Oxymetazoline

Oxymetazoline is one of the treatments to watch in the next couple of years. Oxymetazoline is at a high level similar to Mirvaso but is being progressed through clinical trials by Allergan under the name AGN 199201. This product was previously known as V-101 when it belonged to Vicept.

Recent Rosacea Blog Posts

Allergan – Rhofade has no rebound

In a document prepared for Allergan’s November 4, 2015 R&D Day presentation, Allergan is highlighting the development of its soon to be approved oxymetazoline 1% cream for rosacea. The slides relating to Oxymetazoline show the features of this product, along with other products in development, that Allergan wants to promote to investors. In the presentation […]

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Allergan’s Oxymetazoline gentler than Mirvaso

Two small updates on the progress of topical oxymetazoline towards being available as another treatment for the redness of rosacea. The update tells us firstly that Allergan’s Oxymetazoline based product is in indeed in the final stages of approval, having completed Phase 3 trials and been submitted to the FDA for final approval. Secondly the […]

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Rhofade – Allergan’s oxymetazoline brand name

Allergan haven’t announced it yet, but it seems pretty clear that they are planning to use the brand name Azultro for their oxymetazoline based treatment for the erythema of rosacea. Azultro started life as V-101 when owned by Vicept Therapeutics. It was renamed as AGN-199201 after Allergan purchased Vicept. Actavis now owns Allergan. I had […]

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Allergan’s Oxymetazoline Starts Phase 3 Trials for Redness

Allergan have listed their Phase 3 trials details for AGN-199201, their Oxymetazoline based treatment, called AGN-199201, for the persistent red face associated with rosacea. Phase 3 trials like this one are interested in assessing the safety and efficacy of the active ingredient in a proposed treatment. Efficacy is proved by comparing the active treatment against […]

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Afrin (Oxymetazoline) Safe Off Label Drug for a Red Face

This paper from Hospital Pharmacy is giving a guarded approval for the use of Oxymetazoline topically for the redness of rosacea. Even though the FDA has not approved Oxymetazoline as a topical skin treatment, it is approved as a nasal decongestant. Doctors are able to prescribe drugs for off-label use, that is once a drug […]

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