Your Question

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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97 Reader Comments

  1. Sandra says:

    I’m so glad people have been writing comments. I was about ready to ask my doctor to prescribe this stuff for me. Metrogel does absolutely nothing, IPL is great buy I have no insurance coverage for it and it’s expensive, and I need to keep doing it each year. 10% chance of rebound flushing isn’t so bad, but I get the feeling that the actual figure is higher, and I don’t think I want to take the chance. And the more I thought about it, if I pay $50 per month I’ll spend $600 per year, that more than covers IPL treatments. I’ll just stick with IPL.

    • Rebecca Galavan says:

      I used mirvaso for 3 days in Dec. I never had flushing. Now I flush every day and have ocular rosacea. Coincidence ? This has totally messed up my daily life. It awful.

  2. Suzi says:

    I am updating my previous post on this site. After a few days of using the samples provided by my dermatologist I decided to take prescription to pharmacy here at the hospital where I work. Our cost is only $20. But unfortunately my face got redder and redder and dryer and dryer. I also had a very runny nose. My rosacea has never been severe and is now. I called the pharmacy and cancelled the prescription. Very very disappointed. I’ll just stick with laser treatments. It may work for others, but definitely not good for my skin.

    • Jen says:

      Hi! Just wanted to share my Mirvaso experience. I used the samples from my dermatologist for 3 weeks. I must say it worked like a charm for the first week. During week 2 I noticed during the day my skin would flush and feel very hot. A small red patch on my cheeks would form and last for a couple of hours. This redness eventually would spread to cover both cheeks and up near my temples. Eventually the redness would go away but people at work were asking me what was up. Mind you I tried using make up to cover it and still it was visible. By week 3 I noticed my cheeks had a bad rash it turns out is contact dermatitis. It’s red, itchy and has tiny bumps. Now I’m never using Mirvaso and I’m left with more redness and irritation than when I started using the stuff. My experience with Mirvaso is it worked for a short time and then stopped working and made things worse. I hope with time my skin goes back to the way it was. I’m on day 3 now of no Mirvaso just trying to soothe the contact dermatitis. Hope my story helps others. Mirvaso Users Beware!

      • Noreena says:

        Hi! Just started using Mirvaso a few days ago. Could not believe the difference within just 2 hours my face was normal skin color and I was so happy. I was asked to apply Mirvaso at night and the following day when i awoke my face was red. applied dermacool to get the redness to subside. I flush and go red when i get anxious or do anything that takes effort such as hoovering or cleaning the house, even minor tasks blood flow goes directly to my face. I have a few minor blemishes that break out and have been prescribed oxytetracline.
        I had been using just plain cold cucumber on my face before using Mirvaso and that actually took the heat out of my face and calmed it down. Now reading these comments on Mirvaso from other patients I am reluctant to continue this treatment.

        • Noreena says:

          Hi again. Just want to update my previous post of the 13th July 2014. I have commenced Mirvaso again thinking that maybe I would be lucky and have a good response to this gel. However, my face can be like the rising sun and boiling hot to the touch. Could prob cook an egg on it. This is a very realistic view as my whole face would be red. Also, I have experienced this blotchy part of skin going red. When i awoke one morning my face was really not to bad, then my forehead broke out red, put dermacool on it and red went away and re appeared on my cheek, applied dermacool, red patch went away. then more patches appeared even on areas that i did not every apply Mirvaso to, such as my jaw line and side of neck. By the evening time my whole face was blazing hot. Went to see Gp who said I was “beaming”, great that really helped! Just said that i was flushing and that was expected with rosacea. I have been increased now from one anti histamine now to two. Chlonidine commenced about 5 days ago and was told to up the dose. Now taking 50mg and anti histamine at bed time, and sleep like a log. Makes you feel a bit dopey in the morning time. I hope i can get this under control as it really does make my life miserable. I just dont understand how I can have a red patch and then it goes away and comes back somewhere else. Does anyone else experience this – is this a normal rosacea pattern? I would generally say this redness is getting much worse and the flushing def is. D0ES ANYONE ELSE EXPERIENCE THIS WEIRD BLOTCHY SKIN WHICH APPEAR GRADUALLY ON FACE, THEN FADE AND COME BACK AND THEN FACE IS BLAZING HOT ALL OVER INCLUDING NECK AREA?

      • Sue says:

        Hello Jen, I had the same experience it was magic at first site for a week or two and at times it would wear out n small patches of redness started appearing on my face making it look worse then what I first thought was bad! Then week three my face started flushing very bad im talking about my face looked as if I got sun burn then my face was getting dry about that same week I noticed a rash on the side of my face with little red bumps that I never had it was irritating so bad and looked awful I stop using the mirvaso! Never again would I use it! I don’t recommend it to anyone!!!

  3. liz says:

    Hello Everyone,

    I also had bad rebound flushing with Mirvaso.
    I wrote to Galderma and filed a complaint online to the FDA.

    I would recommend everyone else to do the same so they can take Mirvaso off the market and hopefully start the R&D process to develop a version that does not cause rebound redness.

    I do not understand why it is still being prescribed given I have seen hardly any positive reviews.

    Thank you

  4. Andrea says:

    I have only been on a sample for 4 days and I won’t be getting the prescription filled. My redness is worse. I’ve never had bumps and now I do and I’ve had a headache since I started on it. At least I didn’t pay for it.

  5. Sonya R. says:

    I a few samples of Mirvaso at my yearly checkup with my dermatologist. I applied it to my checks and chin last night and today my checks and chin are so red I would be embarrased to go in public. Looks I literally burned my face with a horrible chemical. My eyes are burning. I will call my dermatologits tomorrow and tell her I am not filling the prescription and I will stick to Finacea cream. I’m hoping the redness subsides before I have to show up for work in the morning. Very disappointed in this new treatment.

  6. RS says:

    I just wanted to update my previous post. I tried Mirvaso for three days a couple of months ago, and like many others had an absolutely horrible experience. I turned redder than ever, even in places where I had never had any trouble before, and would experience random bouts of flashing throughout the day (to make it even more awkward, it was very splotchy and sometimes just one cheek would turn completely red). Needless to say, I was embarrassed to leave the house.

    Nearly two months later, I am back to normal–or at least where I was pre-Mirvaso. I went to see my doctor about a week after I stopped taking Mirvaso. He gave me a temporary soothing balm–I cannot remember the name right now, but it was a heavy duty steroid cream of some kind that he said I could only use for a few days. That helped get me under control quite a bit. The weird flushing stopped. He also put me on Oracea (Doxycycline), which seems to be working pretty well in combination with Pulsed Dye Laser (PDL) treatments. I also use Ketocozonale for some sebborhic dermatits on my face.

    The point of my post is– there is definitely hope for getting back to your normal, or pre-Mirvaso state. It takes time…and I felt like it took forever, but eventually, it runs its course. So don’t give up hope. If you have a good dermatologist, he/she should be able to help you get back on track. I would suggest going to see your doctor immediately if you’ve just taken Mirvaso and are starting to experience the side effects. I will never in a million years touch this stuff again.

  7. Danny says:

    Thanks for all of the comments.I see my doctor in December. I, too, have experienced all of the symptoms from using Mirvaso. In fact I look like a clown most of the time as the redness is so bad.I definitely will stop using this product! I would just like to look normal again and have people stop asking me about my face.I have have two light treatments, which work for awhile, but the redness always comes back. Do not use this product!

  8. lynn says:

    My dermatologist has said I should try mirvaso and finacea for my rosacea. After reading these posts dont think I want try mirvaso.

  9. Dianne says:

    Mirvaso worked but my skin was extremely dry after and had redness break through am not near a derm so am trying to find help on line.Dissapoined once again.Rosacea with super sensitive skin hard work.Depression is worse due to lack of nearby derm help GP knows nothing either.

  10. Janice says:

    I tried Mirvaso- horrible redness & heat- was told it may do that in beginning- became severe so I stopped after a few weeks. I’m now using Zenmed natural products for redness & a mineral powder for coverage. Still get much redder than before with activities or being outside – which I love! This product should never have been approved by FDA. So sorry for everyone-please try Zenmed.

  11. Deborah says:

    Oh dear I have just received my 1st tube of Mirvaso. Being caseous I decided to try it on a small area. I was pleased to see how it took the redness away but worried if I did my whole face I would look ghost like! Has anyone tried diluting it with a moisturiser? After reading some of the other comments I daren’t try any more but was really looking for a quick fix.

  12. Cathy says:

    I have been given a script for Mirvaso but now after reading all these comments I don’t think I’ll risk it as I also have extremely sensitive skin. Has anyone tried the Soolantra cream? It has 1% ivermectin and is mainly used for papules and pustules, so more for acne rosacea. It isn’t available yet in Australia but my derm has filled out a script so I can get it made up at a compound chemist. The reports from the trials seem good. I wonder if it helps with redness as well…

  13. Cathy says:

    The same ingredient in Mirvaso is in eye drops that are used to clear the redness from your eyes. I recall the chemist telling me only to use the eye drops for 3 days because after that I’d get a rebound effect and the eyes would get much redder than before. Perhaps the same caution should be applied with Mirvaso – 3 days use, then stop using for a week or 2, (or even longer??) then try again. Be interested to see if this method works for anyone…

  14. Chan says:

    I have rosacea and adult acne problems over decade, used many products but nothing worked, finally my doctor gave me couple of Mirvaso samples to try, I used it for almost a month now, it seems to work. By the way, my doctor recommended to use Cetaphil cleanser first, then followed with Mirvaso in the morning, Epiduo at night for adult Acne. After the cleansing, I always use 100% pure Moroccan Rose Water as toner to control the redness. Couple days ago, I ran out of samples and asked for the prescription, I couldn’t believe what I heard, it will cost me $650 for both! Even it works, I cannot afford it.

  15. Gem says:

    I applied Mirvaso for the first time tonight. Then I came to this site and found most of the comments to be negative. After having Mirvaso on my face for about ten minutes, I washed it off and will not be using this product. I hope it didn’t have enough time to do any damage. I have a mild form of Roseacea and I sure do NOT want to exacerbate my situation!

  16. Cecilia says:

    Can it turn your lips pale?

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