tetracyclines

Recent Rosacea Blog Posts

DFD-29 on it’s way, now has an NDA

Journey Medical’s modified released 40mg minocycline (still code named DFD-29) has published positive Phase 3 Clinical Trial data and is now sitting waiting on a New Drug Application. The company press release touts the combination treatment for both the inflammatory lesions and the redness of rosacea. By comparison, Oracea, the competing product that DFD-29 claims […]

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Minolira for the treatment of rosacea

In 2017, the FDA approved the extended release formulation of minocycline, known as Minolira, for the treatment of severe acne vulgaris. The modified release formulation of doxycycline known as Oracea, was approved for the treatment of rosacea in 2006. As minocycline and doxycycline are related tetracyclines, Minolira may offer rosacea sufferers another rosacea treatment option, […]

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Hydroxychloroquine works same as doxycycline for rosacea

A pre-proof version of an article to appear in the Journal of the American Academy of Dermatology details a small double blind study that found that oral hydroxychloroquine 200mg twice a day offered similar benefits to rosacea sufferers compared to doxycycline 100mg a day. Hydroxycholorquine (HCQ) is marketed under the name Plaquenil and is best […]

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Hovione Trialing topical HY01 Minocycline Gel

In a crowded rosacea topical market, Hovione is trialing a new topical antibiotic formulation – 1% vs. 3% minocycline gel. HY01 is said to be based on a “proprietary formulation of crystalline minocycline base and oil-based excipients.” In the topical anti-papule and pustule market, this new formulation of Minocycline is up against the industry heavyweights […]

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Sarecycline for acne and rosacea

I don’t know if rosacea sufferers really need another tetracycline variant, but Allergan has published some promising Phase III trial data for Sarecycline as a treatment for the lesions of moderate to severe acne. Whilst no longer being directly promoted as a treatment for rosacea (and indeed it is not clear if Allergan will be […]

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