A poster session at the just completed 2015 AAD Meeting in San Francisco has published some results that show a special formulation of Kanuka Honey is able to benefit rosacea sufferers.
The information around this announcement tells us that a `large clinical trial has proved that Honevo, a medical grade kanuka honey formulation, developed by New Zealand company HoneyLab, is an effective and safe treatment rosacea.’
The clinical trial results demonstration that 65% of triallists showed an improvement in their rosacea – 34% had a large improvement and in “13% the disease disappeared completely”. Improvements were seen in within 2 weeks.
This is encouraging news for those rosacea sufferers looking for natural treatments.
Honevo – Kanuka Honey and Rosacea AAD Presentation
The author of the paper kindly provided a copy of the 2015 AAD poster session summary.
- A topical kanuka honey formulation is an effective treatment for rosacea (PDF), AAD Poster Session, 2015.
The trial of 137 subjects were randomised to Honevo and to a control. Note that the trial could not be blinded as the appearance and smell of honey precludes this sort of comparison. i.e. trial participants would be able to tell if they were using the active preparation or not.
The main result of the trial was that 24 of the 68 in the Honevo group had a 2 grade or better improvement in their IGA-RSS.
What is the IGA-RSS Score ?
The IGA-RSS used is an assessment done by a practitioner, called the Investigator Global Assessment of Rosacea Severity Score. The IGA-RSS uses a 7 point numerical scale from 0 to 6 to describe rosacea symptoms.
|0||Clear||Almost no Rosacea (i.e. no papules and/or pustules); no or residual erythema; mild to moderate degree of telangiectasia may be present|
|1||Minimal||Rare papules and/or pustules; residual to mild erythema; mild to moderate degree of telangiectasia may be present|
|2||Mild||Few papules and/or pustules; mild erythema; mild to moderate degree of telangiectasia may be present|
|3||Mild to Moderate||Distinct number of papules and/or pustules; mild to moderate erythema; mild to moderate degree of telangiectasia may be present|
|4||Moderate||Pronounced number of papules and/or pustules; moderate erythema; mild to moderate degree of telangiectasia may be present|
|5||Moderate to Severe||Many papules and/or pustules, occasionally with large inflamed lesions; moderate erythema; moderate degree of telangiectasia may be present|
|6||Severe||Numerous papules and/or pustules, occasionally with confluent areas of inflamed lesions; moderate to severe erythema; moderate to severe degree of telangiectasia may be present.|
What is a 2 grade improvement in IGA-RSS ?
The AAD poster session helpfully tells us what the statistically significant proof of a 2 grade improvement in the IGA-RSS actually means.
A 2 point reduction in IGA-RSS represents a clinically meaningful improvement, for example a change from ‘severe’ to ‘moderate’, or from ‘moderate’ to ‘mild’ rosacea severity.
This published research follows on from data from a smaller trial of 10 patients that was published in 2010.
Lets revise – from Topical Kanuka Honey as a Rosacea Treatment ;
What is Kanuka Honey?
Perhaps not as well known as Manuka, Kanuka Honey is also from bees who visit primarily one bush – the Kunzea ericoides bush.
Why is Honey Interesting?
Honey has some properties that may make it useful as a topical treatment for some conditions. According to Honey Sciences from the HoneyLab, honey has some potentially useful properties.
- In treating open wounds, honey is useful as it helps prevent scarring by keeping the skin moist
- is a natural “humectant” as it attracts and retains moisture
- contains an enzyme that produces hydrogen peroxide which kills micro-organisms
- Cuts, abrasions and scalds can be covered in honey to prevent bacteria from entering the wound and promote healing
- pH of honey is commonly between 3.2 and 4.5 and this acidic pH level prevents the growth of many bacteria
- most of the water molecules are associated with the sugars and few remain available for microorganisms, so it is a poor environment for their growth and effectively kills them by depriving them of water
- can destroy biologically destructive chemical agents
The publishing of this research has lead to some renewed coverage in the local New Zealand media.
News Release: Wednesday, 1 April 2015
New Zealand Honey Product is Proven to Help Rosacea Sufferers
Large clinical trial shows that a kanuka honey formulation is as good as prescription medicines
There is new hope for the 5-10% of adults who suffer from rosacea in the form of a medical kanuka honey formulation from New Zealand.
A large clinical trial has proved that Honevo, a medical-grade kanuka honey formulation, developed by New Zealand company HoneyLab, is an effective and safe treatment for rosacea. The clinical trial was undertaken by the Medical Research Institute of New Zealand and was partly funded by a grant from Callaghan Innovation.
Dr Holt says that recent developments in the understanding of the cause of rosacea explained why the kanuka honey formulation was so effective.
“It’s now thought that the underlying causes of rosacea are mites and associated bacteria living deep in the skin in the affected area, and the rosacea symptoms are an inflammatory reaction to these. As medical kanuka honey is effective at killing micro-organisms and reducing inflammation this is an excellent explanation as to why kanuka honey works so well.”
Honevo is applied as a mask twice a day and then easily washes off. This patent-pending kanuka honey formulation contains a small amount of another natural product which improves its physical characteristics which makes it less sticky than regular honey. It’s also far more temperature stable and does not get too runny when hot nor too hard when it’s cold.
What is the Honevo Formulation?
We are told that Honevo Rosacea is a patent-pending formulation of kanuka honey and 10% glycerin. The addition of glycerin makes the honey less sticky than regular honey, less runny when hot and less hard when cold.
How can I try Honevo ?
Honevo Rosacea can be ordered at http://honevohoney.com/. Honey Labs will ship Honevo Rosacea worldwide.
Does it work for you?
Please let us know if you try Honevo and how well it works for you.
The combination of being a natural treatment and now being proven to be somewhat effective will hopefully lead to some good results for rosacea sufferers.
Kanuka Honey and Glycerin, known as Honevo was featured in the TEDx Wellington talk -￼Spreading The Cure | Dr. Shaun Holt | TEDxWellington
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