Epsolay is Sol-Gel’s Benzoyl Peroxide for the papules and pustules of Rosacea. Epsolay is a topical microencapsulated 5% benzoyl peroxide cream. Sol-Gel encapsulate the benzoyl peroxide in porous silica microcapsules, claiming that this increases drug delivery time and reduces possible irritations.

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Epsolay is on its way, will it stay?

The benzoyl peroxide based Epsolay is one step closer to becoming a new treatment for the papules and pustules of rosacea. Based on an active ingredient of 5% bezoyl peroxide, and encapsulating inside silica, the new cream has continued to be tested and now Phase 3 results have been published. So what do the Phase […]

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Epsolay is Sol-Gel’s Benzoyl Peroxide for Rosacea

A new treatment for the papules and pustules of rosacea has been given its product name. Publicity surrounding the trial of the new benzoyl peroxide based rosacea topical has mentioned that the product is to be called Epsolay. Previously Epsolay has been known as VERED, S5G4T-1 and DER 45 EV. It is encouraging that Epsolay has […]

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Sol-Gel’s S5G4T-1 (Epsolay) benzoyl peroxide cream for papules and pustules

Described in the official trial only as a “topical cream”, Sol-Gel are undergoing a Phase 3 trial for a product newly designated as S5G4T-1. What is S5G4T-1? (Now Epsolay) Although the clinical trial listing doesn’t provide any details about the components of S5G4T-1, their own web site reveals more information. Based on Sol-Gel’s product portfolio, it seems […]

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Sol-Gel Releases E-BPO Phase 2 Trial Notes

In July 2009 we learned that Ness Ziona, Israel based Sol-Gel was trialing a supposed Benzoyl Peroxide derivate DER 45 EV for the treatment of rosacea. Sol-Gel was granted Investigational New Drug Application for DER45-EV in November 2009, which allowed Sol-Gel to undertake Phase 2 Trials. DER45-EV has been licensed to a US based Pharmaceutical […]

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Sol-Gel Trialling Benzoyl Peroxide (DER 45 EV, Epsolay) for Rosacea

An intriguing Clinical Trial has been listed on the ClinicalTrials.gov web site. The product know only as DER 45 EV Gel (in strengths of 1% and 5%) has been listed in a dose-range trial for the papules and pustules of rosacea. Clinical Trial NCT00940992, A Dose-Range of DER 45-EV in Treatment of Rosacea (SGT-EBPO1-09) To […]

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