Mirvaso User Reviews

Mirvaso Tube

Mirvaso is so new that only a few rosacea sufferers have been able to try it.

What are your chances of having a bad reaction ?

How are users in the real world faring, and will the general population see the same level of benefits as the large number of Phase III trialists ? So far it seems that many more people are having bad rebound reactions to Mirvaso, compared to the clinical trials.

Well one way that we might get an idea of how Mirvaso is being received is if we can collect reports from people who suffer from redness and try it and give us all some feedback.

Please do leave a comment if you have tried it and have an opinion.

How Well Does Mirvaso Work?

Well your response to Mirvaso is likely to fall into 1 of 4 camps;

  1. For starters, there is going to be a group of rosacea sufferers who won’t be able to use Mirvaso at all because of another condition that is incompatible with Brimonidine.
  2. Some users will get a flush reaction that will probably mean that they will stop using Mirvaso.
  3. Next, there will be a group of rosacea sufferers who get a mild to moderate reaction but will choose to continue to use Mirvaso.
  4. Finally, and hopefully in the majority, will be a group of Mirvaso users who see a good relief in their red face.

Mirvaso Reviews

Alan says:

 Not as impressed as I hoped to be, but only on my 4th day.

dogkrazy says:

I haven’t seen any rebound, but it does wear off. I use it once a day after my shower.

At first, it gets a bit redder looking but a couple hours later it blanches out..rather like pushing your finger hard on something until the pink turns white…it looks tons better!! the less red side almost looks normal on it.

alfypet says:

I tried my Mirvaso today for the first time. I applied about 45 minutes ago. The good news is that I have not reacted badly thus far. I am so used to applying a topical and immediately getting red and flushy, so that is a big plus for me.

The area on which I applied the cream has definitely paled. Surprisingly, this does not necessarily make me look better.

and then;

The good news is that I have used it for three days now and have seen no ill effects. That is huge for me, as I usually react to everything! I can’t use Metrogel, Finacea, Promiseb, Xylogel, etc, without reacting with redness or flushing.

The Mirvaso definitely helps with diffuse redness, and I think a lot of people will have great results. Under my redness, I have visible vessels, which I was hoping would not be visible with Mirvaso. But for me, they are still visible, and no longer hidden by the redness of my overall rosacea. Honestly, had I never had laser treatment and Veinwave, which made these veins more visible, I think I’d have much better results.

I do feel, however, that applying Mirvaso takes down my rosacea, in general, a degree or two. My face feels calmer and less reactive so far. I am at work today, which will be a good test. I usually flush on a daily basis at work at around 6/7 pm. I’m not sure why, but it is probably anxiety trying to finish my deadlines and get out of the office. I’ll see if that happens today.

anon24 says:

Okay I finally picked up Mirvaso from the pharmacy. Using the savings card, I only had to pay $50 for the 30mg tube, and I don’t have a great insurance, so most folks will probably get a pretty good deal on it. I applied it in the parking lot in one spot, ran some errands, and came home, and its now been about 40 minutes. I did about a quarter sized area, and the redness has subsided a bit, but nothing to write home about. I don’t know if it starts to work more after 30 minutes, I assumed that at 30 minutes it was working at maximum ability, but I will post more updates later. It is very easy to apply, spreads very easily (it’s a clear cream, kind of like vaseline), and doesn’t feel drying or anything like that. So the redness is reduced after about 40 minutes, not nearly as much as I’d hoped, but I will update later.

Steven says:

So I got it – about a week ago – used it 4 days – looked great at first, then seemed to have some breakthrough redness before the 12 hours were up. Thought I would stop using it for a few days as I thought I might be developing tolerance to it. The day after I discontinued it my face has been flushed more than before I used it. So rebound redness seems to be potential problem – It certainly has been for me.

wiry says:

Early Review: I tried it on the entire face. I took about 45min-1hr to kick in.

– The forehead results seem to be pretty decent.
– Cheeks were blotchy. Some spots were too pale, which increased contrast from the redder areas.

I think my cheeks looks worse with Mirvaso because it was just too blotchy. Some areas are too pale and unnatural looking. Have you ever heard someone say you look like you’ve seen a ghost? Well, it sort of looks like that. The forehead seemed to give a better cosmetic result. Perhaps with some experimentation one could get it look better. I will try some different approaches and see what happens.

Overall, I think with enough experimentation (and fingers crossed there is no rebound flushing), this could be a useful medication. But I think it will be tricky to really good natural looking results (at least for me). Its a little “black and white” or should I say “red and white”. Maybe if I were to dilute it a little and just go for a toning down of redness, it would be better.

littlelassie says:

This is my third day using Mirvaso and my first day to apply it in the morning instead of the afternoon. Today isn’t the greatest test because I also used little makeup since I was going to be with other people all morning and am a chicken. Interestingly enough I haven’t seen the same degree of effectiveness the past two days, but I believe that’s either because I am using less than the first time or because I have started mixing it with Cerave lotion to help it spread more easily. That being said, my redness has mostly disappeared by 45 minutes after application, I just don’t look freakishly pale. The one thing that bothers me is that at around 5-6 hours I start to see some pink/red coming back. All three days the redness first appears in my t-zone. I think it might have something to do with my skin becoming oily?

Matt_Seattle says:

Test Patch Review:

Well Mirvaso definitely works (at least it did for me). I first applied it just to a section on my nose and it turned it completely pale in that area (took about 20 minutes for the effect). There was no stinging and it applies smoothly (no scent really either) the texture reminds me a bit of cetaphil moisturizer or Cerave PM.. Very thin and easy to absorb. Now after the first application and as others described, it almost looked like an obvious pale spot with surrounding pinkness, but after taking a tiny bit more, working it through the finger tips and lightly applying to the rest of my nose while trying to fade it lightly into my cheeks, it smoothed out and gave a natural pale complexion to my nose. Im pretty impressed with how good it actually works.

Acanthous says:

I used 3 pea-sized blobs for whole face, at 2pm on the day I got the script ($50 w/coupon). I am a flusher, with many, many triggers, including ‘being alive’ and ‘breathing’. Deepest flushing is on nose and cheeks, but rest of face, neck and chest also flush. I always have some redness. Observations:

– I was white like a vampire for approximately 14-15 hrs. Not even red wine and pasta made the treated areas flush.
– this is not as good a look as I imagined it would be. Also, it highlighted the neck and chest flushing I have.
– some normal flushing started coming back on face and cheeks around 8am the next day.
– extreme, weird rebound flushing on cheeks starting by 9 am. Deep, blotchy flush, very hot and uncomfortable.

Renae says:

I have used mirvaso for the past three nights and the results are amazing!!!!!!! The redness/burning/swelling is totally gone! I do look pale in comparison to my normally flush appearance but i couldnt be happier with the results. I’m going to not use it for a few days and see what happens. Has anyone else had the same results as I have?

redman says:

Got it today. Left the Drs office, washed face, applied. 20 minutes later I walk in the house and my wife tells me I look pale. Not pale, I tell her. This is my correct color and that she should try it as well.

Renae says:

I just tried mirvaso and I cannot believe the difference it made with the redness/telangiectasias!!!!! I’ve tried every cream(finacea, metrolotion, oracea etc).

Scotty says:

Hi All – got a sample of Mirvaso yesterday from my Dr.  I used it for the first time this morning after my shower.  Didn’t really think much about it (had little faith to be honest) until I went to the restroom at my office.  Looked in the mirror and was very impressed!  It usually takes a long time for my skin to “settle down” after a shower etc – but my redness was VERY improved!  I still can’t believe the results.  So far I’m a fan.  We’ll see how it goes.  Good luck!

GreenGables says:

Using Mirvaso for 3 weeks. My derm recommended it at my appointment last month. I hadn’t heard of it before. But my derm is fairly on top of new treatments, and she said she’s had positive reports from her other patients since it came out in September.

Maybe that will change the longer I use it, but right now it’s positive for 3 weeks and counting.

and

I have been using Mirvaso for 3 weeks without any rebound flushing. Of course it all could change at some point, but so far it has worked for me.

Please Leave a Comment

If you have tried Mirvaso, please leave us a comment below so that we can all get to see how well it is going as a treatment – thanks!

Rebound Redness

There is a growing body of reports of bad flushing reactions to Mirvaso. It isn’t yet clear why this is; that it appears that users are having bad reactions to Mirvaso a higher rate than was seen in the Phase 3 long term trials. Take care and work with your doctor if you think you might be worse off after using Mirvaso.

So please do let us know in the comments below whether you stick with Mirvaso or have to stop using it.

Related Articles

About the Author

About the Author: David Pascoe started the Rosacea Support Group in October 1998. .

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591 Reader Comments

  1. Robert says:

    I tried it and can not recommend it to anyone. The first day I thought I was in heaven, it worked like a charm. The second day, same thing … UNTIL IT WORE OFF .. I had the WORST red, flush episode EVER that was constant and flarring for 2 days. I hid. I cringe at the thougth of using it again.

  2. kate C says:

    I have been using it now for one week. First day the result was magical but since then it’s awful. Burning skin and even more redness than before I started. For example now have a red chin (which I never had) which now joins the flushing on my face to some extended flushing on my neck. Embarassing. Time to stop its use sadly…

    • Sandra L. Keamer says:

      My face became a flaming volcano after using it. It was a horrible experience. I urge anyone to be very careful using Mirvaso.

  3. CathySullivan says:

    I have used this product for four days and found some relief ( I had a mild case). On the fifth day I experieced flushing which I have never experience before. I stopped using the product for two days and I am still experiencing extreme rebound flushing. The flushing and redness is worse than before, and so very uncomfortable! I put on hyrdrocortisone cream 1%, a cool beverage, and a fan on my face seems to help a bit.
    Tomorrow, I will be calling my derm and tell him not to prescribe this medication to those who have very fair and sensitive skin.
    I do hope the flush will go away, and not damage my skin permanently.

  4. Florinda says:

    I’ve been on Mirvaso for about a month now. I don’t seem to have a reaction to it when I don’t use it. It does help with the swelling, redness and acne like breakouts. The breakouts disappear when I use it. I use it in the morning and it lasts about 10 hours. I’m also using Zyxal for the itching but even the itching goes away when I use Mirvaso. I will continue to use Mirvaso. I’ll write an update in about a month to see if Mirvaso is still working.

    • Ann Halpin says:

      I’ve been using Mirvaso for the past five months and as long as I use a pea sized amount for my entire face it works great. I am having an outbreak at the moment but that is due to stress and and eating two trigger foods (my fault). I think for those for whom it doesn’t work there are other options. I had tried Metrogel and Finecia first. Metrogel didn’t completely work and the Finecia completely burnt my skin. We just all have to find what works for our own skin.

  5. xdhzx says:

    Made redness and flushing so much worse from the start! Initially it took a little redness away for maybe an hour or so then came the worst flushing, blotchy skin and redness I have had in years. I thought maybe my skin needed to get used to it. I mixed it with moisturizer and sunscreen that I tolerate very welll as other had suggested but everything became a trigger and sent my face, neck and chest into such horrible flushing I had to leave work more than once. I’ve stopped using it for three days and it’s still happening. I know my face is more red because I did take photos. Mirvaso was a complete failure for me. I’ve made and appointment to have V-beam laser treatment in hopes of reversing the damage.

  6. Mark says:

    I have used Mirvaso for 6 days now. The first 4 days were great I could not believe how it reduced my redness, and the gel lasted nearly 12 hours. Now the last 2 days have been a nightmare, 10 hours in and my face started burning like fire. The worst thing about it was I was at work whilst it happened. I went for a walk outside to try and cool down, but soon as I stepped back in work I was burning up dark red. Then my workmates were looking at me which made it even worse. I just wanted to run and hide but I had to keep my machine at work running. The flushing lasted over 3 hours, then calmed down. I had never had flushing like this before I had started on the Mirvaso gel. So as from now I am not using it any more. I just wanted to share this to make others aware what this could do to you. I was just so fed up with my Rosacea that I had to try it. But please be careful and think about the rebound flushes before you start using it.

  7. Jay says:

    The first 2 days Mirvaso worked just fine, but then it just made my face worse! It completely changed my life, I just wish I had never started using it.
    When I put it on, the redness slightly decreases as Mirvaso is fresh, but it only lasts 30 minutes or less! If I go into a place, for example a classroom (I’m a 18 year old teenager, I’m still studying), my face just starts burning like hell, just like Mark said above, my face turns dark red, like a tomato… I can’t ask to go outside to get some air or anything and schools are full of people, it’s so uncomfortable. I can’t stop thinking about it which makes it even worse. The flushing, redness, burning sensation have gotten really worse since I started using Mirvaso.

    • Arthur. says:

      I think 95% of folks who have used Mirvaso have had very bad reactions , me included . I was very excited when I first applied Mirvaso , then two hours later my face looking like a Stop light . If only galderma could sort out this rebound Flushing thing , but until then I will NOT be putting their Mirvaso anywhere near my skin and I would advise anyone who has thought about trying it …DON,T !!!!

      • Stuart says:

        Thanks Arthur and Jay. My feelings exactly. In fact, after I reported in to my doctor, he told me to throw away all the samples he had given me

        • Jay says:

          I’m just afraid of stop using it, that’s why I haven’t yet. I think it has a ”psychological impact” or so, at least, once I put it on I just think ”Ok, I have Mirvaso on, there’s nothing I should worry about” but then my face just turns hot and it feels like I’m in hell.
          I’m trying to convince my mom to take me to see my derm again as it’s kind of expensive… otherwise I’ll just stop using it during winter break.

  8. Sarah Jane Dawson says:

    I absolutely couldn’t wait to start using my Mirvaso cream and was totally buzzing as it began to work on day one . Day two I had a stressful day in hospital ,, it was so hot the heating up on full and still my face stayed calm ,cool and fairly pale . However day three was not good ,, my face felt hot and throbbing , still not as red as normal but other parts of my face not normally effected by flushing started to turn red . It’s now day five and I,ve completely stopped using it . What I thought was the answer to all my dreams is now my worst nitemare . My entire face is bright red and burning all day long . Areas that were never problem areas are now permanently a very dark sinister colour . Please think carefully before using this cream . I,m hoping my face will calm down . I ,m even waking up with a severe flair up that has never happened before . This is not good

    • Sarah Jane Dawson says:

      Does anyone have any experience of the rebound flushing lasting a long time after using Mirvaso cream . I haven’t used it for a few days but my face is red ,, hot ,, blotchy ,,the worst flushing I,ve had with no triggers involved x

    • Kari says:

      try mixing a LITTLE BIT of Mirvaso with moisturizer or anti histamine cream before applying. Its probably too strong for you straight from the tube.

    • Mel says:

      I have the same problem. It is heartbreaking and my skin is worse than when I started using this crap stuff.

  9. I'm sad says:

    I hate my rosecea, It mates me depressed, reclusive I would do anything to have clear skin, suicidal thought, and kills my skills with the lady’s, heard some good reveiw and some bad ones about mivarso going to try it will let you know how I get on.

  10. Mel says:

    First 2 days I was so very happy with results. I looked normal again. Day 3 progressively got worse. My skin is now worse than ever. $90 A TUBE!! Can’t believe I got sucked in. I have now not used the cream for a week and my skin burns constantly and is redder than ever.

  11. Dan says:

    Mirvaso-
    Used the creme for a couple of months with an overall good result. Then began to suffer impetigo after even brief use. I thought I was being careless with it, so I doubled down on washing, clean application, etc., but no use. Now I use it maybe 8x a year, but I have to deal with impetigo breakouts for 2 weeks afterward. Anyone have any suggestions? Thanks.

  12. David Strackbein says:

    I used Mirvaso for 3 weeks and had great success and all redness is gone and no side effects.

  13. Shelia Butts says:

    I use the Mirvosa each time I am leaving home and although it softens the redness and even seems to fade some of the breakout and scarring, it is short-lived. Within a few hours it wears off and my beacon “Rudolph” is shining again. The only thing I have noticed which may or may not be as a result of the Mirvosa is the little whiteheads under my skin on my cheeks seems to be worse. If it were not for these whiteheads and large, extremely clogged pores in my nose and chin, I would actually have clear skin.

  14. Douglas says:

    If you’ve had a severe rebound, read this!

    So, I’ve been on Mirvaso for well over a year now. My rebound reactions randomly started getting worse to the point I was waking up every single day with a level 10 redness. Bright, bright, all the way around, red. I started trying a multitude of regimens and nothing seemed to work. Then one day I was browsing on Amazon and found the 2 greatest products I’ve ever purchased: Apple Cider Vinegar and Aztec Secret Indian Healing Clay.

    Based off the Amazon reviews alone, I decided to purchase these 2 with little hopes and high desperation. After 2 weeks, my rebound reactions have COMPLETELY VANISHED!! I went from level 10 red every single day and wanting to shoot myself in the face, down to no rebound reaction of any kind. It started to improve after a few days, and gradually over 2 weeks got better and better to the point it’s completely gone.

    I don’t know exactly makes it workt, but here’s what I’m doing:
    ACV: Drink 2 shots of ACV daily. 1 shot in the morning, and 1 shot at night. The shots are worse than vodka, but as I’m sure you’re on here for the same reason I am, you’ll get over it once you realize the benefits. Chasing with some thick juice really helps.

    Clay mask: I mix ACV with the clay in a zip lock bag and use it for 3-4 days and make some more. I put the mask on every morning with my fingertips. Simply stick your hand in the bag and smear on your face. Wait 10-12 mins and jump in the shower (drop a deuce while you wait). After you get out, you have about a 60 minute window of normal and regular skin like you’ve never seen before. After 60 mins, your skin is still great and you already passed the “settle down” period. I still use mirvaso and my skin is completely red free 24/7!! Though, I didn’t stop there. After I jump out of the shower, I mixed my daily face moisturizer with ACV and tossed it on my face. As a cleanup toner and to kill off the shine, I used OC 8 matte finish. In all my years of hating my skin and redness, I have never been to the point of complete freedom and confidence that I am now. Truly a blessing. I really hope this review can help someone. These products are all natural and cheaper than any other “rosacea” product other there.

    One other thing to note.. I have the worst combo and acne prone skin ever.. along with some eczema. Well my friends, after 2 weeks, all that crap cleared up too. All my close friends and girlfriend have asked me what the hell I did haha. I put my eczema cream, and acne spot treatment in storage. Don’t need them!

    Links (total $12 for both!):
    Clay: http://www.amazon.com/gp/product/B0014P8L9W/ref=oh_aui_detailpage_o03_s01?ie=UTF8&psc=1
    ACV: http://www.amazon.com/gp/product/B001I7MVG0/ref=oh_aui_detailpage_o01_s00?ie=UTF8&psc=1

  15. Stephanie says:

    I just started using Mirvaso and so far it has worked great. I only put it on my nose…I never knew I had freckles on my nose. Hoping it continues to work well.

  16. Will says:

    Okay.. so I haven’t yet tried Mirvaso myself but after reading these comments I have to put my opinion out there. I’m a medical student, not a doctor (yet, or dermatologist), but from what I know it seems like a lot of these bad/rebound effects users are experiencing may be due to misapplication of the cream and not avoiding normal triggers:

    1) If you are using enough to make your face completely pale, you are using too much! Dilute with a lotion or use much less Mirvaso… The point of any medication should be to improve your symptoms, not treat them so aggressively that you go past an acceptable improvement. So… I would start slow and increase the amount applied each day until my redness is reduced to an amount I was happy with/ felt acceptable. Even if this means that slight redness is still somewhat present. Applying a TON of cream and getting pale should not the goal and it is not the purpose of this drug… Doing this will produce rebound flushing like so many other vasoconstrictors when used in excess….

    2) If the medication is supposed to be applied only once per day.. follow the instructions!!! Yes, that might mean that if you want to reduce redness at night for a party, you won’t be able to use it that morning for when you go to work. But that is a tradeoff you need to make. Many vasocontrictors on the market today, for other diseases, also have a limit to how often you can take them because overuse (even in the smaller amounts that I described above) can ultimately lead to rebound.

    2) I keep seeing posts describing how “the first time I used Mirvaso, not even red wine or sun (or whatever my old triggers were) caused me to flush!!!” And then they wake up the next day with horrible “rebound” flushing… In my opinion this is not rebound flushing at all. This is what happens when you spend a day ignoring what you know about your rosacea and start experimenting with all of your triggers.. I myself know that red wine or alcohol or spicy food late at night will absolutely give me a bad complexion the next day! Remember, Mirvaso is not preventing the release of histamines (inflammatory signals) in your body that normally cause redness.. those things are still released. All Mirvaso does is temporarily prevents your blood vessels from dilating in response to the inflammatory signals. So… when the medication wears off the next day you can bet that your face will not be happy. So AVOID TRIGGERS even when using Mirvaso!!!! Even if you think that your lack of symptoms in moment must mean you’re invincible to them, because you’re not!

    I’m sure many of you have followed these pieces of advice already.. but for those of you who haven’t it might improve the success rate of this cream.

    • Ann says:

      Excellent points! My dermatologist told me to use a pea size amount for the whole face, rather than a pea size amount for each area (Mirvaso instructions). While following that advise I have never had an issue with Mirvaso. Once I decided to follow the med instructions and that definitely was not a good idea! The only time I have flare-ups or “rebound redness” now is when I eat or do something that I know is a trigger. We all want a miracle that will allow us to do whatever we want without repercussions, but that is not realistic.

  17. Joan says:

    My derm gave me some small sample tubes only saying to use it on the red areas and that it would definitely work. I tried it out before going to an evening symphony performance. Didn’t use much but was shocked to see perhaps a half hour later that I had gone completely white where I had applied it–but I looked ridiculous because the parts I hadn’t touched looked super red in comparison. So I had to cover those spots too with a thin layer and in about 45 min. I was completely white.

    While I found it fascinating to see how pure white I could look so quickly I honestly thought I looked rather sickly. Also, more disturbing was that the entire evening I felt like my face was deeply flushed even though there was no evidence of it. I kept asking my companions if my face was flushed because it felt so hot–but it didn’t look it at all.

    I think Mirvaso is interesting but I don’t see how it can be called a medication. It seems to be like a temporary eraser for the redness, but just like Cinderella, you’re going to go back to your former state in a few hours. My cosmetics can do a better job without the unpleasant sensation and the deathly whiteness.

    • Jo says:

      The previous points from WIll are EXCELLENT! I too have been experimenting with different amounts of Mirvaso and agree with Will that one should use the minimal amount of any medication to treat symptoms. By doing this, I have been using Mirvaso successfully for over a year now.

      With regard to Joan above, Mirvaso IS a medication used to treat redness and flushing just like say, hypertensive medications. If you stop a hypertensive medication, your blood pressure will return to its elevated level the next day. Their effects are “temporary” as well, yet millions of people continue to take them daily.

      Joan, try using a lot less Mirvaso or weaker concentration to avoid over-whitening. Good luck and Happy Holidays!

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