Comments on: Pyratine XR launches, user reviews

By: Kevin

Kevin — Thu, 26 Nov 2009 05:43:18 +0000

I have been using the Pyratine XR twice daily for 8 weeks and thus far haven’t noticed any improvement. I have mild redness but my issue is the break outs of pimples and raised areas and it hasn’t slowed the progression of that at all, if anything it seems just as bad if not worse. I will not buy anymore once my tube is finished. Still looking for something that can help me prevent the breakouts. As I said my redness is the least of my issues, it’s the breakouts. If you know of something better please tell me.

By: Daria

Daria — Mon, 02 Nov 2009 18:51:26 +0000

This stuff does not work. There is a reason there is not a prescription for it. Who has $150 to waste on a product, an itty bitty tube, that makes you REDDER after you wash your face and then the lotion does NOTHING to calm it? None of the doctors I’ve been to even know what Pyratine is. Invest your money in something that’s actually been clinically tested and is FDA approved. You should all feel robbed for this product raising the hopes of people who suffer from the skin disorder in order to make some scam artist’s pockets fatter.

By: David Pascoe

David Pascoe — Wed, 24 Jun 2009 01:42:18 +0000

There are 2 threads in the support community forums that are worth reading ; Pyratine XR is great for me! Pyratine XR--I'm going to be the guinea pig for everyone

By: David Pascoe

David Pascoe — Wed, 24 Jun 2009 01:39:07 +0000

PubMed is now showing the paper mentioned above. Topical PRK 124 (0.125%) lotion for improving the signs and symptoms of rosacea. The conclusion of the paper ; "The new moisturizing lotion containing furfuryl tetrahydropyranyladenine as PRK124 shows a continued trend toward improvement of skin barrier function and the appearances of erythema and papules associated with mild-to-moderate rosacea during 12 weeks of treatment."

By: Erick

Erick — Tue, 23 Jun 2009 17:23:59 +0000

I’m just a regular dude, sports freak surfer in my 40′s who was given some Pyratine XR samples at my dermatologists office.

I do not have rosacea or any real skin problems, other than normal age and maybe sun.

I have been using this stuff on my whole face and neck for a few weeks after shaving, and it seems like my skin is way better, which was totally a surprise.

Maybe it’s just my imagination, but my skin seems to be way smoother, really clear and looks tauter and the lines around my eyes, etc, diminished by about 50%.

Like I said maybe it’s just my imagination, but it sure seems to make my skin look good.

By: queta

queta — Sat, 13 Jun 2009 02:19:28 +0000

I have rosacea quite bad and am using Pyratine XR. It is helping my skin texture and overall blotchiness. I really, really like this product. I know a lot of people are skeptical but for me (mostly phymatous rosacea) it is really helpful. It is expensive but I will continue to use it. I am very happy I found it.
Queta

By: antoinette

antoinette — Sun, 03 May 2009 13:47:51 +0000

I am wrting concerning the effects of Pyratine-6. Last October 2008 I ordered lightening gel and small dose of liquid for a TCA Peel by internet from a reputable company in Detroit. The first 3 weeks my Italian under eye dark circles…gone and then the peel to slough off remaining skin. B Feb. 1st..returned and I was left with dark scars…no hyrdoquinone..s I was surprised and sick that had ruined my skin. I immediately went to a reputable skin specialist in Illinois and she put me on Pyratine-6 and I do not have rosacea. My skin has healed from the burns and now we are working on lightening my skin from the black char scars. I hope that I can help women and men from buying anyting off the internet unless you have a doctors recommendations. The company in Michigan has it’s own estheticians and they are NOT DOCTORS. Your facial skin is what we wear and cannot take off like clothing. I would rather have had a bad haircut..as this has truly thinned out my skin and wrinkled the once tone in my lower eye area. Thank goodness I went to the skin doctor n Lincolnshire Illinois and she put immediately on the road to recovery to skin regeneration and smoothness. We are working on the dark black splotches and pit mark it left (peel and lightener). I wanted Renova..but I was told it would burn more. I am so pleased with my results with no burning and actually my skin after 7 weeks is smooth again. I will never let anyone on the phone tell me how to do any facial treatments as they know best and that doctors are higher price. YOUR FACE AND SKIN…deserve the best. Pyratine-6…you have a real winner and after seeing the softness and smoothness at 56…all ages could benefit from this and never go back to harsh treatments as Retina/Renova/even peels. Darker and olive skin like mne scar and take years to go away or never. Thanks again

By: GJ

GJ — Wed, 29 Apr 2009 12:53:57 +0000

http://www.dermatology.uci.edu/IID%20Senetek%20Poster%20final.pdf

If I was a naughty seller of a topical I would be tempted to suggest that the testee wear lipstick for all ‘after’ shots, to better hide the naughtiness.

By: David Pascoe

David Pascoe — Wed, 29 Apr 2009 01:42:03 +0000

Further, you can see the 2008 paper on the 0.10% formulation at PubMed A clinical study of topical Pyratine 6 for improving the appearance of photodamaged skin. Also see the Clinical Trials register for the 0.125% formulation known as `PRK 124' clinical trial Effects of PRK 124 Lotion in Acne Rosacea. "The purpose of this open-label study is to determine the tolerance and efficacy of twice-daily application of PRK 124 (Pyratine-6)(0.125%) moisturizing lotion for improving the signs and symptoms of mild to moderate facial rosacea."

By: David Pascoe

David Pascoe — Wed, 29 Apr 2009 01:30:54 +0000

Apparently the trial is due to be published in the Journal of Drugs in Dermatology May issue pp 459-462. I can’t see it online yet, but will keep an eye out to see if it becomes easily available for us to read.