Long Pulse Dye Laser and Nd:YAG (Cynergy Multiplex) used together

Written by on September 13, 2007 in laser therapy, pulse dye laser with 3 Comments

This just published paper is a case report of one 60 year-old patient who was unresponsive to the usual first line rosacea treatments. Additionally 2 treatments with Lumens One IPL were unable to offer clearance. The patient then received 2 treatments with the Cynergy LPDL:Nd:YAG Laser.

Recalcitrant rosacea successfully treated with multiplexed pulsed dye laser.

J Drugs Dermatol. 2007 Aug;6(8):843-5, Larson AA, Goldman MP

There are few treatments that address both papulopustular and telangiectatic components of rosacea. We present a case of rosacea that was unresponsive to treatment with antibiotics. We report the novel use of a new laser technology, the multiplexed laser, for treatment of both papular and telangiectatic rosacea.

The author has kindly sent a copy of the paper, so if you would like to read a copy, let me know. Here is a quote describing the laser used in the report.

Cynergy MultiPlex (Cynosure, Westford, MA) is a new technology combining a long-pulse PDL with a 1064-nm Nd:YAG laser. The 595-nm wavelength targets the yellow absorption peak of oxyhemoglobin. It is thought that the laser also stimulates the ferrous iron (Fe2+) molecule of heme to ferric iron (Fe3+), converting hemoglobin to methemoglobin. Methemoglobin is unable to bind oxygen, and is a greenish-black pigment. The Nd:YAG laser treats this new chromophore more effectively than hemoglobin. Sequential lasering with this combination is thought to be more effective than either laser alone in the treatment of vascular lesions. It not only treats a broader spectrum of vascular lesions at various depths, but also decreases the number of treatments needed.

Disclosure: Dr. Goldman serves as a consultant for Lumenis, Cynosure,
and Dusa Pharmaceuticals but has received no specific funding
for performing treatment or writing this article.

The patient showed a 50% improvement of papules and telangiectasia after one treatment with Cynergy PL. The paper ends by saying that one of the advantages of this combination laser is less need to treat at purpuragenic causing energy levels – i.e. it can offer less downtime compared to other Pulse Dye Laser treatments.

For more information on the laser, see Cynergy Vascular Workstation.

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Read more about: laser therapy, pulse dye laser

About the Author

About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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3 Reader Comments

  1. Mariannw says:

    I’ve tried this expenisve treatment and for a while it helpt, but its very painfull en after 2 years I must say I’m back to

    I wouldn’t recommend it.

  2. Laser Treatments MD says:

    We’ve also had very good results with this.

  3. Li says:

    I have visible veins around both side of the jaw line and prominent broken capillaries evenly across my face. I want laser to even out my complexion and rid the veins. My test spot was done 9 days ago. Hours after treatment, the spot became more red, and I looked like a piece of raw red meat the first 2 days, the redness did subside after the 4th day or so and now it looks brownish. I’m still waiting for the brown spot to totally go away, I hope its not hyper pigmentation. So my appointment to do the whole face is coming up and I’m skeptical. Has anyone done this treatment before? And were the results ideal?

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