A clinical trial to determine whether Restasis (topical cyclosporin) is effective in the treatment of ocular rosacea is currently recruiting patients. The study is designed to compare the `efficacy of topical cyclosporin (Restasis) with that of Refresh Endura for the treatment of the signs and symptoms of ocular rosacea in patients presently controlled on topical corticosteroids’.
The Inclusion criteria ;
Pt at least 18 yrs but younger than 65 Diagnosis of acne rosacea active ocular rosacea based on lid findings of meibomian gland dysfunction with lid telangectasia and hyperemia of at least 2+ Schirmers test of greater than 5mm in at least 1 eye If patient currently using lid hygiene must maintain regimen during study Stop oral antibiotics at least 4 weeks prio
Interestingly the exclusion criteria includes “Flax seed or Fish oil supplements within last 30 days”.
Clinical Trial NCT00348335: Efficacy of Topical Cyclosporin for Ocular Rosacea.
- Wikipedia: Cyclosporine
- What Is Restasis And How Does It Work?
- Refresh Endura
- Rosacea News: ocular rosacea in children
- Rosacea News: ocular rosacea treatment and pathogenesis
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- Rosacea News: ocular rosacea questions answered (Part II)
- Rosacea News: ocular rosacea questions answered (Part I)
- Rosacea News: treating ocular rosacea (from the AAO)
1 comment so far ↓
I have a severe dry-eye condition and have been diagnosed with ocular rosacea. Currently, my opthamologist is treating me with punctal plugs in both lower puncta, a low dose of Minocycline, and Restasis twice a day. Since the Restasis literature makes it quite clear that Restasis shows no benefit in those with punctal plugs, WHY does my opthamologist continue to insist I continue the Restasis therapy? I have asked him, and he just shrugs off the disclaimer, saying it is not true. If it is not true, why would the drug company that produces Restasis make such a point of including the disclaimer on its own product? What is UP with that? Am I just subsidizing somebody’s big retirement, or what?
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