Eucrisa approved for Eczema

Written by on January 16, 2017 in Allergan, eczema, prescriptions with 3 Comments

Not strictly a treatment for rosacea, but it is interesting to note that this just-approved drug for the treatment of atopic dermatitis is the first new treatment in 10 years.

The way that crisaborole works to inhibit the PDE-4 enzyme active in eczema is not known – sound familiar ? A few proven rosacea treatments are not well understood.

Pfizer have just purchased the company that developed Eucrisa for an incredible $USD 5.2 billion. Analysts initially expected Allergan to purchase Anacor Pharmaceuticals, but Pfizer won out.

Pfizer Receives FDA Approval for EUCRISA (crisaborole), a Novel Non-Steroidal Topical Ointment for Mild to Moderate Atopic Dermatitis (Eczema)

Wednesday, December 14, 2016 – 9:15pm EST

Pfizer Inc. (NYSE:PFE) announced today that the U.S. Food and Drug Administration (FDA) approved EUCRISATM (crisaborole) ointment 2%, a novel non-steroidal topical phosphodieterase-4 (PDE-4) inhibitor for the treatment of mild to moderate atopic dermatitis (AD) in patients two years of age and older.

AD, often called eczema, is a chronic condition impacting nearly 18 million children and adults in the United States. Approximately 90 percent of people living with AD have the mild to moderate form of the condition.

“The approval of EUCRISA is great news for the children and adults suffering from mild to moderate eczema, a community that has not had a new prescription treatment for more than 10 years,” said Albert Bourla, Group President, Pfizer Innovative Health.

EUCRISA is the first and only non-steroidal topical monotherapy that inhibits the PDE-4 enzyme in the skin. Overactive PDE-4 has been shown to contribute to the signs and symptoms of AD. The specific mechanism of action of crisaborole in AD is not well defined.

What is Eucrisa?

EUCRISA is indicated for topical treatment of mild to moderate atopic dermatitis in patients 2 years of age and older.

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Read more about: Allergan, eczema, prescriptions

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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3 Reader Comments

  1. Lisa says:

    Has anyone had success with Eucrisa? Please let use know!

  2. gle nda says:

    Hi, in regards to Eucrisa. I am waiting to receive it via the post from USA. I live in Switzerland and I ordered it and would cost 1800 US dollars for a 60 gram tube. Now, i am ordering it through the UK and am paying 700 Us dollars for the 60 gram tube. As you can see, i am desperate. i have been off of steroids for 15 months and am in topical steroid withdrawal. I have severe eczema,but will try the creme anyways since it is only for mild to moderate. Amazing how corrupt the drug companies are. Wow, steroids are cheap and I know personally how many kickbacks the doctors receive when prescribing them…. such a disgusting world especially with drug companies….

  3. Lauren B says:

    Otezla worked for me with severe eczema. My dermatologist allowed me to try samples and my hands that were disabilating were clear. Unfortunately, Otezla refused to allow me to be prescribed this medication because it was not diagnosed as plague psoriasis. Back to pain, and inability to use my hands. The doctor just started me on this cream today.

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