This article, just published is adding to body of research of the anti-inflammatory actions of the tetracycline family. Recent related studies have been undertaken during the development of low dose doxycycline, for eg. oracea. So far this abstract isn’t teasing us with anything new. A similarly titled paper from 2006, Tetracyclines: their non-antibiotic properties also addressed this topic.
Anti-Inflammatory Activity of Tetracyclines, Dermatol Clin. 2007 Apr; 25(2):133-135, Webster G, Del Rosso JQ.
Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as acne vulgaris, rosacea, bullous dermatoses, granulomatous disease, and livedo vasculitis.
Further Reading ;
- Subantimicrobial Dose Doxycycline for Acne and Rosacea
- Tetracyclines: their non-antibiotic properties
- Periostat (doxycycline) goes generic, get ready for Oracea
- low dose doxycycline hyclate (SDD)
- incyclinide targets conditions other than rosacea
- Rosacea Support Resource Pages: Antibiotics & Anti-Inflammatories