rosacure helps redness after 1 month

This paper looks to be suggesting that the silymarin/msm containing topical, rosacure/synchrorose was well tolerated and helps with the redness of rosacea. Silibinin (INN) (silybin, Legalon®) is the major active constituent of silymarin, the mixture of flavonolignans extracted from plant Milk thistle. Methylsulfonylmethane (MSM, or dimethylsulfone) is an organic sulfur compound belonging to a class of chemicals known as sulfones.

Rosacure has received only gentle reviews from rosacea sufferers, but as this study was double blind, there may indeed be some small benefits seen as detailed in this study.

Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation, J Cosmet Dermatol. 2008 Mar;7(1):8-14., Berardesca E, Cameli N, Cavallotti C, Levy JL, Piérard GE, de Paoli Ambrosi G. ,San Gallicano Dermatological Institute, Rome, Italy.

Objective: This study aims to evaluate a topical treatment based on silymarin/methylsulfonilmethane (S-MSM) to improve erythematous-telangiectactic rosacea.

Methods: Forty-six patients affected by stage I-III rosacea entered this double-blind, placebo-controlled study. Subjects were treated for 1 month. Clinical and instrumental evaluations were done at baseline, after 10 and 20 days, and at the end of the study. Itching, stinging, erythema, and papules were investigated clinically as well as hydration and erythema instrumentally with capacitance and color measurements.

Results: A statistically significant improvement was observed in many clinical and instrumental parameters investigated (P < 0.001). In particular, improvement of skin redness, papules, itching, hydration, and skin color occurred.

Conclusions: The combination of silymarin and S-MSM can be useful in managing symptoms and condition of rosacea skin, especially in the rosacea subtype 1 erythemato-telangiectatic phase. The action can be considered multicentric and multiphase because of the direct modulating action on cytokines and angiokines normally involved and up-regulated in the case of such skin condition.

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Read more about: moisturizers, red face, topicals