The case against Accutane / isotretinoin (AKA. Poison)

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The case against Accutane / isotretinoin (AKA. Poison)

Postby Mike T » Tue Apr 13, 2010 3:53 am

YOU MUST READ THIS IF TAKING ACCUTANE. DO THE RESEARCH AND MAKE YOUR OWN OPINION. READ THROUGH THE LINKS. I GUARANTEE YOU WILL NEVER TAKE IT AGAIN.

http://www.topix.com/forum/drug/accutane

This is officially the worst day in my life.

After reading about accutane ( isotretonoin) in wikipidia i just feel like dying.

It has completley ruined my life. I have found out a similar drug to this is used for chemotherapy.

All the pieces fit together now and I know exactly what has happened to me.

I went to the " adverse effects" section and read the part listing effects which continue after you stop the drug... I have 90% of them. All began shortly after taking this drug for about 1 year.

-I am in the process of loosing all my head hair even though my dad and my uncles are 50 and still have there hair
-I have rosacea even though noone in my family does
-I have severe lower back pain and my whole body feels like im 60 years old. This can be attributed to the algais (type of arthritis side effect)
-I have torn ligaments in both shoulders and am having an operation soon to correct.
-I have sebbhoreic dermaitis
-i have dry eyes

All if these issues occured not too long after I was taken of a high dose of accutane for acne.

I had always had my suspisions and this now proves it.

Noone told me of this before I went on the drug. I am actually laughing now because this is the kind of thing that you would never expect to happen to you.

Please stay away from this drug. Even in small doses people have noted side effects. People who weigh less should take less.

If anyone would like to read the section i read go to wikipidia and type in isotretinoin.

There are over 400 pending law suits against the makers of accutane.it's enough to send shivers down my degenerating spine. I don't want money though I want my life back.

I have found another site which lists the side effects of accutane. A list containing possibly every known disease to man. If I had seen this dictionary of side effects there is no way i would have taken the drug. All I was told is that my skin would be dry over the time I took it...

I just keep comming across more and more information i wish i had seen earlier. How could they sell this to people. How could 25 years of administering this drug could they not come clean. This is worse than when doctors prescribed cigarettes to patients. The THIRD LINK describes in detail exactley how and what taking accutane or high doses of Vitamin A can and will do to you. It is horrific stuff and i am now living with the consequences. I dont know what to do..once i am beyond the point of no return i will find the maker of Roache and make him suffer like he has made me and countless others.

http://www.midiona.com/drugs/Accutane.htm
http://www.topix.com/forum/drug/accutan ... 4DL0NVSN6D
http://www.topix.com/forum/drug/accutan ... 1TLI41VBPN

I am now looking for ways to correct what has happened. I have briefly read that supplementation with magnesium and other antibiotics can help with the joint pain and other side effects of this drug. It is my first day of joining the dots and realising what has happened to me so any research and help from anyone will be appreciated to try and get my joints back on track before i injure myself any more. There is heaps of info in the third link but it will take me ages to go through it all.
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby Mike T » Mon Apr 19, 2010 9:25 pm

Below is the link to the most detailed and referenced report you will ever find to date on Accutane and its side effects. I reccomend anyone considering about or already taken Accutane, Vitamin, Retinoids or any other mineral in high doses to read. Even those with rosacea can benifit from reading this article, it pretty much explains how our body ages and how Accutane screws up this natural process. It is cutting edge stuff and is the centre of evidence the lawyers overseas are basing there cases against Roache on. More and more dermatologists are straying from the closedminded, mainstream ways of thinking and beggining to show support to Nathan's (the Author) findings.

You should download it and read it, especially pages 1-15 and 45-60.

https://www.yousendit.com/transfer.php? ... cFZMWEE9PQ

All the best
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby Mike T » Thu Apr 29, 2010 11:57 am

For anyone else in a similar position to me i will be posting about any treatments i find effective to combat the side effects from Accutane.


First i reccomend a full blood test and suppliment accordingly with the help of a doctor, derm, naturopath or the like.

I have been on Glucosamine with Chondroitin and Magnesium suppliments for the past month. I have noticed a marked improvment in joint clicking, pain and loosness.

I have, a few days ago, started taking a Hyaluronic Acid suppliment called "Doctor's Best Hyaluronic Acid". It has had some great reviews and an additional benifit is that this suppliment not only lubricates joints but is noted to improve skin complexion and moisture. It is basically cutting out one step from taking Glugosamine with Chronodite, which is taken to encourage the body to produce its own Hyaluronic Acid. I will report about this product in time. If it works i will need to stop the Glucosamine as not to get too much of the stuff. Also i am hoping my chronic dryness is a result of too little Hyaluronic Acid which when supplimented may cure me from it and may even help my seb derm + Rosacea which i recieved via unconventional means . May be unlikley but it makes me feel positive to think so.

I stress the importance to thoroughly researching the risks/benifits of taking ANY suppliment and dose. Suppliments can be dangerous. I took Accutane which is essentially a toxic amount of Vitamin A (100x daily limit in one pill), which put me in this mess. Research before is better than research after, like in my case.

Mike T
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby Mike T » Sun May 30, 2010 1:53 am

Just an update.

It seems my joint pain have been further improved with excercise.I used to go to the gym 5 days a week, but since my injuries i slowed down, and become progressively inactive. This i believe lead to weak/loose muscles which just made any joint pain from the Accutane even worse. Im working my fitness level back up and the joints are alot stronger. The processes of jumping, running and applying pressure to them have all improved. I do credit the Hyarulonic Acid supplimentation for getting the joints to a state where i could start working on them. In the future i still need to get my SLAP tear fixed, but its not bothering me too much now.

My hairloss on my head has been rectified with Proscar tablets. One 5mg pill, split into 4, taken every morning. Initial shedding was noted but it has completely stopped and is starting to regrow some hair on my head. No side effects noted luckily, i will continue till it stops working, maybe 3-7 years time. By this time i will most likley be wedded and locked in, so nature may take its course :)

My hairloss in my eyebrows has been reduced since dealing with the seb derm. I still have some limitied hairloss which seems to be in cycles. My dermatolgist analysed my hair and attributes this to chronic telogen effluvium (CTE), due to the bulbous Keratin attached to the end of the hair follicle. I have read many cases in which Accutane users suffer CTE from anywere between 6 months to 6 years, so i am hopefull it will stop on its own one day. I am tossing up wether to use Minoxidal on them until this time comes, however it is a vasodilator so i will do a bit more research before commit.

My dry eyes have not been giving me too much trouble latley. I often forget they used to irritate me alot. Again i attribute this success partly to the HLA. A secondary benifit of the HLA is that it smoothened out many of my wrinkles which come from having a dry face. It does not make my face any more moist, hence i still need to use a moisturiser, but it seems to work from the inside out to retain moisture below the skin.

My dermatologist, after i insisted he speak with Roache (accutane makers), has come to the conclusion that my hairloss symptoms were caused by Accutane. At first when i explained to him the studies and made him aware of the side effects which Roache themselves list on there website he still denied it. Now he has a complete turn of mind and the next time i see him he will be documenting my dosage/duration/side effects from Accutane and reporting it to the FDA.

Finally, my Rosacea has been well latley apart from a reaction, in the form of redness, which i had to a new product i tried. I have found the best periods for my Rosacea is when i am using the minimum amount of products. The combination of Elidel (anti-inflammatory) followed by an Aqueous Cream for moisturising has provided the best long term results. I also use Clonodine sporadically when needed.

Again i really believe that Accutane and to a lesser extent high doses of Vitamin A, while they may provide marked improvements in some symptoms, should be used as a very last line of therapy. I would gladly be sitting here with acne than the other things i have had to deal with.

Anyone that wants more information on Accutane and its side effects is more than welcome to ask me here or private message me.

Regards,

Mike
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby CrabbyCathy » Wed Jul 14, 2010 10:42 pm

Hello!

Trying to go through all posts to find the answer, but this might be easier! How much hyaluronic acid are you taking? And it's pure HA? The only Doctor's Best I can find online (unless my Google is broken) has chondroitin added.
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Please note: Any advice offered here is not meant to replace medical advice. Always see your dermatologist.
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby Mike T » Thu Jul 15, 2010 10:20 am

No, your Google is working fine (yes)

There are 3 types of HLA.

High, medium and low molecular weight. All 3 can be produced outside of the body.

The HLA produced by our bodies to lubricate our joints is high molecular weight. Many hundreds of thousands of Daltons.

High molecular weight HLA is 100% HLA produced through synthetic means. It is most commonly used for intercranial injections into joints. It is not suitable for oral indigestion due to its high molecular weight and thus low penetrative ability.

Medium molecular weight HLA is also not suitable for indigestion.

Low molecular weight HLA is sourced mainly from chicken stern cartlidge. By boiling up the cartlidge and extracting the minerals you are left with 3 components in the following standardised amounts; 10% HLA, 20% Chrondroitin Sulfate and 60% Collagen Type 11.

This low molecular weight product (which should really be named Collagen as this is the main mineral) is able to easily penetrate the stomach linings and make its way to the epidermal layer, something high molecular oral HLA can not do effectively. Basically low molecular HLA provides greater epidermal benifits than joint lubrication, while high molecular HLA is the opposite.

When i started the suppliment i took 2 per day (am/pm). After a few weeks i cut back to one per day with sustained benifits. I really noticed the difference in my face texture within 2 weeks. When i laugh i used to have a fair bit of wrinkles due to the dryness of my face, now most wrinkles have evened out and my face looks more full so to speak. The dryness of my face however has not changed. It seems to maintain moisture from the inside out not the other way round.
Also some minor benifits have been noted in joint clicking and pain.

the older you get the less HLA your body produces. The suggested dosage is 2 tablets per day on my container, however i dropped back to one because my body would still be producing some its own.

Each pill contains 50mg HLA, 100mg Chron sulfate and 300mg Collagen Type 11.

I would recommend it based on my experience. However i believe i have lower than normal production of natural HLA in my body due to Accutane side effects which is why i may see the benifits greater than someone with standard levels of HLA production.

Regards,

Mike
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby CrabbyCathy » Mon Jul 19, 2010 8:52 pm

Thank you for all that information! :) Now I know what to look for. I happened to grab Solaray Triple Strength Hyaluronic Acid while at Whole Foods a few weeks ago, before thinking to research here what you were taking. There are only 30 tablets, so I should be done with them fairly quickly, and then I can try the other brand.
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Please note: Any advice offered here is not meant to replace medical advice. Always see your dermatologist.
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby Mike T » Thu Jul 22, 2010 4:07 pm

Cool.

Let me know how it goes.

You should start to see a difference at about the 1-2 week mark.

Remember HLA helps to retain water. You still need to drink adequate amounts. I try for atleast 1 litre/day.

Mike
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby johnniehaz » Fri Jul 30, 2010 11:15 am

Hello
God, it's good to find people who seem to be able to do something about the effects of Roaccutane on their bodies. All I've been able to find are horror stories.
I have suffered mentally from the effects of Roaccutane since 1987. It came on within months of taking the drug. It has only recently been confirmed that it is actually the Roaccutane that did it. My symptoms have been odd and hard to describe, but are mostly anxiety related. I saw a doctor this week who asked me within 5 minutes if I'd ever taken Roaccutane, and she dropped the bombshell. The thought that my brain/self/consciousness is affected is profoundly distressing.
Anyway - are you able to point me in any directions that may provide some hope for turning this thing round? Do you know of any doctors specialising in it? Are the supplements you are using for general use, or just good for joints etc?
Thanks
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Re: The case against Accutane / isotretinoin (AKA. Poison)

Postby Mike T » Fri Jul 30, 2010 11:57 am

Hi Johnie,

first of all i would like to point out that you are definetley not alone.

I have read tens, if not hundreds of similar stories to your own, from one website alone.

It seems to me that alot of people either suffer physical or mental side effects. Some however suffer both. Although I do not suffer (as far as I know) mental side effects I can imagine it would be particularily distressing.

It is true Rooccutane has been linked to depression, anxiety and suicidal tendincies in some of it's users due to an effect it has on a certain part of the brain.

While I mostly focused on information which concerned my side effects I came across many people who suffered side effects similar to yours. The good news is I recall many of them being Blento overcome the mental issues brought upon by Accutane.

In one case a certain individual who had really frightening nightmares every night since taking accutane, and was in deep depression, found complete clearance of symptoms after taking a certain medication.

The website which has taught me the most about accutane side effects is listed at the top of my original post in this thread. I highly reccomend you take a look at it. There are many threads and may take a while to find the relevant ones but it's worth it. A usefull thread is named "accutane method of action explained". I would start from the most recent posts in the threads and work back.

You will come across a poster named NCC or The Insider. He is one of the most versed persons you will meet in relation to accutane and it's side effects. He is a sufferer himself. He has written a report on Accutane and it's side effects, in which a large part deals with the mental side effects and how Roache tried to cover this up. Treatments are also discussed. I am not sure if it is sti free but if not I have a copy and can send to your email. I highly reccomend reading it. I also have contacted NCC via email. He is very helpfull and will answer any questions you have including treatment suggestions.

All of the above information and contact details can be found by reading through the threads on the first website linked in the first most post.

I am very confident that you will find usefull information in the site I mentioned. It will take a few days research but it's worth it.

Let me know how it goes.

I will have a look for you as well and post back here if I find anything relevant.

All the best

Mike
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