Comments on: Oracea to replace Periostat, new rosacea treatment launched http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html Where the rosacea community meets to support each other Fri, 06 Nov 2009 19:38:02 +0800 http://wordpress.org/?v=2.8.5 hourly 1 By: Lori http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-31029 Lori Tue, 27 Oct 2009 02:28:45 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-31029 Dan: Actually I'm not using anything other than the 150 mg of doxy that I've been on all along. I do use the warm compresses as needed and wash my face with Ivory Soap (I've tried others but they are too irritating. Both my dermatologist and eye doctor said there wasn't anything else to treat it...just the warm compresses. I do, however use pretty warm water. It seems to work better than the lukewarm water. I run the water and put a cotton ball under the running water and put it on my eye just til it starts feeling cooler than do it again. I do this about 20 times and then rub with the cotton ball a little and all the white spots are gone. I did have a little tiny scab once doing it this way, but this is working well for now. I don't know if it's the doxy or the almost hot water. I hope you can find the combination that works for you. Hang in there! Dan: Actually I’m not using anything other than the 150 mg of doxy that I’ve been on all along. I do use the warm compresses as needed and wash my face with Ivory Soap (I’ve tried others but they are too irritating. Both my dermatologist and eye doctor said there wasn’t anything else to treat it…just the warm compresses. I do, however use pretty warm water. It seems to work better than the lukewarm water. I run the water and put a cotton ball under the running water and put it on my eye just til it starts feeling cooler than do it again. I do this about 20 times and then rub with the cotton ball a little and all the white spots are gone. I did have a little tiny scab once doing it this way, but this is working well for now. I don’t know if it’s the doxy or the almost hot water. I hope you can find the combination that works for you. Hang in there!

]]> By: Dan http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-31005 Dan Mon, 26 Oct 2009 19:33:55 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-31005 Lori, What did you do to clear up your problem with the oil glands. My doc has got me on 1000mg of tectracycline for 6 weeks along with 2 kinds of drops. I have had flares with the roscea since I switched meds. Am curious what worked for you. Thank you Lori, What did you do to clear up your problem with the oil glands. My doc has got me on 1000mg of tectracycline for 6 weeks along with 2 kinds of drops. I have had flares with the roscea since I switched meds. Am curious what worked for you. Thank you

]]> By: Lori http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-30988 Lori Mon, 26 Oct 2009 16:37:02 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-30988 Hi all: Well the oil gland problem has cleared up pretty well. I still get a spot or two now and then but the warm compress clears it up right away. I make sure to clean my eyelids every time I was my face. I think I'm losing eye lashes more often, but what can I do. The problem now....the Doc has lowered my Doxy from 150 mg timed release to 75 mg with the goal of 50 mg within 3 months. Immediately upon lowering the dose I broke out big time. I went back to the 150 mg for a couple of days and cleared up. Now I'm trying the 75 mg again. I'm feeling pretty miserable about this. What if I can't ever lower the dose? Hi all: Well the oil gland problem has cleared up pretty well. I still get a spot or two now and then but the warm compress clears it up right away. I make sure to clean my eyelids every time I was my face. I think I’m losing eye lashes more often, but what can I do. The problem now….the Doc has lowered my Doxy from 150 mg timed release to 75 mg with the goal of 50 mg within 3 months. Immediately upon lowering the dose I broke out big time. I went back to the 150 mg for a couple of days and cleared up. Now I’m trying the 75 mg again. I’m feeling pretty miserable about this. What if I can’t ever lower the dose?

]]> By: David Paul http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-30959 David Paul Sun, 25 Oct 2009 01:02:50 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-30959 R, Plain english please. - D.P. R,

Plain english please.

- D.P.

]]> By: R http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-30939 R Sat, 24 Oct 2009 07:39:54 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-30939 Hello everyone, good to find this group. Hope my ideas are not that crazy and contribute to alternative cheap ways of treating rosacea. Well, I looked up the plasma concentration curves and interestingly see the 50 mg boost all the way up over the threshold of 1000 mg/mL. 1. So 50 mg generic wil do that and become a problem causing bacteria resistance and side effects so I think 50 mg of Doryx extended release will be a much better bet/option because the release is slowly through the day so I doubt it will ever go over 1000 mg/mL and it seems to be cheaper than doryx. 2. I did some interpolation using the data from the curves graph. A 40 mg generic dose will go up to ~900 mg/mL around 1.5 hr after taking the medication and remain at the top ~900 mg/mL for 3 hrs to start decaying interestingly not lower than the oracea baseline of ~200 mg/mL. Perhaps a higuer baseline is better for inflammation and taking it once a day should be ok. "remember oracea is just like a generic of 30mg once you take it so the 3 hrs of the curve should be similar to a generic 30 mg so the 40 mg would be in between ;) " 3. 20 mg generic doses twice a day should work fine as well, maybe try 20 mg in the morning and then 20 mg during the day with your own extended release method... yes crush it and put it in your water bottle and start drinking it 2-3 hrs after your morning dose so it can keep the does constant. Hope this mathematical scientific method helps... yes try the cheap way and save the $$ away from big pharma brother. cheers Hello everyone, good to find this group. Hope my ideas are not that crazy and contribute to alternative cheap ways of treating rosacea.

Well, I looked up the plasma concentration curves and interestingly see the 50 mg boost all the way up over the threshold of 1000 mg/mL.

1. So 50 mg generic wil do that and become a problem causing bacteria resistance and side effects so I think 50 mg of Doryx extended release will be a much better bet/option because the release is slowly through the day so I doubt it will ever go over 1000 mg/mL and it seems to be cheaper than doryx.

2. I did some interpolation using the data from the curves graph. A 40 mg generic dose will go up to ~900 mg/mL around 1.5 hr after taking the medication and remain at the top ~900 mg/mL for 3 hrs to start decaying interestingly not lower than the oracea baseline of ~200 mg/mL. Perhaps a higuer baseline is better for inflammation and taking it once a day should be ok.

“remember oracea is just like a generic of 30mg once you take it so the 3 hrs of the curve should be similar to a generic 30 mg so the 40 mg would be in between ;) ”

3. 20 mg generic doses twice a day should work fine as well, maybe try 20 mg in the morning and then 20 mg during the day with your own extended release method… yes crush it and put it in your water bottle and start drinking it 2-3 hrs after your morning dose so it can keep the does constant.

Hope this mathematical scientific method helps…

yes try the cheap way and save the $$ away from big pharma brother.

cheers

]]> By: Rhonda http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-30037 Rhonda Mon, 07 Sep 2009 04:23:41 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-30037 Dan and Lori.. Thanks so much for the update and your comments. Because of your update, I understand alot more about the glands in the eyelids, etc. Here is a very nice article that explains alot and makes it pretty clear why the warm compresses work and lid scrubs and antibiotics work. Note the comments about fish and flax oil, too. As to what is causing the problem, well that seems harder to determine, but treatments are pretty clear in this article. I'll put the link at the end of this note. I purchased Tea Tree Oil yesterday and they also had Tea Tree Oil Shampoo and Soap bars, too. The shampoo has peppermint in it. I should be smelling very strange as I try this out. The bar soap was just too stinky and I'm not that desperate yet.. ha. Anyway, I'm going to use a diluted eye lid scrub (keeping it out of the eyes) and see what happens. And I'll try the warm compresses. Looking forward to relieving eye discomfort and fuzzy vision. I'm glad I don't wear contacts with this problem. Ok.. here is very good reading about Meibomitis and/or occular rosacea. Note that if you go to Home page you will see main article on severe dry eye which is more extensive. http://refractiveeyecare.com/v13n3-gilbard.html Dan and Lori.. Thanks so much for the update and your comments. Because of your update, I understand alot more about the glands in the eyelids, etc. Here is a very nice article that explains alot and makes it pretty clear why the warm compresses work and lid scrubs and antibiotics work. Note the comments about fish and flax oil, too.

As to what is causing the problem, well that seems harder to determine, but treatments are pretty clear in this article. I’ll put the link at the end of this note. I purchased Tea Tree Oil yesterday and they also had Tea Tree Oil Shampoo and Soap bars, too. The shampoo has peppermint in it. I should be smelling very strange as I try this out. The bar soap was just too stinky and I’m not that desperate yet.. ha. Anyway, I’m going to use a diluted eye lid scrub (keeping it out of the eyes) and see what happens. And I’ll try the warm compresses. Looking forward to relieving eye discomfort and fuzzy vision. I’m glad I don’t wear contacts with this problem.

Ok.. here is very good reading about Meibomitis and/or occular rosacea. Note that if you go to Home page you will see main article on severe dry eye which is more extensive. http://refractiveeyecare.com/v13n3-gilbard.html

]]> By: Dan http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-30030 Dan Sun, 06 Sep 2009 18:31:46 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-30030 Rhonda, Thank you for the Links. I did see an opthamologist. Turns out that Meibomitis is the cause of the grittiness and blurred vision. I will go on 250mg of tetracycline 4x a day to get it under control. Meibomitis is an infection of the oil glands in the eyes which is commonly associated with ocular rosacea. For all the others who may have this. The Dr. has me doing eye scrubs 2x a day with a cotton swab and warm water and warm compress for 5-10 min, 2x a day. Along with the tetracycline he has prescribed Tobradex eye drops 2x daily and fluorometholone drops 3x a day. This seems to help, the tetracyline needs to be taken up to 3-4 months if I remember correctly and then titered down to manage the condition. Yes,it is getting expensive and Thanks again for the links. My ophthamologist said that there are no over the counter treatments for this. I am not excepting though and will continue to look for otc remedies. Forunately, the tetracycline is not expensive. Rhonda, Thank you for the Links. I did see an opthamologist. Turns out that Meibomitis is the cause of the grittiness and blurred vision. I will go on 250mg of tetracycline 4x a day to get it under control. Meibomitis is an infection of the oil glands in the eyes which is commonly associated with ocular rosacea. For all the others who may have this. The Dr. has me doing eye scrubs 2x a day with a cotton swab and warm water and warm compress for 5-10 min, 2x a day. Along with the tetracycline he has prescribed Tobradex eye drops 2x daily and fluorometholone drops 3x a day. This seems to help, the tetracyline needs to be taken up to 3-4 months if I remember correctly and then titered down to manage the condition. Yes,it is getting expensive and Thanks again for the links. My ophthamologist said that there are no over the counter treatments for this. I am not excepting though and will continue to look for otc remedies. Forunately, the tetracycline is not expensive.

]]> By: Lori http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-3#comment-30024 Lori Sun, 06 Sep 2009 03:48:57 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-30024 Re: Ocular Rosacea Well, guess I have joined the ranks of the sufferers of ocular rosacea. 2 weeks ago I discovered a stye. Well, I have had these before so I didn't get too excited. Then another popped up and another and another, 5 total. I began putting warm compresses on my eyes several times a day. They slowly cleared up. Now I make sure to wash my eyelids carefully twice a day. I do have some grittiness etc but mostly in the evenings when my eyes are tired. The worst part is that I wear contacts and HATE glasses. I'm interested if anyone has tried the tea tree oil treatment. Bet it burns like crazy if it gets in your eyes! If it works on the eyelids, wouldn't it work on the face as well? I am going to the eye doctor soon so I will ask him about this. Re: Ocular Rosacea
Well, guess I have joined the ranks of the sufferers of ocular rosacea. 2 weeks ago I discovered a stye. Well, I have had these before so I didn’t get too excited. Then another popped up and another and another, 5 total. I began putting warm compresses on my eyes several times a day. They slowly cleared up. Now I make sure to wash my eyelids carefully twice a day. I do have some grittiness etc but mostly in the evenings when my eyes are tired. The worst part is that I wear contacts and HATE glasses. I’m interested if anyone has tried the tea tree oil treatment. Bet it burns like crazy if it gets in your eyes! If it works on the eyelids, wouldn’t it work on the face as well? I am going to the eye doctor soon so I will ask him about this.

]]> By: Rhonda http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-2#comment-30022 Rhonda Sat, 05 Sep 2009 22:12:40 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-30022 Dan, Here is another link to occular info. http://rosacea-support.org/treating-ocular-rosacea-from-aao.html (I've listed it at the end of this note) (You might know this already..) There are different kinds of over the counter dry eye drops. I tried a 3 pack of small vials and they were definately different. The one for overnight use had a slight filmy covering and it lasted longer and I'm guess we don't need keen vision while sleeping.. My dreams were a bit foggy however.. lol Anyway, you might might to try other types of drops in smaller sizes. The answer to your question about redness, grittiness, etc. and tea tree oil remedy as posted on the link... is "I don't know". BUT, IF demodex mites in eyelashes are causing inflammatory response in eyes... (thru whatever mechanism) then it appears from other folks here that some forms of tea tree oil treatment on the lids/eyelash might be the ticket for relief. If you can afford it, I still recommend getting to an opthamalogist for accurate diagnosis and possibly prescription medicines. ok.. this link is definately worth reading.. .. as are tons of articles Dave has sorted thru for us... http://rosacea-support.org/treating-ocular-rosacea-from-aao.html Good healing, Rhonda Dan, Here is another link to occular info. http://rosacea-support.org/treating-ocular-rosacea-from-aao.html (I’ve listed it at the end of this note)

(You might know this already..) There are different kinds of over the counter dry eye drops. I tried a 3 pack of small vials and they were definately different. The one for overnight use had a slight filmy covering and it lasted longer and I’m guess we don’t need keen vision while sleeping.. My dreams were a bit foggy however.. lol Anyway, you might might to try other types of drops in smaller sizes.

The answer to your question about redness, grittiness, etc. and tea tree oil remedy as posted on the link… is “I don’t know”. BUT, IF demodex mites in eyelashes are causing inflammatory response in eyes… (thru whatever mechanism) then it appears from other folks here that some forms of tea tree oil treatment on the lids/eyelash might be the ticket for relief. If you can afford it, I still recommend getting to an opthamalogist for accurate diagnosis and possibly prescription medicines.

ok.. this link is definately worth reading.. .. as are tons of articles Dave has sorted thru for us… http://rosacea-support.org/treating-ocular-rosacea-from-aao.html
Good healing, Rhonda

]]> By: David http://rosacea-support.org/periostat-doxycycline-goes-generic-get.html/comment-page-2#comment-29861 David Tue, 25 Aug 2009 20:18:54 +0000 http://rosacea-support.org/periostat-doxycycline-goes-generic-get-ready-for-oracea.html#comment-29861 Hi Rhonda, Thanks for the reply. The answer is no, I have not seen any improvement. I was wondering the same thing, maybe a higher dose would help. I've got an appointment with my derm next week. I hope he will have some ideas about how to improve my situation. Perhaps a higher dose of doxy? I'll report back Hi Rhonda, Thanks for the reply. The answer is no, I have not seen any improvement. I was wondering the same thing, maybe a higher dose would help. I’ve got an appointment with my derm next week. I hope he will have some ideas about how to improve my situation. Perhaps a higher dose of doxy? I’ll report back

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