Hovione – Topical Minocycline Gel starts Phase 3 testing

Promoted as being safer than systemic antibiotics, a 3% formulation of topical minocycline gel has passed Phase 2 clinical trials and is readying to commence Phase 3 trials. The owners of the product, currently named HY-01 – Hovione are promoting their in-development topical as more moisturising than other comparable topicals, and less likely to induce […]

What’s new for rosacea treatment?

If, like me, you see a published article titled `What’s new for rosacea treatment’ and get a small rush thinking there must be something new about to burst on to the market, then maybe you might share my disappointment. All regular readers of this web site will know the latest and greatest information about the […]

Epsolay is Sol-Gel’s Benzoyl Peroxide for Rosacea

A new treatment for the papules and pustules of rosacea has been given its product name. Publicity surrounding the trial of the new benzoyl peroxide based rosacea topical has mentioned that the product is to be called Epsolay. Previously Epsolay has been known as VERED, S5G4T-1 and DER 45 EV. It is encouraging that Epsolay has […]

Sol-Gel’s S5G4T-1 (Epsolay) benzoyl peroxide cream for papules and pustules

Described in the official trial only as a “topical cream”, Sol-Gel are undergoing a Phase 3 trial for a product newly designated as S5G4T-1. What is S5G4T-1? (Now Epsolay) Although the clinical trial listing doesn’t provide any details about the components of S5G4T-1, their own web site reveals more information. Based on Sol-Gel’s product portfolio, it seems […]

Sarecycline for acne and rosacea

I don’t know if rosacea sufferers really need another tetracycline variant, but Allergan has published some promising Phase III trial data for Sarecycline as a treatment for the lesions of moderate to severe acne. Whilst no longer being directly promoted as a treatment for rosacea (and indeed it is not clear if Allergan will be […]