Recent Posts

Actavis to trial Mirvaso competitor

An interesting development in rosacea clinical trials is the emergence of a new company called Actavis. Actavis have listed a large trial where they plan to test their Brimonidine Gel against Galderma’s recently FDA approved Brimonidine-based Mirvaso Gel. The large Phase 3 trial will compare the response after 7 days. Up to 462 patients in […]

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Farmaka Rosacea Cream (Dermalex) Improves Redness

Further to the gentle market launch of Dermalex Repair Cream is some vendor sponsored research into how well Farmaka Rosacea Cream (FRC) treats the redness and general dryness of rosacea. So What is Farmaka Rosacea Cream?

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Gladskin Rosacea Cream and Gel, Staphefekt in a topical

Seeking to create products based on the recently publicised MRSA-killing topical Staphefekt are some topical creams to treat rosacea, acne, eczema and general skin irritation.

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Staphefekt: New antibiotic topical kills MRSA

Lots of mainstream media attention this week relating to a new type of antibiotic that is able to kill that increasingly resistant bacteria MRSA. The small patient trial was able to demonstrate that this new enzyme derived from a virus that infects bacteria, was able to clear MRSA skin infections. What does this mean to […]

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Another Demodex Bacteria Isolated: Bartonella quintana

In a short paper, researchers have detailed the investigation into demodex mite bacteria that was able to isolate another pathogenic bacteria. This time the bacteria is known as Bartonella quintana. B. quintana can now join B. oleronius bacteria directly linked to demodex mites. Here is what you need to know.

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Trial: Cutera Excel V versus Syneron Candela Vbeam

Cutera, the makers of the Cutera Excel V, a 532nm KTP Laser have posted the details of trial comparing their product with the 595nm Pulse Dye Laser from Syneron Candela. The physician and trialist will assess improvements in the blood vessels and pustules and papules of rosacea. Additionally the trial will use a Spectrophotometer to […]

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Mirvaso

Actavis to trial Mirvaso competitor

An interesting development in rosacea clinical trials is the emergence of a new company called Actavis. Actavis have listed a large trial where they plan to test their Brimonidine Gel against Galderma’s recently FDA approved Brimonidine-based Mirvaso Gel. The large Phase 3 trial will compare the response after 7 days. Up to 462 patients in […]

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Galderma offers physicians advice for Mirvaso Rebound Redness

Galderma have added a page to the Mirvaso web site to guide doctors dealing with the potential for “rebound” by users of Mirvaso. This would seem to confirm that Galderma is aware that there are users of MIRVASO who are experiencing adverse events. The use of double quotes around “rebound” and “worsening” is interesting and […]

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New adverse allergic contact reaction to Mirvaso noted in JAAD

The latest edition of the Journal of American Academy of Dermatology lists an exchange by letter detailing a contact dermatitis allergic reaction to Mirvaso. The adverse reaction was found by the doctors to be caused by the main active ingredient in Mirvaso, Brimonidine. The writers of the letter to the JAAD caution other doctors that […]

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Mirvaso Gel is now available in Australia

According to the Galderma AU web site, Mirvaso is now available in Australia. Here are the Australian versions of the MIRVASO Gel User Consumer Information and also Mirvaso Product Information. Mirvaso was first registered in the Australian Register of Therapeutic Goods on the 4th of August 2014. See the listing here – MIRVASO CMI Mirvaso […]

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Demodex Mites

Another Demodex Bacteria Isolated: Bartonella quintana

In a short paper, researchers have detailed the investigation into demodex mite bacteria that was able to isolate another pathogenic bacteria. This time the bacteria is known as Bartonella quintana. B. quintana can now join B. oleronius bacteria directly linked to demodex mites. Here is what you need to know.

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More Demodex Mite Peculiarities

With all of the terrible articles you can find on the net about demodex mites (delighting to tell us about about how they eat, defecate and reproduce in your skin; and how they are actually `spiders’) it is nice to read a well written article full of real facts about demodex mites. You Almost Certainly […]

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Cliradex T4O wipes for treating Eye Lash Mites

In mid 2012 we learned that a company called Tissue Tech was going to trial single use T4O wipes as a treatment for ocular demodex mites. Early last year Bio-Tissue Inc., the parent company of Tissue Tech announced the release of Cliradex. This new product is promoted as a tea tree oil based moist towelette […]

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Linda Stein Gold mentions in a video posted on Skin and Allergy News, referring to Galderma’s Ivermectin Cream ; Phase 3 Clinical Trials have completed, and FDA Approval is expected later this year (2014). This is great new for those who 1) want to try an approved treatment for demodex mites and 2) may not […]

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Oracea

Step backwards for Generic Oracea. Invalid patents are back

For those following the saga of the possible availability of Generic Oracea in the future, another twist today. Two of the patents that were previously ruled invalid and thus unable to protect Galderma’s product, have now been ruled no longer invalid. This legal ruling will no doubt embolden Galderma that their profitable product Oracea can […]

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Generic Oracea one step closer, Lupin gets Tentative FDA Approval

News today that Lupin has been granted tentative approval by the FDA to product a generic version of Oracea. We learn in 2010 that Lupin had filed an abbreviated new drug application to make generic Oracea. Lupin Pharmaceuticals, based in Mumbai India,  is a company specialising in the production of generic medicines. It has been […]

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Indian Pharma may allow Generic Oracea

There is always a lot going on in the world of BigPharma. A recent court case in India suggests that the Indian Government will allow local manufacturers to produce generic versions of in-patent drugs that are simple derivatives of existing drugs. India’s law restricts pharmaceutical companies from obtaining new patents for small modifications to existing […]

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Oracea launches as Apprilon in Canada

A press release today from Galderma confirms that they will be marketing the product known in the US as Oracea under the name Apprilon in Canada. All of the same precautions and prescription details for Apprilon are the same as for Oracea, i.e. it is the exact same modified-release capsule, 40 mg doxycycline. First of […]

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Natural Treatments

Cliradex T4O wipes for treating Eye Lash Mites

In mid 2012 we learned that a company called Tissue Tech was going to trial single use T4O wipes as a treatment for ocular demodex mites. Early last year Bio-Tissue Inc., the parent company of Tissue Tech announced the release of Cliradex. This new product is promoted as a tea tree oil based moist towelette […]

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Rutin Forte Supplement reduces redness apparently

A paper published in the Georgian Medical News, and listed on PubMed details a study that concludes that Rutin Forte is an effective means for the treatment and prevention of erythematous rosacea. The supplement was included alongside regular rosacea therapy of topical and oral antibiotics. What is Rutin Forte? Rutin Forte is a nutritional supplement […]

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Topical Kanuka Honey as a Rosacea Treatment

A research letter published recently in Focus on Alternative and Complementary Therapies has detailed some very early investigations into whether topical kanuka honey might be suitable as a treatment for rosacea. The trial of topical kaunka honey was conducted on 10 patients who attend a doctor’s surgery in  Tauranga, New Zealand. Patients applied medical-grade kanuka honey […]

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Alternative Rosacea Therapies – What Botanicals Work?

Why do rosacea sufferers want alternative or natural therapies? Despite the availability of several types of topical, systemic and laser therapies, and many years of research into rosacea, why is there so much ongoing interest in alternative and natural therapies ? The writers of this 2011 paper think that this is a good question, and […]

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Metrogel

Generic Metrogel Pump 1% from Sandoz

Despite suggestions that Generic Metrogel is easily available in the US, there are scant reports online from users getting access to cheaper Metronidazole 1% treatments. In July this year Sandoz announced that they were selling a generic version of Metrogel 1%. The generic versions of metronidazole gel were previously restricted to 0.75% as the patent […]

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Ivermectin better than Metrogel 0.75% for papules and pustules

Some just published research from the Ivermectin Phase III study group suggests that Ivermectin 1% cream once a day is better than Metronidazole 0.75% twice a day at treating the papules and pustules of rosacea. The British Journal of Dermatology paper tells us that although both Ivermectin and Metronidazole did lead to a reduction in […]

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The National Rosacea Society is 20 Years Old

A recent blog posting from the NRS has mentioned that this month the National Rosacea Society is 20 years old. NRS Celebrates 20 Years Thursday, September 6, 2012 The National Rosacea Society (NRS) marks its 20th anniversary in 2012, and is pleased to report on the vast ongoing progress that has been made toward fulfilling […]

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Acne seems to have a lot of available treatments. Certainly compared to rosacea, acne has a bigger array of possible treatments that have been proven to be viable treatments. One of the interesting things about rosacea is that even though it can look like acne for some, generally it cannot be treated by otherwise helpful […]

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Fact Sheets

AARS, The Best Rosacea Topicals

The American Acne & Rosacea Society have published another paper in their series looking at the state of the art in rosacea treatments. This part is dedicated to rosacea topicals, and how to use them to manage rosacea symptoms. The paper is described as reviewing “topical agents approved by the US Food and Drug Administration […]

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Syndets and Lipid Free Cleansers, What Are They? Do They Work?

You may have come across the term Syndet or `Lipid Free Cleanser’ when researching mild cleansers. What are they, and am I missing something by not having them in my daily regime? What is a Syndet? Well the term means `Synthetic Detergent’ and is an attempt to create a cleanser that is suitable for the […]

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Rosacea Subtypes, How are they related?

So we all know the official rosacea subtypes right  ? Erythematotelangiectatic, Papulopustular, Phymatous and Ocular rosacea (Lets ignore neurogenic rosacea for now). Well, are these 4 sub types related, and in what way? Will rosacea progress in severity and can your rosacea proceed between subtypes? If we are in a question asking mood, then why […]

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How much do Rosacea Prescriptions Really Cost?

You don’t have to read the online rosacea forums for very long to see the outrage at how much rosacea sufferers, especially in the US, pay for Rosacea Prescriptions. If you want to try Metrogel 1%, Oracea or Finacea what might you expect to pay? The answer is actually not straight forward. A lot will […]

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User Reviews

Dermalex Repair Rosacea and Couperose Cream Reviews

Looking more like a sunscreen with some herbal extracts Dermalex Repair has made a gentle entrance to the rosacea market in the UK. Described as a `treatment cream for Rosacea and Couperose’ Dermalex seems to be a mild and reasonably priced skincare cream. The product publicity includes the following grand sounding claims’ The patented Tri-solve® […]

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ONRELTEA User Reviews

Galderma, for reasons unknown, decided to rebrand the newly FDA approved Mirvaso as ONRELTEA in Canada (yes they use all capitals in the brand name). This continues the tradition for Galderma of split North American branding; Oracea in the US is known as Efracea in Canada. There is already some history of user experiences of […]

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Cetaphil Gentle Skin Cleansing Wipes, no rinsing needed

I feel like a bit of a Galderma PR machine at the moment, but Galderma do seem to be doing a lot. Maybe this product is yet another step in Galderma’s quest  to own the Rosacea Market. So coming soon is a moist cloth version of Cetaphil Gentle Skin Cleanser. Have you ever wished that […]

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Mirvaso User Reviews

Mirvaso is so new that only a few rosacea sufferers have been able to try it. What are your chances of having a bad reaction ? How are users in the real world faring, and will the general population see the same level of benefits as the large number of Phase III trialists ? So […]

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Moisturizers

NeoStrata Facial Cleanser and Ultra Moisturizing Face Cream

Rosacea sufferers are always on the lookup for suitable cleansers and moisturizers. One of the pearls in finding relief from rosacea symptoms is that finding a supporting and gentle cleansing and moisturizing (and protective) regime is important. A recent paper by Dr. Patricia Farris, Skin Care Based on Science: Improving Outcomes in Rosacea, tells us […]

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Bionect improves Rosacea Symptoms

A recent paper in the Journal of Drugs in Dermatology suggests that Bionect may be helpful for the symptoms of rosacea. The study found that after 4 weeks the burning or stinging and dryness of rosacea was much improved, while papules and redness were also improved. What is Bionect? Bionect is a prescription only cream, […]

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The American Academy of Dermatology has published some face-washing tips. Washing your face may seem like such a simple activity that highlighting it may feel unnecessary. For rosacea sufferers though, we know that a gentle skin care regime is important. Starting your rosacea-beating regime with an irritating cleanse is simply going to make your skin […]

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Do  BB Creams (Blemish Balm) Work for Rosacea?

What is a BB Cream? Perhaps better known to the Asian beauty market, Blemish Balm (BB) Creams are somewhat similar to a tinted moisturiser, perhaps also including some sun protection. Some formulations, especially so in Asian markets may additionally contain skin whitening agents. I’m sure all rosacea sufferers would like to think that there is […]

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Cleansers

Cetaphil Gentle Skin Cleansing Wipes, no rinsing needed

I feel like a bit of a Galderma PR machine at the moment, but Galderma do seem to be doing a lot. Maybe this product is yet another step in Galderma’s quest  to own the Rosacea Market. So coming soon is a moist cloth version of Cetaphil Gentle Skin Cleanser. Have you ever wished that […]

Continue Reading

NeoStrata Facial Cleanser and Ultra Moisturizing Face Cream

Rosacea sufferers are always on the lookup for suitable cleansers and moisturizers. One of the pearls in finding relief from rosacea symptoms is that finding a supporting and gentle cleansing and moisturizing (and protective) regime is important. A recent paper by Dr. Patricia Farris, Skin Care Based on Science: Improving Outcomes in Rosacea, tells us […]

Continue Reading

Syndets and Lipid Free Cleansers, What Are They? Do They Work?

You may have come across the term Syndet or `Lipid Free Cleanser’ when researching mild cleansers. What are they, and am I missing something by not having them in my daily regime? What is a Syndet? Well the term means `Synthetic Detergent’ and is an attempt to create a cleanser that is suitable for the […]

Continue Reading

The American Academy of Dermatology has published some face-washing tips. Washing your face may seem like such a simple activity that highlighting it may feel unnecessary. For rosacea sufferers though, we know that a gentle skin care regime is important. Starting your rosacea-beating regime with an irritating cleanse is simply going to make your skin […]

Continue Reading

New Treatments

Actavis to trial Mirvaso competitor

An interesting development in rosacea clinical trials is the emergence of a new company called Actavis. Actavis have listed a large trial where they plan to test their Brimonidine Gel against Galderma’s recently FDA approved Brimonidine-based Mirvaso Gel. The large Phase 3 trial will compare the response after 7 days. Up to 462 patients in […]

Continue Reading

Gladskin Rosacea Cream and Gel, Staphefekt in a topical

Seeking to create products based on the recently publicised MRSA-killing topical Staphefekt are some topical creams to treat rosacea, acne, eczema and general skin irritation.

Continue Reading

Laropiprant (MK-0524) fails as a treatment for a red face

We don’t often get to see research results published that show a proposed new treatment doesn’t work. It make sense that researchers and pharmaceutical companies would rather see their research and development efforts succeed and lead only to new products. A clinical trial for MK-0524, Merck’s designation for their product known as Laropiprant, has confirmed […]

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Report ONRELTEA bad reactions to Canada Vigilance Program

Users of ONRELTEA in Canada who have bad reactions or `adverse events’ related to using this newly approved product are reminded in the ONRELTEA Product Monograph to report these events. The body responsible for supervising prescription drugs is the Canada Vigilance Program. The Brimonidine based topical which is available in the US as Mirvaso has […]

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