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In a document prepared for Allergan’s November 4, 2015 R&D Day presentation, Allergan is highlighting the development of its soon to be approved oxymetazoline 1% cream for rosacea. The slides relating to Oxymetazoline show the features of this product, along with other products in development, that Allergan wants to promote to investors.
In the presentation Allergan makes claims that their oxymetazoline based product is superior to Mirvaso in a few ways;
- less adverse events
- no rebound redness
- better safety profile
- lower discontinuation after 1 year’s use
In other publicity Allergan has further distanced Oxymetazoline from Mirvaso, perhaps wanting to show that oxymetazoline might be a better tolerated topical treatment for the red face experienced by rosacea sufferers.
Favorable Safety Profile
The first slide for Oxymetazoline highlights the “Favorable dermal safety compared to Mirvaso”.
High Satisfaction
The second Oxymetazoline slide highlighted the number of patients who reported being satisfied or very satisfied on day 29.
Fewer Adverse Events than Mirvaso – No Rebound!
The third slide is the most interesting with Allergan claiming that their Oxymetazoline 1% Cream (likely to be called Azultro) has a better adverse event profile compared to Mirvaso, as well as a lower rate of discontinuation after 1 year of use.
The slide is also claiming that Allergan’s 1% Oxymetazoline cream has no rebound effect. This sounds like great news, as long as it is found to be correct of course.
Full Press Release
The 2015 R&D Day PDF was made available via phx.corporate-ir.net – R&D Day Presentation (linked off the Allergan R&D Page). Normally these sorts of `forward looking’ presentations are full of disclaimers and legal statements, but this document doesn’t contain any. It would appear that Allergan are going all out, a year from availability, starting their marketing push for Azultro.
Related Articles
- Oxymetazoline 1% Cream for 1H 2017
- Azultro – Allergan’s oxymetazoline brand name
- Waiting for Azultro, Afrin users beware
- Oxymetazoline: what about rebound redness ?
- Allergan’s Oxymetazoline gentler than Mirvaso
- Oxymetazoline good for 6 hours and safe for 3 months
- How to Cure a Red Face (Facial Erythema)
- Mirvaso User Reviews
Ok that’s all good news but what about cost? anyone have a clue? Soolantra just jumped to $100.00 a tube for me even with coupon, was $25.00 last month. I’ll bet it’s up there unfortunately.
It won’t be cheap by any measure of cheap – you are right there. Unfortunately the bigpharma companies want good returns on their multi million dollar investments in new treatments.
So when will I be able to have it in hand?
Be EXTREMELY careful with this medicine. I had minor redness of the face after taking accutane for 6 months. My doctor gave me Rhofade all nonshalantly. I began to use it once a day everyday for a few months. Well slowly I realized it was actually making my face more red. When I would not put it on, my face would be bright red, making me look ten times worse. I have completely stopped taking it now for about a month and my face is still very red. My doctor prescribed me doxycycline to help get rid of the redness but it is not working good. Does anyone have any suggestions? I would rather take a pill instead of a topical at this point. I tried propranolol but it made me dizzy and light headed. Please, anything would help I am desperate!