Farmaka Rosacea Cream (Dermalex) Improves Redness

Written by on November 13, 2014 in research with 3 Comments

dermalex-rosacea

Further to the gentle market launch of Dermalex Repair Cream is some vendor sponsored research into how well Farmaka Rosacea Cream (FRC) treats the redness and general dryness of rosacea.

So What is Farmaka Rosacea Cream?

Well every time I see a new product described I of course immediately want to know what it is and wonder does it work ?

The description of the Farmaka Rosacea Cream as containing ” trehalose, cholesterol, ceramide, and fatty acids” sure sounds liked Dermalex Rosacea Cream.

Indeed similar wording can easily be found in a 2009 patent titled Cosmetic and dermopharmaceutical compositions for skin barrier restoration and disorders prevention.

Finally it looks like Farmaka is just the investment body for new products like Dermalex.

So it seems clear that Farmaka Rosacea Cream is the development name for Dermalex Rosacea and Couperose Cream.

Does Dermalex Rosacea and Couperose Cream Work?

Some user reviews are starting to surface. The reviews are so far of a mild benefit. We can hope that over time more real world reviews surface.

Article Abstract

Preliminary open-label clinical evaluation of the soothing and reepithelialization properties of a novel topical formulation for rosacea [PDF]

Clinical, Cosmetic and Investigational Dermatology, 24 October 2014

Background: Rosacea is a common, incurable skin barrier disorder characterized by relapses and remissions.

Purpose: To evaluate the efficacy of Farmaka Rosacea Cream (FRC), a novel topical formulation for rosacea.

Methods: This single‑center, open‑label pilot study comprised a single‑dose substudy in 20 healthy subjects and a long‑term, repeat‑dose substudy in 22 subjects with rosacea. The 2‑hour, controlled, single‑dose substudy assessed the soothing and reepithelialization properties of FRC after stripping-induced erythema based on the erythema index, transepidermal water loss, skin hydration, and clinical assessments of erythema. In the long‑term substudy, subjects applied FRC twice daily for 8 weeks. Clinical assessments included vascular and pigmentary homogeneity and erythema and hemoglobin indices. Subjects completed questionnaires to assess FRC efficacy and cosmetic acceptability.

Results: Greater reductions were seen in FRC‑treated areas compared with untreated areas for the erythema index (-16% versus -8%; P,0.001) and mean transepidermal water loss (-35.8% versus -10.1%; P,0.001) 30 minutes after stripping. Significant improvements over untreated areas were maintained 2 hours after stripping. Skin hydration and clinical erythema assessments also indicated that FRC soothed rosacea symptoms and promoted skin reepithelialization. Erythema and hemoglobin indices were significantly reduced from baseline after 4 and 8 weeks of treatment. Clinically assessed parameters were significantly improved following FRC application. Subjects assessed FRC positively.

Conclusion: Improvement of rosacea symptoms was noted with FRC application. The main film‑forming ingredients of FRC (trehalose, cholesterol, ceramide, and fatty acids), combined with other soothing and calming ingredients and ultraviolet filters, could explain its efficacy.

Conclusion: Short-term application of FRC reduced erythema in healthy  subjects following skin stripping, while longer‑term treatment in subjects with rosacea helped to counter the associated signs and symptoms. The fatty acid and sugar content of FRC could explain its efficacy in the treatment of rosacea.

Acknowledgments: This study was funded by Farmaka srl (Milan, Italy). The  authors thank Insight Medical Writing (Kidlington, UK) for assistance in the preparation of this manuscript.

Disclosure: The study was funded by the manufacturer of the rosacea cream. The authors report no other conflicts of interest in this work.

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About the Author

About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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3 Reader Comments

  1. John says:

    Thanks for letting me know about this but I have already tried it and it didn’t help me although it must help some people. I use a natural cream by mama nature (proskins rosacea) and it has been like a miracle for me. But thanks anyway for keeping me in mind and letting me know about this.

  2. Nick Pellegrino says:

    npell59@charter.net john dose that work to help the redness

  3. liz says:

    This is a godsend to me. I was recommended it a month ago and it is by far the best cream I have found so far

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