Get ready for MetroFoam

Written by on October 12, 2011 in Galderma, metrofoam, Metrogel 1% with 3 Comments

A recently updated patent application by Galderma shows that they want to reserve the right to create a Metronidazole Foam product.

Galderma has a long history with topical metronidazole products, starting with Metrogel 0.75%, then adding Metrolotion and Metrocream, and when the patent on the 0.7% Metrogel expired, Galderma created Metrogel 1%.

Past research seems to suggest that it matters little whether you use Metrogel, Metrolotion, Metrocream or Noritate. Further it seems to not matter whether you use these products once or twice per day.

As far as foam based rosacea treatments are concerned, we learnt in 2009 that a clinical trial would investigate whether a foam based form of Finacea was safe and effective.

The foam being patented is described as a “stable, metronidazole-based oil-in-water emulsion expandable into a topically applicable foam having a firm, creamy and light consistency” and is claimed to have improved release-penetration capacity.

METRONIDAZOLE-BASED DERMATOLOGICAL FOAM AND EMULSIONS FOR THE PRODUCTION THEREOF

Oil-in-water emulsions expandable into stable foams having diminished inhibitor of skin breathing and useful for the treatment of dermatological conditions/afflictions, e.g., rosacea, advantageously contain:

(a) 72% to 76% of water;
(b) 0.1% to 5% of a gelling agent for the aqueous phase of the emulsion;
(c) 0.75% to 2% of metronidazole;
(d) 5% to 10% of mineral oil;
(e) 0.5% to 10% of a surfactant;
(f) 0.5% to 5% of a fatty acid;
(g) 0% to 4% of a metronidazole absorption promoter (c); and
(h) 0.1% to 5% of a preservative selected from the group consisting of methylparaben, propylparaben, phenoxyethanol and mixtures thereof.

Domain Name

Galderma have owned the domain name metrofoam.com since 2004, which currently just redirects to Galderma.com. This is a reasonable indication that Galderma wants to hold open the option to release a Metrofoam product in the future – or at least stop a competitor using that name.

Can You Get Excited?

Does the thought of being able to get your Metronidazole dose from a foam do anything for you?

Related Articles

Read more about: Galderma, metrofoam, Metrogel 1%

About the Author

About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

Follow Rosacea Support

Subscribe via RSS Feed Connect on Pinterest Connect on Google Plus

3 Reader Comments

  1. jacque says:

    what about people allergic to parabens? They are in all of these types of products! I’m sure many people with rosacea are sensitive to parabens too!

  2. David Pascoe says:

    Hi Jacque,

    Yes it does seem that almost all products that contain water will contain some sort of paraben. Protecting a product from spoiling, especially those that are water based, is obviously a difficult task as we see so many manufacturers using parabens. Even the `state of the art’ built just for rosacea sufferers, reformulated Metrogel 1% contains parabens.

    We can only hope that they use the minimum amount required to protect the gel and thus give those with sensitivity to them a fighting chance.

    Have you been able to show through trial and error that all parabens cause a reaction for you?

    dp.

  3. jacque says:

    Hi David. So far I haven’t found any that don’t cause reaction. It started a few years ago and I thought it was to peppermint. But then I noticed the reaction was happening with more topicals that had no mint type ingredients. So I had allergy testing this year that confirmed it is actually the parabens.

    However it is an interesting thing that it started only on one spot on the side of my neck. I could use products with parabens in other areas but just not that spot. Then it was my whole neck. The area has continued to spread now to my face and chest. So I assume those might be the most sensitive areas that reacted first and now it is spreading to other areas.

    Is that common?

    Thanks!

Leave your comment here

Top

Subscribe to Rosacea News

Enter your email address to receive the latest news about rosacea in your inbox.