Recent Posts

From Genetic vs Environmental Factors That Correlate With Rosacea (JAMA Dermatol) We found that approximately half of the contribution to the NRS score could be accounted for by genetics and the other half by environment. We identified correlations between rosacea and UV radiation exposure, alcohol, smoking, skin cancer history, cardiac comorbidity, and age. These findings may help […]

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Chia Seed Oil (Salvia hispanica) Also Kills Demodex Mites

There has been a bit of folklore around what substances are able to kill demodex mites. In 2008 Rosacea News published an article that listed 100% alcohol, tea tree oil, carraway oil and dill weed oil as proven to kill demodex mites. Many other substances, for example seabuckthorn oil are also claimed to kill demodex. […]

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How microbes may cause Rosacea

There are several microbial agents that appear to have their fingers in the rosacea pie; Demodex folliculorum, Bacillus oleronius, Helicobacter pylori, Staphylococcus epidermidis, and Chlamydophila pneumoniae. A 2014 paper in the Journal of the American Academy of Dermatology attempts to put the potential microbiomes into perspective. This Galderma funded paper seeks to “propose an alternative […]

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Benzac Skin Refining Mask – Salicylic Acid 0.5%

Galderma have announced a new product in the recently revamped Benzac Acne Solutions range, known as Benzac Skin Refining Mask. This product may be of interest to rosacea sufferers who want to try a Salicylic Acid based product in their regime. Long time members of the Rosacea Support Group will remember Linda Sy’s Acne Oil […]

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Finacea Foam (azelaic acid 15%) approved by the FDA

News today that the FDA has approved the azelaic acid based Finacea Foam. FDA Approves Bayer’s Finacea (azelaic acid) Foam, 15% for the Topical Treatment of the Inflammatory Papules and Pustules of Mild to Moderate Rosacea WHIPPANY, N.J., July 31, 2015 /PRNewswire/ — Bayer HealthCare today announced that the U.S. Food and Drug Administration (FDA) […]

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Soolantra launches as Rosiver in Canada

Continuing its tradition of launching new prescription products with names unique to Canada, Galderma Canada has announced that the Ivermectin based treatment known as Soolantra in the US will be known as Rosiver in Canada. In Canada, Mirvaso is known as ONRELTEA, and Oracea is known as Apprilon. The full product monograph, including the consumer notes […]

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Mirvaso

Compensatory Flushing with Mirvaso: JAMA Dermatology

LEFT: Patient at initial clinic visit after 7 months of brimonidine treatment showing compensatory vasodilation and flushing in untreated areas of right lateral cheek and chest. RIGHT: Patient 1 week after cessation of brimonidine treatment showing marked improvement in compensatory vasodilation and flushing. A brief observation published in the Journal of American Medical Association Dermatology […]

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Galderma defending against Actavis Generic Mirvaso

Following on from the large trial announcement by Actavis last year, Galderma has started a suit against Actavis to prevent the sale of Generic Mirvaso. Actavis has filed an abbreviated new drug application with the FDA. Galderma is seeking to use a series of patents to block Actavis from marketing their Brimonidine Topical Gel, 0.33%. […]

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Severe Mirvaso Rebound Redness: Dermatitis Medicamentosa

(Click image for a larger view). (Left) One hour following application of Mirvaso with initial blanching and improvement of baseline erythema. (Right) Twelve hours following application of Mirvaso with significant increase in baseline erythema. A recently published short article in Dermatology Online Journal is proposing the use of the term Dermatitis Medicamentosa to describe one […]

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Mirvaso in the real world: 10-20% have rebound redness

This just published paper in the Journal of Drugs in Dermatology has an interesting statement that is an admission that Mirvaso in the real world is not performing as well as seen in the Phase III Clinical Trials. This fact will come as no surprise to those following the online reviews for Mirvaso – there […]

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Demodex Mites

Chia Seed Oil (Salvia hispanica) Also Kills Demodex Mites

There has been a bit of folklore around what substances are able to kill demodex mites. In 2008 Rosacea News published an article that listed 100% alcohol, tea tree oil, carraway oil and dill weed oil as proven to kill demodex mites. Many other substances, for example seabuckthorn oil are also claimed to kill demodex. […]

Continue Reading

How microbes may cause Rosacea

There are several microbial agents that appear to have their fingers in the rosacea pie; Demodex folliculorum, Bacillus oleronius, Helicobacter pylori, Staphylococcus epidermidis, and Chlamydophila pneumoniae. A 2014 paper in the Journal of the American Academy of Dermatology attempts to put the potential microbiomes into perspective. This Galderma funded paper seeks to “propose an alternative […]

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Simply No Proof that Demodex Mites cause Rosacea

Now you are talking ! Finally a paper that comes right out and says in a clear way that there is simply no proof that demodex mites cause rosacea. OK, they don’t say it quite so succintly as that – here is the conclusion; Demodex mites can be regarded as a non-necessary, non-sufficient causal factor […]

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Another Demodex Bacteria Isolated: Bartonella quintana

In a short paper, researchers have detailed the investigation into demodex mite bacteria that was able to isolate another pathogenic bacteria. This time the bacteria is known as Bartonella quintana. B. quintana can now join B. oleronius bacteria directly linked to demodex mites. Here is what you need to know.

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Oracea

Say goodbye to Generic Oracea

A recent ruling from the U.S. Patent and Trademark Office has put the final nail in coffin of the hopes for the availability of Generic Oracea. Rosacea sufferers will need to wait until that late 2020’s until the current patents protecting Oracea expire. Concerted efforts from Amneal Pharmaceuticals and Mylan Inc. have both failed to […]

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Step backwards for Generic Oracea. Invalid patents are back

For those following the saga of the possible availability of Generic Oracea in the future, another twist today. Two of the patents that were previously ruled invalid and thus unable to protect Galderma’s product, have now been ruled no longer invalid. This legal ruling will no doubt embolden Galderma that their profitable product Oracea can […]

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Generic Oracea one step closer, Lupin gets Tentative FDA Approval

News today that Lupin has been granted tentative approval by the FDA to product a generic version of Oracea. We learn in 2010 that Lupin had filed an abbreviated new drug application to make generic Oracea. Lupin Pharmaceuticals, based in Mumbai India,  is a company specialising in the production of generic medicines. It has been […]

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Indian Pharma may allow Generic Oracea

There is always a lot going on in the world of BigPharma. A recent court case in India suggests that the Indian Government will allow local manufacturers to produce generic versions of in-patent drugs that are simple derivatives of existing drugs. India’s law restricts pharmaceutical companies from obtaining new patents for small modifications to existing […]

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Natural Treatments

Chia Seed Oil (Salvia hispanica) Also Kills Demodex Mites

There has been a bit of folklore around what substances are able to kill demodex mites. In 2008 Rosacea News published an article that listed 100% alcohol, tea tree oil, carraway oil and dill weed oil as proven to kill demodex mites. Many other substances, for example seabuckthorn oil are also claimed to kill demodex. […]

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Honevo Kanuka Honey proven to help Rosacea Sufferers

A poster session at the just completed 2015 AAD Meeting in San Francisco has published some results that show a special formulation of Kanuka Honey is able to benefit rosacea sufferers. The information around this announcement tells us that a `large clinical trial has proved that Honevo, a medical grade kanuka honey formulation, developed by […]

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East Indian Sandalwood Oil in Benzac Acne Solutions

A local angle for an Australian commercial producer of East Indian Sandalwood Oil. West Australian based TFS is touting its supply of East Indian Sandalwood Oil to Galderma for use in the just released over the counter Benzac Acne Solutions product. TFS is said to be the world’s only supplier of pharmaceutical-grade sandalwood oil, and […]

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Cliradex T4O wipes for treating Eye Lash Mites

In mid 2012 we learned that a company called Tissue Tech was going to trial single use T4O wipes as a treatment for ocular demodex mites. Early last year Bio-Tissue Inc., the parent company of Tissue Tech announced the release of Cliradex. This new product is promoted as a tea tree oil based moist towelette […]

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Metrogel

A clinical research company has posted a large clinical trial to compare a Metronidazole 1% Gel to Galderma’s Metrogel 1%. The multi center trial is looking for 947 participants across the US. The manufacturer of the comparison Metronidazole 1% Gel is not mentioned, but a reasonable guess would be Metronidazole Gel from Sandoz. Generic Metronidazole […]

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Generic Metrogel Pump 1% from Sandoz

Despite suggestions that Generic Metrogel is easily available in the US, there are scant reports online from users getting access to cheaper Metronidazole 1% treatments. In July this year Sandoz announced that they were selling a generic version of Metrogel 1%. The generic versions of metronidazole gel were previously restricted to 0.75% as the patent […]

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Ivermectin better than Metrogel 0.75% for papules and pustules

Some just published research from the Ivermectin Phase III study group suggests that Ivermectin 1% cream once a day is better than Metronidazole 0.75% twice a day at treating the papules and pustules of rosacea. The British Journal of Dermatology paper tells us that although both Ivermectin and Metronidazole did lead to a reduction in […]

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The National Rosacea Society is 20 Years Old

A recent blog posting from the NRS has mentioned that this month the National Rosacea Society is 20 years old. NRS Celebrates 20 Years Thursday, September 6, 2012 The National Rosacea Society (NRS) marks its 20th anniversary in 2012, and is pleased to report on the vast ongoing progress that has been made toward fulfilling […]

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Fact Sheets

AARS, The Best Rosacea Topicals

The American Acne & Rosacea Society have published another paper in their series looking at the state of the art in rosacea treatments. This part is dedicated to rosacea topicals, and how to use them to manage rosacea symptoms. The paper is described as reviewing “topical agents approved by the US Food and Drug Administration […]

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Syndets and Lipid Free Cleansers, What Are They? Do They Work?

You may have come across the term Syndet or `Lipid Free Cleanser’ when researching mild cleansers. What are they, and am I missing something by not having them in my daily regime? What is a Syndet? Well the term means `Synthetic Detergent’ and is an attempt to create a cleanser that is suitable for the […]

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Rosacea Subtypes, How are they related?

So we all know the official rosacea subtypes right  ? Erythematotelangiectatic, Papulopustular, Phymatous and Ocular rosacea (Lets ignore neurogenic rosacea for now). Well, are these 4 sub types related, and in what way? Will rosacea progress in severity and can your rosacea proceed between subtypes? If we are in a question asking mood, then why […]

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How much do Rosacea Prescriptions Really Cost?

You don’t have to read the online rosacea forums for very long to see the outrage at how much rosacea sufferers, especially in the US, pay for Rosacea Prescriptions. If you want to try Metrogel 1%, Oracea or Finacea what might you expect to pay? The answer is actually not straight forward. A lot will […]

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User Reviews

Soolantra User Reviews

Even though Soolantra has only just been approved as a treatment for rosacea, and won’t be available for a couple of months, can we get any idea of how well it might work ? Thankfully the answer is yes. With credit to those who have been part of the extensive trials for Galderma’s code-named CD5024 […]

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Dermalex Repair Rosacea and Couperose Cream Reviews

Looking more like a sunscreen with some herbal extracts Dermalex Repair has made a gentle entrance to the rosacea market in the UK. Described as a `treatment cream for Rosacea and Couperose’ Dermalex seems to be a mild and reasonably priced skincare cream. The product publicity includes the following grand sounding claims’ The patented Tri-solve® […]

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ONRELTEA User Reviews

Galderma, for reasons unknown, decided to rebrand the newly FDA approved Mirvaso as ONRELTEA in Canada (yes they use all capitals in the brand name). This continues the tradition for Galderma of split North American branding; Oracea in the US is known as Efracea in Canada. There is already some history of user experiences of […]

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Skinceuticals Redness Neutralizer can help a red face

First hinted at 2 years ago at the 2012 AAD meeting in San Diego, a new topical from Skinceuticals is now available and is starting to accumulate some modest research suggesting that it is good for a red face. This paper published in the JDD suggests that using Skinceuticals Redness Neutralizer along with the regular […]

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Moisturizers

Soolantra Cream is based on Cetaphil Moisturizing Cream

In the media materials released when Soolantra was announced, Galderma told us that Soolantra is based on their Cetaphil Moisturizing Cream. Soolantra Media Release Soolantra (ivermectin) Cream, 1% is a new, antibiotic-free, prescription topical treatment for the bumps and pimples of rosacea. Soolantra Cream may provide visible results as early as week two. Cetaphil Moisturizing […]

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NeoStrata Facial Cleanser and Ultra Moisturizing Face Cream

Rosacea sufferers are always on the lookup for suitable cleansers and moisturizers. One of the pearls in finding relief from rosacea symptoms is that finding a supporting and gentle cleansing and moisturizing (and protective) regime is important. A recent paper by Dr. Patricia Farris, Skin Care Based on Science: Improving Outcomes in Rosacea, tells us […]

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Bionect improves Rosacea Symptoms

A recent paper in the Journal of Drugs in Dermatology suggests that Bionect may be helpful for the symptoms of rosacea. The study found that after 4 weeks the burning or stinging and dryness of rosacea was much improved, while papules and redness were also improved. What is Bionect? Bionect is a prescription only cream, […]

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The American Academy of Dermatology has published some face-washing tips. Washing your face may seem like such a simple activity that highlighting it may feel unnecessary. For rosacea sufferers though, we know that a gentle skin care regime is important. Starting your rosacea-beating regime with an irritating cleanse is simply going to make your skin […]

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Cleansers

Cetaphil Gentle Skin Cleansing Wipes, no rinsing needed

I feel like a bit of a Galderma PR machine at the moment, but Galderma do seem to be doing a lot. Maybe this product is yet another step in Galderma’s quest  to own the Rosacea Market. So coming soon is a moist cloth version of Cetaphil Gentle Skin Cleanser. Have you ever wished that […]

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NeoStrata Facial Cleanser and Ultra Moisturizing Face Cream

Rosacea sufferers are always on the lookup for suitable cleansers and moisturizers. One of the pearls in finding relief from rosacea symptoms is that finding a supporting and gentle cleansing and moisturizing (and protective) regime is important. A recent paper by Dr. Patricia Farris, Skin Care Based on Science: Improving Outcomes in Rosacea, tells us […]

Continue Reading

Syndets and Lipid Free Cleansers, What Are They? Do They Work?

You may have come across the term Syndet or `Lipid Free Cleanser’ when researching mild cleansers. What are they, and am I missing something by not having them in my daily regime? What is a Syndet? Well the term means `Synthetic Detergent’ and is an attempt to create a cleanser that is suitable for the […]

Continue Reading

The American Academy of Dermatology has published some face-washing tips. Washing your face may seem like such a simple activity that highlighting it may feel unnecessary. For rosacea sufferers though, we know that a gentle skin care regime is important. Starting your rosacea-beating regime with an irritating cleanse is simply going to make your skin […]

Continue Reading

New Treatments

Promius Pharma, a subsidiary of Dr. Reddy’s Laboratory has filed a New Drug Application for a modified release tetracycline for the treatment of rosacea. Promius is calling their new drug DFD-09. Promius Pharma is probably best know to rosacea sufferers via the availability of Promiseb Topical Cream in the US. Promiseb, a treatment for seborrheic […]

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How does Soolantra (topical ivermectin) work?

Ahead of the expected approval and launch of Galderma’s Ivermectin 1% Cream is this abstract further highlighting the credentials of topical ivermectin. How does Ivermectin exhibit superior papule and pustule clearing abilities ? Well this paper tells us that topical ivermectin is effective because of its antimicrobial, antiparasitic, antibacterial, and anti-inflammatory activities. Galderma is expected […]

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Actavis to trial Mirvaso competitor

An interesting development in rosacea clinical trials is the emergence of a new company called Actavis. Actavis have listed a large trial where they plan to test their Brimonidine Gel against Galderma’s recently FDA approved Brimonidine-based Mirvaso Gel. The large Phase 3 trial will compare the response after 7 days. Up to 462 patients in […]

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Gladskin Rosacea Cream and Gel, Staphefekt in a topical

Seeking to create products based on the recently publicised MRSA-killing topical Staphefekt are some topical creams to treat rosacea, acne, eczema and general skin irritation.

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