Archive for September, 2005

Recent Rosacea Blog Posts

Zileuton, an Oral 5-Lipoxygenase Inhibitor, Directly Reduces Sebum Production, Dermatology 2005;210:36-38 Background: Zileuton, a 5-lipoxygenase inhibitor, reduces the number of inflammatory lesions in moderate acne and inhibits the synthesis of sebaceous lipids. Objective: To detect whether zileuton directly reduces sebum synthesis. Methods: A 40-year-old female with mild disseminated sebaceous gland hyperplasia and seborrhea was treated with […]

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Gentle Cleanser is Important

This one of the simple but powerful things to learn about treating rosacea. A gentle and mild cleansing regime is important. Add a gentle moisturizer and a physical sunscreen and you have the basis to build on to treat your rosacea. The inflammation you see in rosacea can be helped just be be gentle with […]

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Ocular Rosacea in Children

Written by on September 28, 2005 in Ocular Rosacea with 7 Comments

According to this paper, ocular rosacea in children may be misdiagnosed as being viral or bacterial in origin. The clue of skin involvement (ie. rosacea papules and pustules on the face) is often missing in children, making the correct ocular rosacea diagnosis more difficult. Thankfully children do seem to respond to conventional ocular rosacea treatments, […]

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Human genome screen to identify the genetic basis of the anti-inflammatory effects of Boswellia in microvascular endothelial cells. DNA and Cell Biology, Apr 2005, Vol. 24, No. 4: 244-255 Abstract: Inflammatory disorders represent a substantial health problem. Medicinal plants belonging to the Burseraceae family, including Boswellia, are especially known for their anti-inflammatory properties. The gum […]

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Incyclinide phase 2 for acne

Written by on September 27, 2005 in tetracyclines with 0 Comments

Formerly known as COL-3, Incyclinide will start a new Phase 2, double-blinded, placebo-controlled trial to find the best treatment dose. This trial will evaluate 300 patients for moderate to severe acne. A recent Phase 2 Clinical Trial showed some promise for inflammatory lesions in rosacea. Incyclinide is a chemically modified tetracycline, modified to retain non-antibiotic […]

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