Mirvaso User Reviews


Mirvaso is so new that only a few rosacea sufferers have been able to try it.

What are your chances of having a bad reaction ?

How are users in the real world faring, and will the general population see the same level of benefits as the large number of Phase III trialists ? So far it seems that many more people are having bad rebound reactions to Mirvaso, compared to the clinical trials.

Well one way that we might get an idea of how Mirvaso is being received is if we can collect reports from people who suffer from redness and try it and give us all some feedback.

Please do leave a comment if you have tried it and have an opinion.

How Well Does Mirvaso Work?

Well your response to Mirvaso is likely to fall into 1 of 4 camps;

  1. For starters, there is going to be a group of rosacea sufferers who won’t be able to use Mirvaso at all because of another condition that is incompatible with Brimonidine.
  2. Some users will get a flush reaction that will probably mean that they will stop using Mirvaso.
  3. Next, there will be a group of rosacea sufferers who get a mild to moderate reaction but will choose to continue to use Mirvaso.
  4. Finally, and hopefully in the majority, will be a group of Mirvaso users who see a good relief in their red face.

Mirvaso Reviews

Alan says:

 Not as impressed as I hoped to be, but only on my 4th day.

dogkrazy says:

I haven’t seen any rebound, but it does wear off. I use it once a day after my shower.

At first, it gets a bit redder looking but a couple hours later it blanches out..rather like pushing your finger hard on something until the pink turns white…it looks tons better!! the less red side almost looks normal on it.

alfypet says:

I tried my Mirvaso today for the first time. I applied about 45 minutes ago. The good news is that I have not reacted badly thus far. I am so used to applying a topical and immediately getting red and flushy, so that is a big plus for me.

The area on which I applied the cream has definitely paled. Surprisingly, this does not necessarily make me look better.

and then;

The good news is that I have used it for three days now and have seen no ill effects. That is huge for me, as I usually react to everything! I can’t use Metrogel, Finacea, Promiseb, Xylogel, etc, without reacting with redness or flushing.

The Mirvaso definitely helps with diffuse redness, and I think a lot of people will have great results. Under my redness, I have visible vessels, which I was hoping would not be visible with Mirvaso. But for me, they are still visible, and no longer hidden by the redness of my overall rosacea. Honestly, had I never had laser treatment and Veinwave, which made these veins more visible, I think I’d have much better results.

I do feel, however, that applying Mirvaso takes down my rosacea, in general, a degree or two. My face feels calmer and less reactive so far. I am at work today, which will be a good test. I usually flush on a daily basis at work at around 6/7 pm. I’m not sure why, but it is probably anxiety trying to finish my deadlines and get out of the office. I’ll see if that happens today.

anon24 says:

Okay I finally picked up Mirvaso from the pharmacy. Using the savings card, I only had to pay $50 for the 30mg tube, and I don’t have a great insurance, so most folks will probably get a pretty good deal on it. I applied it in the parking lot in one spot, ran some errands, and came home, and its now been about 40 minutes. I did about a quarter sized area, and the redness has subsided a bit, but nothing to write home about. I don’t know if it starts to work more after 30 minutes, I assumed that at 30 minutes it was working at maximum ability, but I will post more updates later. It is very easy to apply, spreads very easily (it’s a clear cream, kind of like vaseline), and doesn’t feel drying or anything like that. So the redness is reduced after about 40 minutes, not nearly as much as I’d hoped, but I will update later.

Steven says:

So I got it – about a week ago – used it 4 days – looked great at first, then seemed to have some breakthrough redness before the 12 hours were up. Thought I would stop using it for a few days as I thought I might be developing tolerance to it. The day after I discontinued it my face has been flushed more than before I used it. So rebound redness seems to be potential problem – It certainly has been for me.

wiry says:

Early Review: I tried it on the entire face. I took about 45min-1hr to kick in.

– The forehead results seem to be pretty decent.
– Cheeks were blotchy. Some spots were too pale, which increased contrast from the redder areas.

I think my cheeks looks worse with Mirvaso because it was just too blotchy. Some areas are too pale and unnatural looking. Have you ever heard someone say you look like you’ve seen a ghost? Well, it sort of looks like that. The forehead seemed to give a better cosmetic result. Perhaps with some experimentation one could get it look better. I will try some different approaches and see what happens.

Overall, I think with enough experimentation (and fingers crossed there is no rebound flushing), this could be a useful medication. But I think it will be tricky to really good natural looking results (at least for me). Its a little “black and white” or should I say “red and white”. Maybe if I were to dilute it a little and just go for a toning down of redness, it would be better.

littlelassie says:

This is my third day using Mirvaso and my first day to apply it in the morning instead of the afternoon. Today isn’t the greatest test because I also used little makeup since I was going to be with other people all morning and am a chicken. Interestingly enough I haven’t seen the same degree of effectiveness the past two days, but I believe that’s either because I am using less than the first time or because I have started mixing it with Cerave lotion to help it spread more easily. That being said, my redness has mostly disappeared by 45 minutes after application, I just don’t look freakishly pale. The one thing that bothers me is that at around 5-6 hours I start to see some pink/red coming back. All three days the redness first appears in my t-zone. I think it might have something to do with my skin becoming oily?

Matt_Seattle says:

Test Patch Review:

Well Mirvaso definitely works (at least it did for me). I first applied it just to a section on my nose and it turned it completely pale in that area (took about 20 minutes for the effect). There was no stinging and it applies smoothly (no scent really either) the texture reminds me a bit of cetaphil moisturizer or Cerave PM.. Very thin and easy to absorb. Now after the first application and as others described, it almost looked like an obvious pale spot with surrounding pinkness, but after taking a tiny bit more, working it through the finger tips and lightly applying to the rest of my nose while trying to fade it lightly into my cheeks, it smoothed out and gave a natural pale complexion to my nose. Im pretty impressed with how good it actually works.

Acanthous says:

I used 3 pea-sized blobs for whole face, at 2pm on the day I got the script ($50 w/coupon). I am a flusher, with many, many triggers, including ‘being alive’ and ‘breathing’. Deepest flushing is on nose and cheeks, but rest of face, neck and chest also flush. I always have some redness. Observations:

– I was white like a vampire for approximately 14-15 hrs. Not even red wine and pasta made the treated areas flush.
– this is not as good a look as I imagined it would be. Also, it highlighted the neck and chest flushing I have.
– some normal flushing started coming back on face and cheeks around 8am the next day.
– extreme, weird rebound flushing on cheeks starting by 9 am. Deep, blotchy flush, very hot and uncomfortable.

Renae says:

I have used mirvaso for the past three nights and the results are amazing!!!!!!! The redness/burning/swelling is totally gone! I do look pale in comparison to my normally flush appearance but i couldnt be happier with the results. I’m going to not use it for a few days and see what happens. Has anyone else had the same results as I have?

redman says:

Got it today. Left the Drs office, washed face, applied. 20 minutes later I walk in the house and my wife tells me I look pale. Not pale, I tell her. This is my correct color and that she should try it as well.

Renae says:

I just tried mirvaso and I cannot believe the difference it made with the redness/telangiectasias!!!!! I’ve tried every cream(finacea, metrolotion, oracea etc).

Scotty says:

Hi All – got a sample of Mirvaso yesterday from my Dr.  I used it for the first time this morning after my shower.  Didn’t really think much about it (had little faith to be honest) until I went to the restroom at my office.  Looked in the mirror and was very impressed!  It usually takes a long time for my skin to “settle down” after a shower etc – but my redness was VERY improved!  I still can’t believe the results.  So far I’m a fan.  We’ll see how it goes.  Good luck!

GreenGables says:

Using Mirvaso for 3 weeks. My derm recommended it at my appointment last month. I hadn’t heard of it before. But my derm is fairly on top of new treatments, and she said she’s had positive reports from her other patients since it came out in September.

Maybe that will change the longer I use it, but right now it’s positive for 3 weeks and counting.


I have been using Mirvaso for 3 weeks without any rebound flushing. Of course it all could change at some point, but so far it has worked for me.

Please Leave a Comment

If you have tried Mirvaso, please leave us a comment below so that we can all get to see how well it is going as a treatment – thanks!

Rebound Redness

There is a growing body of reports of bad flushing reactions to Mirvaso. It isn’t yet clear why this is; that it appears that users are having bad reactions to Mirvaso a higher rate than was seen in the Phase 3 long term trials. Take care and work with your doctor if you think you might be worse off after using Mirvaso.

So please do let us know in the comments below whether you stick with Mirvaso or have to stop using it.

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About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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  1. darryl Hutchinson says:

    Was prescribed the new wonderdrug Mirvaso for my Rosacea. I reacted badly to it and got tingling, heat and flushes as bad as any I have ever had. I was on holiday and had a burning face SOLID for about 4 days in the hotel, and took 2 weeks to recover from it. I still have 29 of the 30g still in the tube but won’t go near it. My GP reported my reaction back to the drug company but they reported no such reaction in their trials….makes you wonder though!
    After all the hype of mirvaso I was really disappointed, and it is clear here at the group others had the same findings. Maybe they should have asked us to participate in the trial before getting our hopes up!

  2. Research findings says:

    Long-Term Use of Brimonidine Gel Decreases Levels of Erythema in Patients With Rosacea: Presented at EADV
    October 10th, 2015
    Tags: Conference Dispatch
    By Jenny Powers

    COPENHAGEN, Denmark — October 10, 2015 — Topical brimonidine gel (0.33%) applied once-daily by patients with moderate to severe erythema of rosacea, resulted in decreased erythema levels within 3 months that were sustained over the course of a 12-month study, researchers reported here at the 24th European Academy of Dermatology and Venereology (EADV) Congress.

    Importantly, patients’ self-esteem and confidence also improved as their rosacea symptoms responded to treatment. Following 12 months of gel use, 48.5% of 131 patients who responded at baseline that rosacea inhibited their social life stated they no longer felt this inhibition.

    Of 145 patients who responded at baseline that they avoided public contact because of their rosacea, 59.9% stated they no longer avoided public contact.

    Of 77 patients responding ‘yes’ at baseline whether rosacea made it difficult to establish relationships, 59% responded ‘no’ after 12 months of treatment.

    Gregor Schaefer MD, Galderma SAS, Paris, France, and colleagues conducted an open-label, multicentre study in 27 centres in the United States. Patients with a clinical diagnosis of moderate to severe erythema of rosacea at baseline visit, according to both Clinician’s Erythema Assessment (CEA) and the Patient’s Self-Assessment (PSA) were enrolled. Patients applied a thin film of topical brimonidine gel 0.33% once daily for 12 months. There was no restriction on the use of concomitant medications.

    “Rosacea has a variety of clinical manifestations but the central diagnostic feature is diffuse facial erythema that persists and increases in intensity during a flare,” explained Dr. Schaefer. “Telangiectasia or dilated blood vessels may also be present, as may papules and pustules.”

    Brimonidine is a highly selective alpha2-adrenergic receptor agonist that has a rapid onset of activity that generally peaks at around 3 hours and lasts for 24 hours.

    Erythema was assessed just before the application of the gel, at baseline, week 1, month 1, month 3, month 9, and month 12 using CEA, PSA, and TGA scales. Patients completed questionnaires regarding the impact of rosacea on their social life at baseline and every 3 months.

    The erythema score prior to treatment application was improved within the first 3 months on study and continued until the end of study. After 12 months, 69.6% and 66.0% of patients demonstrated at least a 1 grade improvement in pre-application facial erythema levels compared with the pre-application baseline levels, as assessed by the patient using PSA and investigator using the CEA, respectively.

    Telangiectasia improved rapidly within the first 2 months and improvement was sustained. At 12 months, 44.0% of patients had at least a 1 grade improvement in the pre-application level of telangiectasia compared with baseline.

    “Reduction of pre-application erythema levels may make the skin appear whiter so it could be expected that telangiectasia would be more visible; however, pre-application telangiectasia levels were also improved,” said Dr. Schaefer. “Overall, the results suggest that long-term use of once daily brimonidine gel may have beneficial effects on rosacea patients beyond daily erythema.

  3. Deb says:

    I am also having rebound flushing after using a sample from my dermatologist. Very hot and uncomfortable. I only applied the cream 3 times. I should have left well enough alone because I was having good luck keeping flushing at bay after discovering I had some food sensitivities (not allergies) to unusual things: bakers yeast, rice and eggplant. One of the best things I ever did for my rosacea was getting tested for sensitivities!

  4. Eamonn says:

    Disaster for me.Used Mirvaso for one month and had to stop as I got extremely bad rebound flushing which made my face and neck like a tomatoe.Since I stopped using Mirvaso and Rozex gels, my colour is now normal pale.I noe use beta blockers which helps greatly.

    • Lisa richards says:

      Rebound from Mirvaso is horrible.
      I look like a clown with a beet red face.
      I am horrified.
      How long will it take for this mess to go away?
      The drug company lied about the effects of this drug

  5. Tim says:

    Onrealtea/ Mirvaso did not work for me here in Canada. MY GP gave me free samples of the drug to help with Rosacea— something I hadn’t been diagnosed with though I battled acne for 2 decades. First application: great. Much of my skin appearing light and blemish free for a few hours. Later I noticed the burning, the itching, the shortness of breath. Never imagined it was due to a few drops of creme and tried it again the next day. Same reaction. 24 hours of wanting to scratch my burning, swelling face as well as shortness of breath. All very scary. My face is a mess. Be careful with this ‘cure’ all.

  6. marshal says:

    ive been using mirvaso now for 5 months no flare ups seems to work fine, but doesnt take redness away from my beak, i get it free on nhs scotland
    i put it on after i wash with a liz earle cloth and plain scottish tap water hot as i can handle.

    i dont know whether rubbing it in is any better than just smearing it on,
    im 48 and have the permanent redness now, but no flaking or oily skin,

    i have noticed that i still look terrible under some indoor lighting, although looking in mirror i look fine

    im very worried about my rosacea, and how people look at me and think im a heavy drinker.

    im severly scunnered with this disease

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