rosacea cause articles ↓

Lots of buzz at the moment about the publicity raised by a nature.com article about Cathelicidins. Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea Acne rosacea is an inflammatory skin disease that affects 3% of the US population over 30 years of age and is characterized by erythema, papulopustules and telangiectasia. The etiology of this disorder is unknown, …

I have mentioned a few times in the past that the way that metrogel helps rosacea is unknown. This statement deserves some clarification. Actually the way that metronidazole works is well known. How the effect of metrogel leads to a benefit in rosacea, well, that is something worth exploring some more later on. You may wonder why there is so much emphasis on the metronidazole based products …

A really interesting thread is going on in the rosacea-support group. Dan is airing some of his thoughts on how a pathogen might lead to the chronic inflammation we see in rosacea. Even though Dan clearly states he has no medical background (and indeed it is worth remembering this point) it is clear that he has done a lot of reading on this topic.

Message …

This study shows that one of the effects of azithromycin is to suppress reactive oxygen species, one of the chemicals involved in the inflammatory pathway. Other systemic antibiotics, macrolides and non-antibiotic doses of doxycycline have also been shown to be helpful in treating the inflammation of rosacea.

The inflammatory pathway that leads to rosacea is an interesting area that is attracting more and more interest and research. Note here …

The NRS Blog has a new entry highlighting the Dark Side of ATP. This doesn’t appear to be newly published information, but a chance to highlight the possible role of adenosine 5′-triphosphate (ATP) in the inflammatory pathways that lead to rosacea. The key to improving therapy is to identify those inflammatory pathways involved with rosacea so they can be better controlled.” … …