Mirvaso User Reviews


Mirvaso is so new that only a few rosacea sufferers have been able to try it.

What are your chances of having a bad reaction ?

How are users in the real world faring, and will the general population see the same level of benefits as the large number of Phase III trialists ? So far it seems that many more people are having bad rebound reactions to Mirvaso, compared to the clinical trials.

Well one way that we might get an idea of how Mirvaso is being received is if we can collect reports from people who suffer from redness and try it and give us all some feedback.

Please do leave a comment if you have tried it and have an opinion.

How Well Does Mirvaso Work?

Well your response to Mirvaso is likely to fall into 1 of 4 camps;

  1. For starters, there is going to be a group of rosacea sufferers who won’t be able to use Mirvaso at all because of another condition that is incompatible with Brimonidine.
  2. Some users will get a flush reaction that will probably mean that they will stop using Mirvaso.
  3. Next, there will be a group of rosacea sufferers who get a mild to moderate reaction but will choose to continue to use Mirvaso.
  4. Finally, and hopefully in the majority, will be a group of Mirvaso users who see a good relief in their red face.

Mirvaso Reviews

Alan says:

 Not as impressed as I hoped to be, but only on my 4th day.

dogkrazy says:

I haven’t seen any rebound, but it does wear off. I use it once a day after my shower.

At first, it gets a bit redder looking but a couple hours later it blanches out..rather like pushing your finger hard on something until the pink turns white…it looks tons better!! the less red side almost looks normal on it.

alfypet says:

I tried my Mirvaso today for the first time. I applied about 45 minutes ago. The good news is that I have not reacted badly thus far. I am so used to applying a topical and immediately getting red and flushy, so that is a big plus for me.

The area on which I applied the cream has definitely paled. Surprisingly, this does not necessarily make me look better.

and then;

The good news is that I have used it for three days now and have seen no ill effects. That is huge for me, as I usually react to everything! I can’t use Metrogel, Finacea, Promiseb, Xylogel, etc, without reacting with redness or flushing.

The Mirvaso definitely helps with diffuse redness, and I think a lot of people will have great results. Under my redness, I have visible vessels, which I was hoping would not be visible with Mirvaso. But for me, they are still visible, and no longer hidden by the redness of my overall rosacea. Honestly, had I never had laser treatment and Veinwave, which made these veins more visible, I think I’d have much better results.

I do feel, however, that applying Mirvaso takes down my rosacea, in general, a degree or two. My face feels calmer and less reactive so far. I am at work today, which will be a good test. I usually flush on a daily basis at work at around 6/7 pm. I’m not sure why, but it is probably anxiety trying to finish my deadlines and get out of the office. I’ll see if that happens today.

anon24 says:

Okay I finally picked up Mirvaso from the pharmacy. Using the savings card, I only had to pay $50 for the 30mg tube, and I don’t have a great insurance, so most folks will probably get a pretty good deal on it. I applied it in the parking lot in one spot, ran some errands, and came home, and its now been about 40 minutes. I did about a quarter sized area, and the redness has subsided a bit, but nothing to write home about. I don’t know if it starts to work more after 30 minutes, I assumed that at 30 minutes it was working at maximum ability, but I will post more updates later. It is very easy to apply, spreads very easily (it’s a clear cream, kind of like vaseline), and doesn’t feel drying or anything like that. So the redness is reduced after about 40 minutes, not nearly as much as I’d hoped, but I will update later.

Steven says:

So I got it – about a week ago – used it 4 days – looked great at first, then seemed to have some breakthrough redness before the 12 hours were up. Thought I would stop using it for a few days as I thought I might be developing tolerance to it. The day after I discontinued it my face has been flushed more than before I used it. So rebound redness seems to be potential problem – It certainly has been for me.

wiry says:

Early Review: I tried it on the entire face. I took about 45min-1hr to kick in.

– The forehead results seem to be pretty decent.
– Cheeks were blotchy. Some spots were too pale, which increased contrast from the redder areas.

I think my cheeks looks worse with Mirvaso because it was just too blotchy. Some areas are too pale and unnatural looking. Have you ever heard someone say you look like you’ve seen a ghost? Well, it sort of looks like that. The forehead seemed to give a better cosmetic result. Perhaps with some experimentation one could get it look better. I will try some different approaches and see what happens.

Overall, I think with enough experimentation (and fingers crossed there is no rebound flushing), this could be a useful medication. But I think it will be tricky to really good natural looking results (at least for me). Its a little “black and white” or should I say “red and white”. Maybe if I were to dilute it a little and just go for a toning down of redness, it would be better.

littlelassie says:

This is my third day using Mirvaso and my first day to apply it in the morning instead of the afternoon. Today isn’t the greatest test because I also used little makeup since I was going to be with other people all morning and am a chicken. Interestingly enough I haven’t seen the same degree of effectiveness the past two days, but I believe that’s either because I am using less than the first time or because I have started mixing it with Cerave lotion to help it spread more easily. That being said, my redness has mostly disappeared by 45 minutes after application, I just don’t look freakishly pale. The one thing that bothers me is that at around 5-6 hours I start to see some pink/red coming back. All three days the redness first appears in my t-zone. I think it might have something to do with my skin becoming oily?

Matt_Seattle says:

Test Patch Review:

Well Mirvaso definitely works (at least it did for me). I first applied it just to a section on my nose and it turned it completely pale in that area (took about 20 minutes for the effect). There was no stinging and it applies smoothly (no scent really either) the texture reminds me a bit of cetaphil moisturizer or Cerave PM.. Very thin and easy to absorb. Now after the first application and as others described, it almost looked like an obvious pale spot with surrounding pinkness, but after taking a tiny bit more, working it through the finger tips and lightly applying to the rest of my nose while trying to fade it lightly into my cheeks, it smoothed out and gave a natural pale complexion to my nose. Im pretty impressed with how good it actually works.

Acanthous says:

I used 3 pea-sized blobs for whole face, at 2pm on the day I got the script ($50 w/coupon). I am a flusher, with many, many triggers, including ‘being alive’ and ‘breathing’. Deepest flushing is on nose and cheeks, but rest of face, neck and chest also flush. I always have some redness. Observations:

– I was white like a vampire for approximately 14-15 hrs. Not even red wine and pasta made the treated areas flush.
– this is not as good a look as I imagined it would be. Also, it highlighted the neck and chest flushing I have.
– some normal flushing started coming back on face and cheeks around 8am the next day.
– extreme, weird rebound flushing on cheeks starting by 9 am. Deep, blotchy flush, very hot and uncomfortable.

Renae says:

I have used mirvaso for the past three nights and the results are amazing!!!!!!! The redness/burning/swelling is totally gone! I do look pale in comparison to my normally flush appearance but i couldnt be happier with the results. I’m going to not use it for a few days and see what happens. Has anyone else had the same results as I have?

redman says:

Got it today. Left the Drs office, washed face, applied. 20 minutes later I walk in the house and my wife tells me I look pale. Not pale, I tell her. This is my correct color and that she should try it as well.

Renae says:

I just tried mirvaso and I cannot believe the difference it made with the redness/telangiectasias!!!!! I’ve tried every cream(finacea, metrolotion, oracea etc).

Scotty says:

Hi All – got a sample of Mirvaso yesterday from my Dr.  I used it for the first time this morning after my shower.  Didn’t really think much about it (had little faith to be honest) until I went to the restroom at my office.  Looked in the mirror and was very impressed!  It usually takes a long time for my skin to “settle down” after a shower etc – but my redness was VERY improved!  I still can’t believe the results.  So far I’m a fan.  We’ll see how it goes.  Good luck!

GreenGables says:

Using Mirvaso for 3 weeks. My derm recommended it at my appointment last month. I hadn’t heard of it before. But my derm is fairly on top of new treatments, and she said she’s had positive reports from her other patients since it came out in September.

Maybe that will change the longer I use it, but right now it’s positive for 3 weeks and counting.


I have been using Mirvaso for 3 weeks without any rebound flushing. Of course it all could change at some point, but so far it has worked for me.

Please Leave a Comment

If you have tried Mirvaso, please leave us a comment below so that we can all get to see how well it is going as a treatment – thanks!

Rebound Redness

There is a growing body of reports of bad flushing reactions to Mirvaso. It isn’t yet clear why this is; that it appears that users are having bad reactions to Mirvaso a higher rate than was seen in the Phase 3 long term trials. Take care and work with your doctor if you think you might be worse off after using Mirvaso.

So please do let us know in the comments below whether you stick with Mirvaso or have to stop using it.

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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638 Reader Comments

  1. CathySullivan says:

    I have used this product for four days and found some relief ( I had a mild case). On the fifth day I experieced flushing which I have never experience before. I stopped using the product for two days and I am still experiencing extreme rebound flushing. The flushing and redness is worse than before, and so very uncomfortable! I put on hyrdrocortisone cream 1%, a cool beverage, and a fan on my face seems to help a bit.
    Tomorrow, I will be calling my derm and tell him not to prescribe this medication to those who have very fair and sensitive skin.
    I do hope the flush will go away, and not damage my skin permanently.

    • jenifer says:

      Hello, I wanted to see if you were able to recover from your usage of the Mirvaso cream. I am suffering myself now and wanted to see if there are any results or hope of getting better and I hope you have

  2. Florinda says:

    I’ve been on Mirvaso for about a month now. I don’t seem to have a reaction to it when I don’t use it. It does help with the swelling, redness and acne like breakouts. The breakouts disappear when I use it. I use it in the morning and it lasts about 10 hours. I’m also using Zyxal for the itching but even the itching goes away when I use Mirvaso. I will continue to use Mirvaso. I’ll write an update in about a month to see if Mirvaso is still working.

    • Ann Halpin says:

      I’ve been using Mirvaso for the past five months and as long as I use a pea sized amount for my entire face it works great. I am having an outbreak at the moment but that is due to stress and and eating two trigger foods (my fault). I think for those for whom it doesn’t work there are other options. I had tried Metrogel and Finecia first. Metrogel didn’t completely work and the Finecia completely burnt my skin. We just all have to find what works for our own skin.

  3. xdhzx says:

    Made redness and flushing so much worse from the start! Initially it took a little redness away for maybe an hour or so then came the worst flushing, blotchy skin and redness I have had in years. I thought maybe my skin needed to get used to it. I mixed it with moisturizer and sunscreen that I tolerate very welll as other had suggested but everything became a trigger and sent my face, neck and chest into such horrible flushing I had to leave work more than once. I’ve stopped using it for three days and it’s still happening. I know my face is more red because I did take photos. Mirvaso was a complete failure for me. I’ve made and appointment to have V-beam laser treatment in hopes of reversing the damage.

    • jenifer says:

      Hello, I wanted to see if you were able to recover from your usage of the Mirvaso cream. I am suffering myself now and wanted to see if there are any results or hope of getting better and I hope you have

  4. Mark says:

    I have used Mirvaso for 6 days now. The first 4 days were great I could not believe how it reduced my redness, and the gel lasted nearly 12 hours. Now the last 2 days have been a nightmare, 10 hours in and my face started burning like fire. The worst thing about it was I was at work whilst it happened. I went for a walk outside to try and cool down, but soon as I stepped back in work I was burning up dark red. Then my workmates were looking at me which made it even worse. I just wanted to run and hide but I had to keep my machine at work running. The flushing lasted over 3 hours, then calmed down. I had never had flushing like this before I had started on the Mirvaso gel. So as from now I am not using it any more. I just wanted to share this to make others aware what this could do to you. I was just so fed up with my Rosacea that I had to try it. But please be careful and think about the rebound flushes before you start using it.

    • Jenifer says:

      Hello, I wanted to see if you were able to recover from your usage of the Mirvaso cream. I am suffering myself now and wanted to see if there are any results or hope of getting better and I hope you have

      • Jen says:

        Hello, I wanted to see if you were able to recover from your usage of the Mirvaso cream. I am suffering myself now and wanted to see if there are any results or hope of getting better and I hope you have

    • Erika says:

      I had the same problem this past week. I was at work and my face turned BRIGHT red and was hot, almost as if I had the worst sunburn possibly. It was an awful experience. I have been OFF of Mirvaso for about 3 days and my face is still bright red, not as hot though. Never using this stuff again. Horrible experience.

  5. Jay says:

    The first 2 days Mirvaso worked just fine, but then it just made my face worse! It completely changed my life, I just wish I had never started using it.
    When I put it on, the redness slightly decreases as Mirvaso is fresh, but it only lasts 30 minutes or less! If I go into a place, for example a classroom (I’m a 18 year old teenager, I’m still studying), my face just starts burning like hell, just like Mark said above, my face turns dark red, like a tomato… I can’t ask to go outside to get some air or anything and schools are full of people, it’s so uncomfortable. I can’t stop thinking about it which makes it even worse. The flushing, redness, burning sensation have gotten really worse since I started using Mirvaso.

    • Arthur. says:

      I think 95% of folks who have used Mirvaso have had very bad reactions , me included . I was very excited when I first applied Mirvaso , then two hours later my face looking like a Stop light . If only galderma could sort out this rebound Flushing thing , but until then I will NOT be putting their Mirvaso anywhere near my skin and I would advise anyone who has thought about trying it …DON,T !!!!

      • Stuart says:

        Thanks Arthur and Jay. My feelings exactly. In fact, after I reported in to my doctor, he told me to throw away all the samples he had given me

        • Jay says:

          I’m just afraid of stop using it, that’s why I haven’t yet. I think it has a ”psychological impact” or so, at least, once I put it on I just think ”Ok, I have Mirvaso on, there’s nothing I should worry about” but then my face just turns hot and it feels like I’m in hell.
          I’m trying to convince my mom to take me to see my derm again as it’s kind of expensive… otherwise I’ll just stop using it during winter break.

      • Mike says:

        I’ve been using Mirvaso for about 6 weeks now. For the first 5 weeks it worked very well but over the last 7 days I’ve been having horrible rebound effects and flushing. Face as red as a tomato and a horrible burning sensation. I’ve never had this experience before using Mirvaso. I’m going to stop using it completely as of today.

        • jen says:

          Hello, I wanted to see if you were able to recover from your usage of the Mirvaso cream. I am suffering myself now and wanted to see if there are any results or hope of getting better and I hope you have

  6. Sarah Jane Dawson says:

    I absolutely couldn’t wait to start using my Mirvaso cream and was totally buzzing as it began to work on day one . Day two I had a stressful day in hospital ,, it was so hot the heating up on full and still my face stayed calm ,cool and fairly pale . However day three was not good ,, my face felt hot and throbbing , still not as red as normal but other parts of my face not normally effected by flushing started to turn red . It’s now day five and I,ve completely stopped using it . What I thought was the answer to all my dreams is now my worst nitemare . My entire face is bright red and burning all day long . Areas that were never problem areas are now permanently a very dark sinister colour . Please think carefully before using this cream . I,m hoping my face will calm down . I ,m even waking up with a severe flair up that has never happened before . This is not good

    • Sarah Jane Dawson says:

      Does anyone have any experience of the rebound flushing lasting a long time after using Mirvaso cream . I haven’t used it for a few days but my face is red ,, hot ,, blotchy ,,the worst flushing I,ve had with no triggers involved x

    • Kris says:

      Who else has this worked for?

    • Mel says:

      I have the same problem. It is heartbreaking and my skin is worse than when I started using this crap stuff.

      • jenifer says:

        Hello, I wanted to see if you were able to recover from your usage of the Mirvaso cream. I am suffering myself now and wanted to see if there are any results or hope of getting better and I hope you have

  7. I'm sad says:

    I hate my rosecea, It mates me depressed, reclusive I would do anything to have clear skin, suicidal thought, and kills my skills with the lady’s, heard some good reveiw and some bad ones about mivarso going to try it will let you know how I get on.

  8. Mel says:

    First 2 days I was so very happy with results. I looked normal again. Day 3 progressively got worse. My skin is now worse than ever. $90 A TUBE!! Can’t believe I got sucked in. I have now not used the cream for a week and my skin burns constantly and is redder than ever.

  9. Dan says:

    Used the creme for a couple of months with an overall good result. Then began to suffer impetigo after even brief use. I thought I was being careless with it, so I doubled down on washing, clean application, etc., but no use. Now I use it maybe 8x a year, but I have to deal with impetigo breakouts for 2 weeks afterward. Anyone have any suggestions? Thanks.

  10. David Strackbein says:

    I used Mirvaso for 3 weeks and had great success and all redness is gone and no side effects.

  11. Shelia Butts says:

    I use the Mirvosa each time I am leaving home and although it softens the redness and even seems to fade some of the breakout and scarring, it is short-lived. Within a few hours it wears off and my beacon “Rudolph” is shining again. The only thing I have noticed which may or may not be as a result of the Mirvosa is the little whiteheads under my skin on my cheeks seems to be worse. If it were not for these whiteheads and large, extremely clogged pores in my nose and chin, I would actually have clear skin.

  12. Douglas says:

    If you’ve had a severe rebound, read this!

    So, I’ve been on Mirvaso for well over a year now. My rebound reactions randomly started getting worse to the point I was waking up every single day with a level 10 redness. Bright, bright, all the way around, red. I started trying a multitude of regimens and nothing seemed to work. Then one day I was browsing on Amazon and found the 2 greatest products I’ve ever purchased: Apple Cider Vinegar and Aztec Secret Indian Healing Clay.

    Based off the Amazon reviews alone, I decided to purchase these 2 with little hopes and high desperation. After 2 weeks, my rebound reactions have COMPLETELY VANISHED!! I went from level 10 red every single day and wanting to shoot myself in the face, down to no rebound reaction of any kind. It started to improve after a few days, and gradually over 2 weeks got better and better to the point it’s completely gone.

    I don’t know exactly makes it workt, but here’s what I’m doing:
    ACV: Drink 2 shots of ACV daily. 1 shot in the morning, and 1 shot at night. The shots are worse than vodka, but as I’m sure you’re on here for the same reason I am, you’ll get over it once you realize the benefits. Chasing with some thick juice really helps.

    Clay mask: I mix ACV with the clay in a zip lock bag and use it for 3-4 days and make some more. I put the mask on every morning with my fingertips. Simply stick your hand in the bag and smear on your face. Wait 10-12 mins and jump in the shower (drop a deuce while you wait). After you get out, you have about a 60 minute window of normal and regular skin like you’ve never seen before. After 60 mins, your skin is still great and you already passed the “settle down” period. I still use mirvaso and my skin is completely red free 24/7!! Though, I didn’t stop there. After I jump out of the shower, I mixed my daily face moisturizer with ACV and tossed it on my face. As a cleanup toner and to kill off the shine, I used OC 8 matte finish. In all my years of hating my skin and redness, I have never been to the point of complete freedom and confidence that I am now. Truly a blessing. I really hope this review can help someone. These products are all natural and cheaper than any other “rosacea” product other there.

    One other thing to note.. I have the worst combo and acne prone skin ever.. along with some eczema. Well my friends, after 2 weeks, all that crap cleared up too. All my close friends and girlfriend have asked me what the hell I did haha. I put my eczema cream, and acne spot treatment in storage. Don’t need them!

    Links (total $12 for both!):
    Clay: http://www.amazon.com/gp/product/B0014P8L9W/ref=oh_aui_detailpage_o03_s01?ie=UTF8&psc=1
    ACV: http://www.amazon.com/gp/product/B001I7MVG0/ref=oh_aui_detailpage_o01_s00?ie=UTF8&psc=1

    • Douglas says:

      Forgot to add, if you get red mid-day.. add ACV to your daily moisturizer, put it on, and finished with OC 8 matte finish. Your skin will return to normal awesome skin in about 10 mins. :)

    • Shannon says:

      I am actually a firm believer in clay, but I tried this during a flushing rebound outbreak and it made it worse.

    • Bresh says:

      Hi Doug. I am going to give this a shot and was wondering if you could provide some specifics. First, what kind of moisturizer do you use? Second, what ratio ACV/Moisturizer do you mix? Please let me know and thanks for the advice!

      • Douglas says:

        Bresh – So, face moisturizers and my face typically don’t get along. I’ve tried so, so many. With or without spf. Light and heavy. All of it. Some work quite well for a week or two, but then my face starts to crack again. I’ve narrowed it down to 2 that work consistently: (1) Hempz lotion, and (2) Cetaphil Daily Facial spf 50. The first one, Hempz, isn’t a face moisturizer and could cause you to break out. However, it’s literally the only lotion I’ve tried that keeps my skin springy and glowing all day. My saving grace is the daily ACV + Clay mask that keeps me from breaking out. My assumption is that is does such a great job of unclogging pores that it’s not an issue. I’ll touch more on that in a second.

        I also use Paula’s choice 2% BHA lotion prior to applying the moisturizers. It’s an easy application and dries quickly. Seems to eliminate the random redness on my cheeks.

        For ACV + Clay mask, I mix equal parts in a plastic bag. It’s important to avoid using any metal.. apparently it’ll render the effectiveness of the mask. So I just dump in the clay, and pour the ACV on top. It’ll be a little runny at first, but the next day it’ll be thick enough where it doesn’t drip or leak all over the place. I mix for about 7 days worth before creating another bag. I’ve noticed the Mirvaso is much more effective after this mask too.

        Here is my complete regimen:
        1. Wake up and apply mask. Allow 10 minutes to dry. I usually prepare breakfast, get my clothes picked out, etc.. to kill the time.
        2. Shower. I don’t use any face wash because the mask already does an amazing job of pulling out the dirt without drying out your skin.
        3. Apply Mirvaso to appropriate area.
        4. Apply BHA to the rest of my face (where I didn’t apply Mirvaso). I want to let the med absorb without any other ingredients. I’ve had much less success when combined with moisturizers as someone else suggested.
        5. After 15 mins, apply BHA over Mirvaso spot. Apply Hempz lotion over entire face.
        6. Apply OC8 to kill off any shine or grease.

        If I’m going out in the sun for the day, I’ll swap out the Hempz for the Cetaphil and only use a little bit. It leaves a bit of a white hue, but if you use a conserved amount, it actually blends with the red and creates a natural color.

        I did a little test this week/end too and wondered how my skin would react without Mirvaso after 1+ year. Well, I didn’t have any bad reactions after 5 days.. and my rosacea returned to how it was prior to this regimen. Though, I still had super clear skin and my pores are so small these days you can’t even notice them! The mask is truly a blessing.

        I’ve also been experimenting with Hemp Oil (assuming that is the crux of the Hempz lotion), but it’s just too damn oily and isn’t practical for a daily regimen. So, I continue to use Hempz.

        Hope this helps.

  13. Stephanie says:

    I just started using Mirvaso and so far it has worked great. I only put it on my nose…I never knew I had freckles on my nose. Hoping it continues to work well.

  14. Will says:

    Okay.. so I haven’t yet tried Mirvaso myself but after reading these comments I have to put my opinion out there. I’m a medical student, not a doctor (yet, or dermatologist), but from what I know it seems like a lot of these bad/rebound effects users are experiencing may be due to misapplication of the cream and not avoiding normal triggers:

    1) If you are using enough to make your face completely pale, you are using too much! Dilute with a lotion or use much less Mirvaso… The point of any medication should be to improve your symptoms, not treat them so aggressively that you go past an acceptable improvement. So… I would start slow and increase the amount applied each day until my redness is reduced to an amount I was happy with/ felt acceptable. Even if this means that slight redness is still somewhat present. Applying a TON of cream and getting pale should not the goal and it is not the purpose of this drug… Doing this will produce rebound flushing like so many other vasoconstrictors when used in excess….

    2) If the medication is supposed to be applied only once per day.. follow the instructions!!! Yes, that might mean that if you want to reduce redness at night for a party, you won’t be able to use it that morning for when you go to work. But that is a tradeoff you need to make. Many vasocontrictors on the market today, for other diseases, also have a limit to how often you can take them because overuse (even in the smaller amounts that I described above) can ultimately lead to rebound.

    2) I keep seeing posts describing how “the first time I used Mirvaso, not even red wine or sun (or whatever my old triggers were) caused me to flush!!!” And then they wake up the next day with horrible “rebound” flushing… In my opinion this is not rebound flushing at all. This is what happens when you spend a day ignoring what you know about your rosacea and start experimenting with all of your triggers.. I myself know that red wine or alcohol or spicy food late at night will absolutely give me a bad complexion the next day! Remember, Mirvaso is not preventing the release of histamines (inflammatory signals) in your body that normally cause redness.. those things are still released. All Mirvaso does is temporarily prevents your blood vessels from dilating in response to the inflammatory signals. So… when the medication wears off the next day you can bet that your face will not be happy. So AVOID TRIGGERS even when using Mirvaso!!!! Even if you think that your lack of symptoms in moment must mean you’re invincible to them, because you’re not!

    I’m sure many of you have followed these pieces of advice already.. but for those of you who haven’t it might improve the success rate of this cream.

    • Ann says:

      Excellent points! My dermatologist told me to use a pea size amount for the whole face, rather than a pea size amount for each area (Mirvaso instructions). While following that advise I have never had an issue with Mirvaso. Once I decided to follow the med instructions and that definitely was not a good idea! The only time I have flare-ups or “rebound redness” now is when I eat or do something that I know is a trigger. We all want a miracle that will allow us to do whatever we want without repercussions, but that is not realistic.

  15. Joan says:

    My derm gave me some small sample tubes only saying to use it on the red areas and that it would definitely work. I tried it out before going to an evening symphony performance. Didn’t use much but was shocked to see perhaps a half hour later that I had gone completely white where I had applied it–but I looked ridiculous because the parts I hadn’t touched looked super red in comparison. So I had to cover those spots too with a thin layer and in about 45 min. I was completely white.

    While I found it fascinating to see how pure white I could look so quickly I honestly thought I looked rather sickly. Also, more disturbing was that the entire evening I felt like my face was deeply flushed even though there was no evidence of it. I kept asking my companions if my face was flushed because it felt so hot–but it didn’t look it at all.

    I think Mirvaso is interesting but I don’t see how it can be called a medication. It seems to be like a temporary eraser for the redness, but just like Cinderella, you’re going to go back to your former state in a few hours. My cosmetics can do a better job without the unpleasant sensation and the deathly whiteness.

    • Jo says:

      The previous points from WIll are EXCELLENT! I too have been experimenting with different amounts of Mirvaso and agree with Will that one should use the minimal amount of any medication to treat symptoms. By doing this, I have been using Mirvaso successfully for over a year now.

      With regard to Joan above, Mirvaso IS a medication used to treat redness and flushing just like say, hypertensive medications. If you stop a hypertensive medication, your blood pressure will return to its elevated level the next day. Their effects are “temporary” as well, yet millions of people continue to take them daily.

      Joan, try using a lot less Mirvaso or weaker concentration to avoid over-whitening. Good luck and Happy Holidays!

    • claudia says:

      i find it interesting that many ppl report feeling flushed but there is no flush.

      i think this medication by simply inableing the flush on the skin may drive it deeper. this could lead to a bild up of a very excessiv vascularsystem deeper in the skin wich might break through later in life(weeks, month, years). could be really dangerous!
      so even ppl who tolerate this substance well at first could end up hurt.

      and that most ppl seem to flush in the late afternoon, early evening is simple, because at that time the body has the highest temperature through out the day.

      (sorry for bad english)

  16. Shannon says:

    I received a few small samples of Mirvosa from my dermatologist. I have mild rosy cheeky with no other symptoms. On day three of applying once a day my entire face below my eyes on both sides turned bright red. Even on places I didn’t apply the medicine. My redness was just on the apples of my cheeks and now I am flushing with the entire cheek being red. It is hot to the touch, which has never happened before. I am freaking out! Someone please tell me this is not permanent. I am on day 2 of the rebounding redness. How can dermatologist be so carless? I trusted her, I never thought something like this would happen from a topical gel. I wish I would have researched this before putting on my face. I never would have thought a topical gel could do this much damage. Please, someone assure me this will go away!!!

  17. shannon says:

    There is no way it will ever touch my skin again after that reaction! I am just hoping it’s not permanent. Yesterday I woke up without the burning red flushing it caused but it came around 4. Praying it doesn’t come today. It looks like my face is on fire, everywhere on my cheek. Dangerous stuff!!!!!

    • Sandra kramer says:

      I had the same painful reaction. I agree it is dangerous stuff and potential users should be warned. I was not; instead my derm did a biopsy when I had a severe reaction. Left a scar; I will give him a very negative review. He will look elsewhere for his business.

    • shannon says:

      Why would someone chance putting ANY amount of this stuff on again? It’s been almost 2 weeks and the redness has gone down a title but I am still flushing in places I had NEVER flushed before. Still waiting to see if my baseline was made worse PERMANENTLY. I don’t think you understand how dangerous this medicine is, for A LOT of people.

    • Kevin says:

      I tried what Kari said. I was skeptical, but it really does work. Thanks Kari!!

      • Shannon says:

        No thank you, It’s been a month since I put it on my face and I am still having rebound flushing. Last night my face started getting hot and bright red. My face NEVER did that before using this DANGEROUS medicine. Still praying these reactions will go away one day.

  18. Lynn says:

    I was so excited, it seemed like a miracle! It was great for 4-5 days, incredibly great!

    But a few days later (4 or 5 I can not recall), I blushed due to an uncomfortable situation at work and the redness and heat exploded from my face and did not reduce for more than an hour. I actually had a sample in my pocket and applied again (I know not the best idea but I was very embarrassed and would have found a closet to hide in instead). Since then, I found that I hate this product. Thank you all for sharing your stories, I only wish I would have seen/read this before.

    I also hope that this redness doesn’t last permanently. Very very unfortunate

    • Robert says:

      Not trying to sound negative but I used mirvaso 7 months ago and the redness is still in full force. Hopefully your skin heals better than mine. Good luck.

      • padwenda says:

        Hi Robert, I used Mirvaso only twice and I too have permanent redness and the flushing is unbearable! It is now over 11 weeks since I last applied it and it has not calmed down. I only had a mild case now I have red burning skin that flushes easily and now I’m getting spots! I believe this is permanent and I will never get back to my pre mirvaso state.
        Did you report this to Galderma? I have found Galderma so unhelpful and they claim everyone gets back to “normal” after a few days!

    • Sandra says:

      You are so right Shannon. I will never let it touch my skin again. It is indeed dangerous and the FDA needs to be kicked for not stopping it.

  19. m says:

    If your a flusher, this medication won’t work for you…let me know if there is a proven anti flushing medication..

    • Julie says:


      I’m a flusher and the cream worked for me no flushes during the period when the gel is working. The problem for me is when the drug wear off and the next day if I don’t reapply, hope you find something that helps. Julie

  20. Will says:

    Thank you to everyone who warned be about the potential side effects of Mirvaso. I’ve been using it now for about a month somewhat successfully, but have been VERY careful because of what I’ve read here. So far I have been only using it at most every other day, and I only use about one pea-sized drop mixed in with my face lotion. I am also careful to only apply the medication on areas that get red to avoid developing redness in areas that weren’t red before. So far I haven’t had any problems with rebound, but my baseline redness also does not completely go away after I apply Mirvaso. I’d say the redness improves maybe 40-50%, enough so that a tinted sunscreen can help make my face look normal. But even then my cheeks still look slightly red. So I guess for me Mirvaso is just another tool in the toolbox to help mask redness but it does not work completely by any means.

    • diane says:

      Yea!!!!!! So uplifting to hear some good news on M. So happy for you!!!! Diane

      • m says:

        I have been following this thread for a couple of weeks with no responses. As soon as I post what is perceived to be a negative comment about Mirvaso, someone has to respond with “mix a small amount with moisturizer”. If this works so well, why isn’t this thread filled with success stories? Trust me. As a rosacea sufferer I wish it would work. But it doesn’t. Tried it.

    • Kari says:

      Awesome to hear that its working for you! Truly a blessing.

  21. A says:

    So after seeing those types of articles claiming the rebound flushing is rare, I thought it was fine to try it. I mean what were the odds?

    I applied it 4 times, I didn’t do it ‘every day’ as instructed, I thought maybe it’d be safer to use it less often. Maybe if you apply it constantly it is reapplied before the rebound flushing.
    If you think the ‘rebound flushing’ is just the return of your normal worst redness, it isn’t. Every part you applied it to will flare up far, far worse than was your worst normally, even parts that never did before, and this doesn’t go away again.

    Time 1: Applied it to one cheek. Worked great. Next day when it wore off that cheek is wayy way redder than before. But I thought maybe it was coincidence, maybe I just forgot how terrible it was or something.
    Time 2: about a week later, applied it to that cheek again. Like before, flares up horribly after it wears off. But I thought maybe my rosacea is just getting worse. It’s worse from then on.
    Time 3: about a week after that. Stupidly applied it to both cheeks.
    Sure enough when it wears off now both of them are that hideous bright red and burning up far far worse than it ever was before I applied the stuff. I never had a serious problem with flushing before, especially not on that cheek.
    Time 4: Like an idiot, the next day I am so desperate to stop my face being on fire I apply it again. It’s a few hours later, after it’s already soaked in, that I think maybe the fact the Rosacea has gotten FAR FAR worse the last few weeks, that it’s the Mirvaso stuff. So only now do I search on the Internet and see all the horror stories.

    Well it’s confirmed. The next day the entire of both cheeks (including the sides and underside of my face, which usually aren’t affected) and also my nose are far, far worse flushed than they ever have been before, in places that have never been red before. (And I didn’t even apply it to my nose).
    It’s the day after and no better. There’s all these little red marks that weren’t there a week ago, (I know they weren’t because my face was pale when I applied the Mirvaso the first 2 times) so it’s damaging the blood vessels. So just applying that stupid ‘treatment’ a few times has made the condition far far worse than it ever was before, perhaps permanently. My entire face looks (and feels) like I’m severely, severely burnt or something. It’s not ‘blushing’ or ‘overheating’ it’s looking like there’s something hideously wrong with you.

    In short I do NOT recommend this product at all. If you really, really must try it, apply it to a smallish patch of skin and only that for many days/weeks, allowing enough time between applications to see if it ‘rebounds’ (I advise this trial be applying the gel every SECOND day, so there’s enough time to see if a rebound kicks in.) At least then you won’t ruin your whole face. Only now am I reading all the horror stories about how this ‘rebound’ far far worse than you ever were previously happens for many weeks, months or even never leaves. I don’t understand how this got through the clinical trials. The rebound is a well known side effect when the drug is used for the nose problems. I assume that the people in the trial just applied it constantly before the rebound happened, and it maybe happens if they ever stop. In the ‘real world’ people aren’t going to reapply the stuff on a strict schedule like that, so even if you use it ‘every day’ I bet the rebound can slip through. If only I’d never used it! The things I’d give to take back even one application of that stuff!

    And from what I’m reading, if this nightmare 24/7 face fire is only for a few weeks, I’m one of the lucky ones. I can’t sleep, I can’t go out anywhere, and my previous level of rosacea (which in terms of redness was just looking a bit pink) is merely a fond memory. It’s really scaring me because I don’t know how long it’s going to take to recover, if ever.

  22. brandish says:

    I used Mirvaso for about a week. I have never had an issue with flushing, just redness that seemed constant – but never a deep red, never a hot face.
    My face has been flushing so badly for three days straight now (since I stopped using it – I started flushing in between treatments) that the skin looks swollen. I look like I am wearing a red mask. If this really truly is how my face is going to look for months, then I am devastated. One cheek – or the other- for no reason will flare a violent red. As the day wears on, the rest of my face joins the party. I’ve never had a red chin or forehead, but I look like a lobster. VENDETTA MIRVASO VENDETTA. I feel so tricked and just – simply devastated.

    For people who have managed to find a balance that doesn’t worsen their skin, good on you. I don’t see how it’s possible for me. Even if I wanted to try a different regimen than the actual company prescribes (wait – what? I’m supposed to know the prescription is going to be ruinous to my face and use substantially less?), I should still be able to stop using it and go back to the way I looked before. But that seems also impossible. I’m really sad to read all these posts wish everyone the best.

  23. Joan says:

    Stopped using after the 3rd try. The rebound redness the worse I have seen it in years.

  24. share says:

    Mirvaso is nothing but a topical vasoconstrictor. I’m not surprised that the skin is red days after a treatment. The vessels are probably working overtime to make up for 8 hours of constriction.

    This stuff did not work for me. I have tubes of unused samples, and an untouched prescription; never filled, not even once.

    Of the 3 or 4 times I used it, mirvaso barely made a dent in the rosacea redness in my cheeks and left my whole face (flaming) red for days after.

    Not worth it.

  25. Alexandra says:

    I have very mild Rosacea, with occasional mild flushes on my cheeks. I started using Mirvaso 5 days ago, and during the first two days I liked how it made my skin pale and that it lasted for entire day. However after it wore off, my skin would be much redder than it usually was, with some occasional really bright red spots in unexpected places on my face skin. Starting from the 3rd day of usage, my skin started reacting really bad just after a few hours of using the product. I would have an extreme flushing (that also burns) for an hour, and then it goes away, but then in the evening I would have a maroon color of my face. I stopped using the product on my 6th day, but I still got this extreme flushing in the middle of the day. This product didn’t work for me. Moreover, it made my condition 10 times worse.

    • caressa03 says:

      I’m convinced that a good gentle make-up which is long-lasting, waterproof, or not & a sunscreen before that for a baby’s or sensitive skin, that agrees with one’s facial skin will be more beneficial for the complexion & cheaper than this ploy by a pharmaceutical company to pull the wool over one’s eyes, & to yes, to try to avoid your rosacea triggers …And, to stay clear of this, & the Benadryl cream to avoid a reaction to being able to even use this RX…This, for me, seems Ludacris..

      • Victor says:

        My dermatologist advised me to proceed slowly with this gel, adding a small amount more per day to my regular rosacea moisturizer. Even a small amount immediately cleared up my redness for almost the whole day. I have been very happy with it. For anyone having problems, try this “go slow” method that my doctor told me about.

  26. JS says:

    Works well for about 6 hours and then comes the intense rebound which makes me red on the neck where I have never had redness. I went to another dermatologist for a second opinion and she said that this was so common that she stopped prescribing it. For $50 per tube (Insurance covers over $150 with the rebate), I am NOT impressed at all! I will not be using this again. I think the company should give refunds. I hope this rebound redness goes away! It makes rosacea worse than ever.

  27. Chloe says:

    I started using this 2 days ago and was initially impressed by the reduced redness on my chin in particular. It went on smoothly and felt fine. Now, I am experiencing rebound flushing worse than ever that stings and burns. My cheeks are SO red and sore and I fear after reading some reviews that this rebound won’t go down…I will not be using this anytime soon again as I’m in a position now of pain and horrible flushing that was nowhere near as painful before I started using this.

    • Doug says:

      Hi All,
      I left a reply a month or so ago with instructions on how to use Apple Cider Vinegar and Bentonite Clay. I continue to use these products and they’ve SIGNIFICANTLY reduced my rosacea problems. I would highly recommend this regimen if you’re having rebound or flushing issues. Best of luck to everyone and please reply back if it works for you so others can share in its goodness.

  28. Kelley says:

    I’ve been using Mirvaso for a year. I do experience some flushing around 4-5 hours after application that goes away after about 30 minutes but other than that, my face is free from redness for 12-14 hours after application. I try to skip using it on sat and/or sun if I’m not leaving the house, due to the fact that the rx is pricey, and on those days my face does get super red but that only lasts for a few hours.

    With that said, I saw a new derm yesterday and she wants me to try some other prescriptions and only use the Mirvaso like a “rescue med,” if my face is really red and the other meds aren’t working. She says that with some people, your body can get used to the cream and stop working altogether.

  29. Julie says:

    The drug work really well, amazingly well for 9/10 hours, the problem starts when the drug wears off. The redness returns fast but in different parts of the face at different times! So I could have a bright red nose but cheeks will still be white! If I don’t use the cream the following day I will get some odd bight red patches in places this is more than 24 hours after application. The redness is fiery and hot. It’s not fair! It really works but its not worth dealing with the next day!

    • joeyr says:

      Try cutting back by mixing a very small amount of it with an antihistamine cream or moisturizer. You will be less red after it wears off. My derm recommended this for me.

      • Julie says:

        Thank you for your tip it’s much appreciated. Did he explain why you get the reaction? I will try and see if it helps. Would be a shame not to beable to use the drug as it’s great!

  30. Pat says:

    Differen helps clear clogged pores. I have a “Rudolph” too:) Its 9pm and I just put on Mirvosa for the first time and it seems to have taken the ruddy look away but not the red-spider veins. I hope I don’t experience the burning that some people have because I really want to sleep tonight and wake up to a no Rudolph nose:) but honestly I am happy with the red reduction in my complexion right now.

  31. Dan says:

    I have used it for a week now and it works great for me. It starts working almost right away and lasts for 6-12 hours. I only use it when I have to, i.e. when I am at work and don’t want to be embarrassed by my red face. It is expensive so i use it sparingly.

  32. Samantha says:

    I got the prescription and and used it the first day and it did work for the redness but that night I did get the rebound redness that was much much worse than my ‘normal’ redness, my whole face was red whereas before just my cheeks and nose were. Well I figured as long as it worked during the day when I was at work or out I could deal with the rebound in the comfort of my home.. Well 3 days later the redness was worse, a lot worse. My face was RED and this was 3 hours after applying which hadn’t happened the previous days. I immediately stopped using it and figured I would rather have my normal redness than what I saw in the mirror. The next day my face was very red welted up, my lips, nose and eyes were swollen! I went to urgent care because it was a Saturday and my doctor was not available, they say I had an
    adverse reaction to the Mirvaso and should stop using it immediately (which I already had)
    and they had to give me steroids to reverse the reaction. I wish I had never used that medication and hurt my skin like that, it was terrible, hot to the touch and itchy, not to mention
    how bad it looked. If you are thinking about starting this medication please make sure you read about it and understand it does come with some side effects, I should have read more reviews about it before I tried it, ending up in urgent care,

  33. John gilligan says:

    My only advise is not to use. When I first started to use, it really cleared my rosacea and I was delighted with the results. However they were short lived!!!! After about 6 weeks I got a rebound reaction where my skin was redder, sore and tighter than ever before and it’s taken a week of not using for my skin to return to some kind of normality. I’ve been using Aveeno Ultra claming the last few days and my skin is a lot better, with minimal redness .I will certainly never use Mirvaso again and will in future check reviews online before trying a new product. Please make sure you read about it and understand the risk of side effects.

    • diane says:

      Your very INTELLIGENT, WELL WORDED advice is truly exceptional. I can tell you are
      an intelligent, knowledgeable, perhaps even well educated individual unlike some of
      the responses that are barely intelligible and are of no use as far as anything to
      emulate re treatment, pros and cons, etc. Best of luck. Diane

  34. Jakub says:

    For me it works but not in 100%. Ive been experimenting with Mirvaso for 3-4 months. I use it everyday before school. My redness is pretty bad and I have got P&P too.

    Mirvaso reduces redness but not completely. I can say that reduction is from 60 to 70%. There are some days when i dont have redness at all (while using Mirvaso ofcourse) but for the rest of them its visable.

    I have had rebound couple of times. I can say only about myself but Im using less amount of cream than what’s reccomended by my doctor/mirvaso website.

    I have got redness on my cheeks forehead and nose( its the worse there, all the time red and looks pretty bad). My Nose is very oily so i only use Mirvaso on it while on the rest of my face I use Mirvaso firstly and than after 10-15min I apply Bioderma sensibio AR BB Cream. Its SPF +30 with little makeup.

    Mirvaso does not work for my Flushing. If the weather is too cold or too hot my face gets red. When Im nervous or embarassed it also doesn’t work.

    I think that my face now is addicted to mirvaso. Last weekend i didnt use it and i was so freaking red that it made me laugh :D. I looked like red tomato santa claus :P. It was rebound for sure but I have also drunk a lot of whisky with my friends and alcohol is big trigger for me.

    Mirvaso is pretty good product it works for me but it’s not a cure. Im going to try IPL lasers next year when it will be cold. I’ve done it 3 times but i saw no effect( I think i’ve chosen wrong person to perform it because it was cosmetician. Treatment was painless while I have read that it should be painful and I should have bruises).

    I also hope that soolantra will be available soon because it may help with my P&P and maybe redness :D. My rosacea is genetic my mother has very very mild form of it and my grandfather had same as me( but he was old when it affected him when I am 20 years old 😛 )

    Also one more note. I feel really sorry for you that u have to pay such big amounts of money for this medicine. In Poland it’s pretty expensive for our money earnings but holy crap in US without insurance it’s hardcore. Mirvaso costs here something like 60$. You may say that it is not a money, but it is here 😀

    If you have any questions feel free to asks. I’ll answer if Im able too :)

    PS. Sorry for grammar and mistakes

  35. Kary says:

    I’ve recently started treatment for my pretty mild rosacea. My dermatologist has me applying Mirvaso in the morning and Soolantra at night. I started this 5 days ago and was pretty happy with the results. Last night, about 30 minutes after washing my face and applying Soolantra, my whole face got very red and hot. It looked and felt like a bad sunburn. I assumed that it was the Soolantra, which I had just applied. Called my dermatologist this morning, and he suggested staying off the Soolantra for a week or so, and only applying Mirvaso in the mornings. All day today, my face has felt hot, even though it hasn’t been much redder than usual. This evening, my face is just as red and hot as last night – even my lips feel hot. I’m thinking the Mirvaso is probably to blame and not the Soolantra. Anyone else trying both at once? And what would you suggest?

  36. Tammy says:

    I had really bad rebound. Not was my face on fire it had welts.

  37. Sarah Davies says:

    Hi everyone.

    I was so excited when I first heard about Mirvaso. I got the prescription from my Doctors a couple of weeks ago and then ordered the Mirvaso at my Pharmacist. It was on NHS so quite cheap at £8. I applied straight away and noticed a difference within half an hour. It did seem to make my broken veins slightly more apparent but my general redness was massively decreased without the “ghost like” appearance some of the reviewers have commented on. I only used a tiny pea sized amount each day and for the first 4 days or so thought it was great.

    Then came the rebound flushing… About day 5 or so, the redness started to appear only a few hours after applying. A couple of times I was going out, so I did apply a tiny bit more. I’ve now gone about 3 days without using it and find that in the afternoon, I’m bright red. The worst I’ve been for years. So depressing. My doctor asked me to let her know how it went and I will definitely be giving it a No, please don’t prescribe for other patients.

    There seem to be so few positive comments on here but maybe the people who it helps don’t post?

    I find using Dermalex Rosasea cream does help soothe and calm down the burning feeling in my cheeks but I just wish I’d never used Mirvaso in the first place.I might actually contact the newspaper that had the review that originally prompted me to try it. They should know the true picture of the rebound flushing. I also feel that I’m losing the sensation in my cheeks? Has anyone else experienced this?

    I’ve ordered the Clay, ACV and Hempz that another reviewer recommended and will see how I get on with those.


  38. Joeyr says:

    I know that everyone on here likes to whine about their problems, but here is an interesting post about Mirvaso from a dermatologist on the site Realself:

    “Rosacea is characterized by increased blood vessels too close to the top of the skin, usually due to chronic sun exposure in people who have more of a tendency for inflammation. When the vessels are too superficial, there is too much activity in the surface of the skin, leading to flushing, blushing and sweating. Mirvaso is a vaso-constrictor, making the superficial blood vessels close. Some people report a rebound effect when they stop using it, but I’ve found that most people do not experience this effect. The best treatment is to close down the blood vessels with the PhotoFacial procedure. Another possibility for patients who have a significant amount of blushing and flushing is to use low dose clonidine, a blood pressure medication. It acts in the brain to decrease the flushing and blushing. I would suggest trying Mirvaso and see if it works for you. In the long run however, it may be more cost effective to simply close the vessels down with the PhotoFacial procedure.”

    • Mark says:

      Well I tried it and it left me with a red raw burning face that took over a month for it to calm down. Mirvaso is terrible, I for one will never use this product again.

  39. m says:

    Enough said about the damage and pain caused by Mirvaso. I hope a REAL solution comes soon…

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