Recent Rosacea Blog Posts

This just published abstract is looking at recent advances in the use of the tetracycline family in treating rosacea. Of course a lot of the interest in subantimicrobial dose doxycyline has been motivated by the introduction of the Oracea to the market. A previous published study instigated by Collagenex (now owned by Galderma) showed that […]

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Reading this just published abstract highlights for me just how slowly indeed research moves along. These recently proposed methods of action of tetracyclines seem to embody far from ground breaking research. We learnt in 2007 that tetracyclines have anti-inflammatory actions:  “Tetracyclines are known to exhibit multiple significant anti-inflammatory actions … the mechanisms of this anti-inflammatory […]

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Doryx + Applesauce, for Those Who Can’t Swallow Tablets

If you have trouble swallowing tablets, here is an official FDA sanctioned tip. Open the tablet and sprinkle the delayed release pellets on to a spoonful of applesauce. This is a good option for anyone who finds swallowing the capsule difficult. This advice is only given for the 100mg and 75mg delayed release formulations of […]

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Is Oracea different to 50mg a day of Doxycycline ?

I came across the following graph in a recent presentation at the recent AAD meeting and figured it was interesting enough to highlight it here. The following graph, sourced from Collagenex (who sell Oracea), shows the blood plasma concentration of doxycycline after taking Oracea compared to 50mg once a day of generic doxycycline. The horizontal […]

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Oracea Too Expensive ?

Some interesting comments from KUNC commentator Dr. Marc Ringel via a NPR segment. He raises two points that are worth discussing. Firstly is Oracea really any better than generic doxycycline and secondly what does it say about the pharmaceutical industry (and insurance companies – ed) that a repackaged old product  can be so expensive ? […]

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