Metrogel 1%
Long considered to be the main standard topical treatment for rosacea, Metrogel 1% is the Galderma branded treatment that contains 1% of Metronidazole. Over the years Galderma has brought us Metrogel 0.75%, Metrolotion, Metrocream and now Metrogel 1% Pump 55gm.
Be sure to check out the Metrogel 1% User Reviews and How does Metrogel work?.
Recent Rosacea Blog Posts

This paper found that 0.75% metrogel worked just as well as ketoconazole 2% cream in treating SD. The study found that both were able to offer significant improvement with similar side effects. The authors suggest that because there is so little evidence of anti fungal activity of metronidazole, it is difficult to speculate that this […]
Collagenex is set to become a subsidiary of the much bigger Galderma, after CollaGenex agreed to a merger. So 2 of the biggest pharmaceutical companies involved with make rosacea treatments are to become the same company. Galderma has long been associated with rosacea treatment, and is best known for the metronidazole based topicals metrogel, metrocream […]
Another recently published paper that seeks to understand the role of Reactive Oxygen Species in the development of rosacea. The inflammatory pathway that leads to rosacea symptoms is slowly gaining more and more attention. All rosacea sufferers should do themselves a favor and do some reading on the role of inflammation in rosacea. This is […]
A clinical trial, sponsored by CollaGenex, is recruiting patients to see how Oracea compares to doxycycline (100mg once a day) when combined with metrogel 1%. We can see from a Collagenex annual report that COL-101 was the name for Periostat MR, which then became Oracea. Safety and Efficacy Study to Compare Two Rosacea Treatment Regimens Purpose: To compare […]
Two recently published papers look at the processes involved when you apply metrogel topically. The first abstract just tells us that they undertook some new ways of measuring metronidazole absorption, but doesn’t reveal their results. The second abstract suggests that a cream based metronidazole formulation (presumably metrocream, but could also include Noritate) had the greatest […]