January 13th, 2006, by Digital Davo | tetracyclines
This paper discusses strategies to reduce antibiotic exposure during rosacea therapy; including using combination therapy with oral antibiotics and topical therapies/agents. This could be used as maintenance therapy for longer term benefits. Note that the use of low dose doxycycline like Oracea is also another option when thinking about possible antibiotic resistance issues.
Preventing antibiotic resistance in the treatment of rosacea, Family Practice …
January 12th, 2006, by Digital Davo | tetracyclines
Effects of minocycline on the ocular flora of patients with acne rosacea or seborrheic blepharitis.Cornea. 2003 Aug;22(6):545-8.Ta CN, Shine WE, McCulley JP, Pandya A, Trattler W, Norbury JW.Department of Ophthalmology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.PURPOSE: To assess the effect of minocycline on the ocular flora in patients …
November 10th, 2005, by Digital Davo | tetracyclines
Formerly known as COL-3, Incyclinide is a chemically modified tetracycline, modified to retain non-antibiotic properties that may make them effective in treating diseases involving inflammation and/or destruction of the body’s connective tissues.
CollaGenex have announced that the National Institutes of Health (”NIH”) has awarded a grant of approximately $962,000 for additional research into the potent anti-inflammatory effects of incyclinide.
The grant will be paid over two …
November 1st, 2005, by Digital Davo | metrogel, tetracyclines
Yes another one of those `antibiotics + metrogel is all you need’ sort of article. This paper does at least show that low dose doxycycline is gaining weight in the research listings though. Also note that Collagenex naturally has an interest in this sort of published research as they are promoting their periostat and oracea products.
A randomized, double-blind, placebo-controlled trial of the combined effect of …
September 27th, 2005, by Digital Davo | tetracyclines
Formerly known as COL-3, Incyclinide will start a new Phase 2, double-blinded, placebo-controlled trial to find the best treatment dose. This trial will evaluate 300 patients for moderate to severe acne. A recent Phase 2 Clinical Trial showed some promise for inflammatory lesions in rosacea.
Incyclinide is a chemically modified tetracycline, modified to retain non-antibiotic properties that may make them effective in treating diseases involving …
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