Recent Posts

Severe Mirvaso Rebound Redness: Dermatitis Medicamentosa

(Click image for a larger view). (Left) One hour following application of Mirvaso with initial blanching and improvement of baseline erythema. (Right) Twelve hours following application of Mirvaso with significant increase in baseline erythema. A recently published short article in Dermatology Online Journal is proposing the use of the term Dermatitis Medicamentosa to describe one […]

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Honevo Kanuka Honey proven to help Rosacea Sufferers

A poster session at the just completed 2015 AAD Meeting in San Francisco has published some results that show a special formulation of Kanuka Honey is able to benefit rosacea sufferers. The information around this announcement tells us that a `large clinical trial has proved that Honevo, a medical grade kanuka honey formulation, developed by […]

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A session at the recent 2015 AAD meeting in San Francisco offered the following summary of the status of the development of the Finacea Foam product. Probably the most interesting new bit of information is that Finacea Foam is expected to approved in August this year. What’s New in Rosacea Therapy? Zoe Diana Draelos, MD […]

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Galderma has announced that Soolantra has been approve across the 28 European Member States. Soolantra was approved in the US by the FDA in December 2014, so the European approvals took just an additional 3 months. Galderma Announces Positive Outcome of European Decentralised Procedure for Approval of SOOLANTRA (ivermectin) Cream 10mg/g for Rosacea Patients MARCH […]

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A clinical research company has posted a large clinical trial to compare a Metronidazole 1% Gel to Galderma’s Metrogel 1%. The multi center trial is looking for 947 participants across the US. The manufacturer of the comparison Metronidazole 1% Gel is not mentioned, but a reasonable guess would be Metronidazole Gel from Sandoz. Generic Metronidazole […]

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Genetic link to Rosacea Cause Gets Closer

In the quest to describe and therefore being able to control rosacea, the list of possible causes has been long and diverse. Think yourself of all of the possible causes that you yourself have encountered, for eg; demodex mites, excessive sun, alcohol, helicobacter pylori, SIBO, cathelicidin. Only recently have researchers been able to make progress […]

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Mirvaso

Severe Mirvaso Rebound Redness: Dermatitis Medicamentosa

(Click image for a larger view). (Left) One hour following application of Mirvaso with initial blanching and improvement of baseline erythema. (Right) Twelve hours following application of Mirvaso with significant increase in baseline erythema. A recently published short article in Dermatology Online Journal is proposing the use of the term Dermatitis Medicamentosa to describe one […]

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Mirvaso in the real world: 10-20% have rebound redness

This just published paper in the Journal of Drugs in Dermatology has an interesting statement that is an admission that Mirvaso in the real world is not performing as well as seen in the Phase III Clinical Trials. This fact will come as no surprise to those following the online reviews for Mirvaso – there […]

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Actavis to trial Mirvaso competitor

An interesting development in rosacea clinical trials is the emergence of a new company called Actavis. Actavis have listed a large trial where they plan to test their Brimonidine Gel against Galderma’s recently FDA approved Brimonidine-based Mirvaso Gel. The large Phase 3 trial will compare the response after 7 days. Up to 462 patients in […]

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Galderma offers physicians advice for Mirvaso Rebound Redness

Galderma have added a page to the Mirvaso web site to guide doctors dealing with the potential for “rebound” by users of Mirvaso. This would seem to confirm that Galderma is aware that there are users of MIRVASO who are experiencing adverse events. The use of double quotes around “rebound” and “worsening” is interesting and […]

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Demodex Mites

Simply No Proof that Demodex Mites cause Rosacea

Now you are talking ! Finally a paper that comes right out and says in a clear way that there is simply no proof that demodex mites cause rosacea. OK, they don’t say it quite so succintly as that – here is the conclusion; Demodex mites can be regarded as a non-necessary, non-sufficient causal factor […]

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Another Demodex Bacteria Isolated: Bartonella quintana

In a short paper, researchers have detailed the investigation into demodex mite bacteria that was able to isolate another pathogenic bacteria. This time the bacteria is known as Bartonella quintana. B. quintana can now join B. oleronius bacteria directly linked to demodex mites. Here is what you need to know.

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More Demodex Mite Peculiarities

With all of the terrible articles you can find on the net about demodex mites (delighting to tell us about about how they eat, defecate and reproduce in your skin; and how they are actually `spiders’) it is nice to read a well written article full of real facts about demodex mites. You Almost Certainly […]

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Cliradex T4O wipes for treating Eye Lash Mites

In mid 2012 we learned that a company called Tissue Tech was going to trial single use T4O wipes as a treatment for ocular demodex mites. Early last year Bio-Tissue Inc., the parent company of Tissue Tech announced the release of Cliradex. This new product is promoted as a tea tree oil based moist towelette […]

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Oracea

Say goodbye to Generic Oracea

A recent ruling from the U.S. Patent and Trademark Office has put the final nail in coffin of the hopes for the availability of Generic Oracea. Rosacea sufferers will need to wait until that late 2020’s until the current patents protecting Oracea expire. Concerted efforts from Amneal Pharmaceuticals and Mylan Inc. have both failed to […]

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Step backwards for Generic Oracea. Invalid patents are back

For those following the saga of the possible availability of Generic Oracea in the future, another twist today. Two of the patents that were previously ruled invalid and thus unable to protect Galderma’s product, have now been ruled no longer invalid. This legal ruling will no doubt embolden Galderma that their profitable product Oracea can […]

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Generic Oracea one step closer, Lupin gets Tentative FDA Approval

News today that Lupin has been granted tentative approval by the FDA to product a generic version of Oracea. We learn in 2010 that Lupin had filed an abbreviated new drug application to make generic Oracea. Lupin Pharmaceuticals, based in Mumbai India,  is a company specialising in the production of generic medicines. It has been […]

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Indian Pharma may allow Generic Oracea

There is always a lot going on in the world of BigPharma. A recent court case in India suggests that the Indian Government will allow local manufacturers to produce generic versions of in-patent drugs that are simple derivatives of existing drugs. India’s law restricts pharmaceutical companies from obtaining new patents for small modifications to existing […]

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Natural Treatments

Honevo Kanuka Honey proven to help Rosacea Sufferers

A poster session at the just completed 2015 AAD Meeting in San Francisco has published some results that show a special formulation of Kanuka Honey is able to benefit rosacea sufferers. The information around this announcement tells us that a `large clinical trial has proved that Honevo, a medical grade kanuka honey formulation, developed by […]

Continue Reading

East Indian Sandalwood Oil in Benzac Acne Solutions

A local angle for an Australian commercial producer of East Indian Sandalwood Oil. West Australian based TFS is touting its supply of East Indian Sandalwood Oil to Galderma for use in the just released over the counter Benzac Acne Solutions product. TFS is said to be the world’s only supplier of pharmaceutical-grade sandalwood oil, and […]

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Cliradex T4O wipes for treating Eye Lash Mites

In mid 2012 we learned that a company called Tissue Tech was going to trial single use T4O wipes as a treatment for ocular demodex mites. Early last year Bio-Tissue Inc., the parent company of Tissue Tech announced the release of Cliradex. This new product is promoted as a tea tree oil based moist towelette […]

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Rutin Forte Supplement reduces redness apparently

A paper published in the Georgian Medical News, and listed on PubMed details a study that concludes that Rutin Forte is an effective means for the treatment and prevention of erythematous rosacea. The supplement was included alongside regular rosacea therapy of topical and oral antibiotics. What is Rutin Forte? Rutin Forte is a nutritional supplement […]

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Metrogel

A clinical research company has posted a large clinical trial to compare a Metronidazole 1% Gel to Galderma’s Metrogel 1%. The multi center trial is looking for 947 participants across the US. The manufacturer of the comparison Metronidazole 1% Gel is not mentioned, but a reasonable guess would be Metronidazole Gel from Sandoz. Generic Metronidazole […]

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Generic Metrogel Pump 1% from Sandoz

Despite suggestions that Generic Metrogel is easily available in the US, there are scant reports online from users getting access to cheaper Metronidazole 1% treatments. In July this year Sandoz announced that they were selling a generic version of Metrogel 1%. The generic versions of metronidazole gel were previously restricted to 0.75% as the patent […]

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Ivermectin better than Metrogel 0.75% for papules and pustules

Some just published research from the Ivermectin Phase III study group suggests that Ivermectin 1% cream once a day is better than Metronidazole 0.75% twice a day at treating the papules and pustules of rosacea. The British Journal of Dermatology paper tells us that although both Ivermectin and Metronidazole did lead to a reduction in […]

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The National Rosacea Society is 20 Years Old

A recent blog posting from the NRS has mentioned that this month the National Rosacea Society is 20 years old. NRS Celebrates 20 Years Thursday, September 6, 2012 The National Rosacea Society (NRS) marks its 20th anniversary in 2012, and is pleased to report on the vast ongoing progress that has been made toward fulfilling […]

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Fact Sheets

AARS, The Best Rosacea Topicals

The American Acne & Rosacea Society have published another paper in their series looking at the state of the art in rosacea treatments. This part is dedicated to rosacea topicals, and how to use them to manage rosacea symptoms. The paper is described as reviewing “topical agents approved by the US Food and Drug Administration […]

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Syndets and Lipid Free Cleansers, What Are They? Do They Work?

You may have come across the term Syndet or `Lipid Free Cleanser’ when researching mild cleansers. What are they, and am I missing something by not having them in my daily regime? What is a Syndet? Well the term means `Synthetic Detergent’ and is an attempt to create a cleanser that is suitable for the […]

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Rosacea Subtypes, How are they related?

So we all know the official rosacea subtypes right  ? Erythematotelangiectatic, Papulopustular, Phymatous and Ocular rosacea (Lets ignore neurogenic rosacea for now). Well, are these 4 sub types related, and in what way? Will rosacea progress in severity and can your rosacea proceed between subtypes? If we are in a question asking mood, then why […]

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How much do Rosacea Prescriptions Really Cost?

You don’t have to read the online rosacea forums for very long to see the outrage at how much rosacea sufferers, especially in the US, pay for Rosacea Prescriptions. If you want to try Metrogel 1%, Oracea or Finacea what might you expect to pay? The answer is actually not straight forward. A lot will […]

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User Reviews

Soolantra User Reviews

Even though Soolantra has only just been approved as a treatment for rosacea, and won’t be available for a couple of months, can we get any idea of how well it might work ? Thankfully the answer is yes. With credit to those who have been part of the extensive trials for Galderma’s code-named CD5024 […]

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Dermalex Repair Rosacea and Couperose Cream Reviews

Looking more like a sunscreen with some herbal extracts Dermalex Repair has made a gentle entrance to the rosacea market in the UK. Described as a `treatment cream for Rosacea and Couperose’ Dermalex seems to be a mild and reasonably priced skincare cream. The product publicity includes the following grand sounding claims’ The patented Tri-solve® […]

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ONRELTEA User Reviews

Galderma, for reasons unknown, decided to rebrand the newly FDA approved Mirvaso as ONRELTEA in Canada (yes they use all capitals in the brand name). This continues the tradition for Galderma of split North American branding; Oracea in the US is known as Efracea in Canada. There is already some history of user experiences of […]

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Cetaphil Gentle Skin Cleansing Wipes, no rinsing needed

I feel like a bit of a Galderma PR machine at the moment, but Galderma do seem to be doing a lot. Maybe this product is yet another step in Galderma’s quest  to own the Rosacea Market. So coming soon is a moist cloth version of Cetaphil Gentle Skin Cleanser. Have you ever wished that […]

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Moisturizers

Soolantra Cream is based on Cetaphil Moisturizing Cream

In the media materials released when Soolantra was announced, Galderma told us that Soolantra is based on their Cetaphil Moisturizing Cream. Soolantra Media Release Soolantra (ivermectin) Cream, 1% is a new, antibiotic-free, prescription topical treatment for the bumps and pimples of rosacea. Soolantra Cream may provide visible results as early as week two. Cetaphil Moisturizing […]

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NeoStrata Facial Cleanser and Ultra Moisturizing Face Cream

Rosacea sufferers are always on the lookup for suitable cleansers and moisturizers. One of the pearls in finding relief from rosacea symptoms is that finding a supporting and gentle cleansing and moisturizing (and protective) regime is important. A recent paper by Dr. Patricia Farris, Skin Care Based on Science: Improving Outcomes in Rosacea, tells us […]

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Bionect improves Rosacea Symptoms

A recent paper in the Journal of Drugs in Dermatology suggests that Bionect may be helpful for the symptoms of rosacea. The study found that after 4 weeks the burning or stinging and dryness of rosacea was much improved, while papules and redness were also improved. What is Bionect? Bionect is a prescription only cream, […]

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The American Academy of Dermatology has published some face-washing tips. Washing your face may seem like such a simple activity that highlighting it may feel unnecessary. For rosacea sufferers though, we know that a gentle skin care regime is important. Starting your rosacea-beating regime with an irritating cleanse is simply going to make your skin […]

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Cleansers

Cetaphil Gentle Skin Cleansing Wipes, no rinsing needed

I feel like a bit of a Galderma PR machine at the moment, but Galderma do seem to be doing a lot. Maybe this product is yet another step in Galderma’s quest  to own the Rosacea Market. So coming soon is a moist cloth version of Cetaphil Gentle Skin Cleanser. Have you ever wished that […]

Continue Reading

NeoStrata Facial Cleanser and Ultra Moisturizing Face Cream

Rosacea sufferers are always on the lookup for suitable cleansers and moisturizers. One of the pearls in finding relief from rosacea symptoms is that finding a supporting and gentle cleansing and moisturizing (and protective) regime is important. A recent paper by Dr. Patricia Farris, Skin Care Based on Science: Improving Outcomes in Rosacea, tells us […]

Continue Reading

Syndets and Lipid Free Cleansers, What Are They? Do They Work?

You may have come across the term Syndet or `Lipid Free Cleanser’ when researching mild cleansers. What are they, and am I missing something by not having them in my daily regime? What is a Syndet? Well the term means `Synthetic Detergent’ and is an attempt to create a cleanser that is suitable for the […]

Continue Reading

The American Academy of Dermatology has published some face-washing tips. Washing your face may seem like such a simple activity that highlighting it may feel unnecessary. For rosacea sufferers though, we know that a gentle skin care regime is important. Starting your rosacea-beating regime with an irritating cleanse is simply going to make your skin […]

Continue Reading

New Treatments

How does Soolantra (topical ivermectin) work?

Ahead of the expected approval and launch of Galderma’s Ivermectin 1% Cream is this abstract further highlighting the credentials of topical ivermectin. How does Ivermectin exhibit superior papule and pustule clearing abilities ? Well this paper tells us that topical ivermectin is effective because of its antimicrobial, antiparasitic, antibacterial, and anti-inflammatory activities. Galderma is expected […]

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Actavis to trial Mirvaso competitor

An interesting development in rosacea clinical trials is the emergence of a new company called Actavis. Actavis have listed a large trial where they plan to test their Brimonidine Gel against Galderma’s recently FDA approved Brimonidine-based Mirvaso Gel. The large Phase 3 trial will compare the response after 7 days. Up to 462 patients in […]

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Gladskin Rosacea Cream and Gel, Staphefekt in a topical

Seeking to create products based on the recently publicised MRSA-killing topical Staphefekt are some topical creams to treat rosacea, acne, eczema and general skin irritation.

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Laropiprant (MK-0524) fails as a treatment for a red face

We don’t often get to see research results published that show a proposed new treatment doesn’t work. It make sense that researchers and pharmaceutical companies would rather see their research and development efforts succeed and lead only to new products. A clinical trial for MK-0524, Merck’s designation for their product known as Laropiprant, has confirmed […]

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