A recently published paper that seeks to compare the actions of oxymetazoline (Rhofade) and brimonidine (Mirvaso) has raised a possible safety issue with the action of oxymetazoline. The paper states the safety issue as; As the 5-HT2B receptor is potentially involved in drug-induced valvulopathy, the benefit/risk ratio (of Rhofade ed.) should be carefully considered, especially in […]
Thanks to an educational supplement in DermatologyTimes, we have access to 5 expert rosacea tips, or as they are called “treatment pearls”. Make sure to treat the skin barrier before initiating drug treatment. Patients need to avoid the use of alcohol-based products, as well as harmful soaps or toners, and focus on appropriate use of […]
Described in the official trial only as a “topical cream”, Sol-Gel are undergoing a Phase 3 trial for a product newly designated as S5G4T-1. What is S5G4T-1? (Now Epsolay) Although the clinical trial listing doesn’t provide any details about the components of S5G4T-1, their own web site reveals more information. Based on Sol-Gel’s product portfolio, it seems […]
Allergan is sponsoring a clinical trial to evaluate whether their oxymetazoline HCL 1% based treatment – Rhofade, is an effective adjunctive treatment for rosacea patients undergoing treatments with Pulse Dye Laser (PDL), Intense Pulsed Light (IPL) or KTP Laser. The trial is designated as a Safety and Tolerability measure, so researchers will be looking for […]
This just published article is describing some clinical work has been concluded that proposes using topical Ivermectin (Soolantra) to treat ocular rosacea. Soolantra so far has only been approved as a treatment for the papules and pustules of rosacea. Soolantra is thought to be effective against rosacea because of its anti-demodex and anti-inflammatory properties. […]
