macrolides articles ↓
May 27th, 2008, by David Pascoe | macrolides, topicals
This paper details a somewhat exotic combination therapy: oral azithromycin and topical tacrolimus. It offers an alternative to the more common doxycycline + metrogel combination. The authors mention that this is not a first line therapy; "a combination of oral azithromycin and …
January 8th, 2008, by David Pascoe | accutane, macrolides, papules & pustules, steroids
One often asked question by newly diagnosed sufferers is `can you get rosacea on areas other than your face’. The usual answer is no; you normally only see rosacea symptoms on the flushing zone areas in the central areas of your face. This paper slightly dispels this idea with a case report about one patient …
April 3rd, 2007, by David Pascoe | macrolides
As a followup to the recent note pathogen infection (Chlamydia pneumoniae) cause theory, comes a recently published paper, the first to address Cpn and Rosacea. This paper is very preliminary, but at least now Cpn is on the map. When a paper ends with “preliminary data suggest the need for further investigation” it means that the research can still go in any direction – confirming, negating or …
January 31st, 2007, by David Pascoe | macrolides, rosacea cause
This study shows that one of the effects of azithromycin is to suppress reactive oxygen species, one of the chemicals involved in the inflammatory pathway. Other systemic antibiotics, macrolides and non-antibiotic doses of doxycycline have also been shown to be helpful in treating the inflammation of rosacea.
The inflammatory pathway that leads to rosacea is an interesting area that is attracting more and more interest and research. Note here …
September 28th, 2006, by David Pascoe | fact sheets, macrolides
Macrolide Antibiotics offer alternative treatment options to the well known tetracycline antibiotics. In recent years good studies have shown that some of these macrolides are safe and effective in treating rosacea.
Commonly prescribed Macrolides include: erythromycin, azithromycin (Zithromax), clarithromycin (Biaxin), dirithromycin (Dynabac), roxithromycin (Rulid, Surlid)
Here is a brief introduction from Linda Sy’s `Skin411 Digest January 2005′, Summaries and commentaries from recent dermatologic …