Demodex Mites

Demodex Mites and rosacea are often talked about together, but so far its has proven difficult to prove that the mites cause rosacea symptoms. The best we know so far is that a bacteria associated with the mites, known as B. oleronius, has been shown to induce an immune response in rosacea sufferers. Collected here are the most relevant articles that attempt to tie down just what role demodex mites play in the development of rosacea.

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Demodex Bacteria Protein Response Isolated

Hot on the heels of a paper detailing the fact that demodex bacteria-based proteins inhibit corneal wound recovery, is this paper consolidating a direct relationship between an immune response and facial and ocular rosacea. Recent research from 2007 has isolated 2 proteins from the bacteria from Bacillus oleronius, that stimulate inflammatory cells in rosacea sufferers. Proteins […]

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Counting Demodex Mites with  a Confocal Laser Microscope

This paper describes a new way of counting facial demodex mites. A type of microscope called a Confocal Laser Scanning Microscope was used to look for `roundish or lengthy cone-shaped structures’ on the skin, and these were counted as demodex mites. This type of approach is less invasive than a scraping or biopsy. Thus rosacea […]

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This just published abstract takes the demodex bacteria based irritation line of research a step further. Researchers in Ireland were able to show that demodex bacteria Bacillus oleronius proteins induced an “aberrant wound healing response” in  the cells irritated by scratch in a cornea. The aberration appeared as an elevated immune response and an chagnes […]

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Ocular Rosacea Video Worth a Watch

Thanks to a tip from Dori, on the Rosacea Support Group Email Group, here is a link to a video of a lecture giving a good overview of ocular rosacea and treatments. Ocular Rosacea: Curse of the Celts and Celebs The presentation is given by Heather Potter, MD, an Ophthalmologist from the University of Wisconsin […]

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An update to the 2009 filing of the patent covering preparations of Ivermectin and Metronidazole has emerged at the USPTO Patent Application Site. That application was in turn a followup to the original French language application 0505918 from 2005. The patent covers many different combinations of ivermectin and metronidazole such as emulsion, cream, gel with […]

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