doxycycline articles ↓

Doxycycline is a broad spectrum antibiotic that chelates metal ions and is frequently used as part of treatment of ocular surface diseases. Its therapeutic value has been attributed to an ability to inhibit matrix metalloproteinase activity and both matrix metalloproteinase and interleukin-1 synthesis. Smith and Cook studied corneal epithelial cell and keratocyte cultures and in this study they demonstrated that the minimum concentration of doxycycline …

Some more background about subantimicrobial (sometimes referred to as SD - Subantimicrobial Dosage) doxycycline and rosacea. A dosage of around 50mg per day is enough to see a benefit in rosacea symptoms but also low enough to not affect gut flora or cause other antibiotic related side effects. SD doxycycline can also be take safely for longer periods of time compared to higher doses …

Given the recent developments in periostat, oracea and COL-3 an interesting article about the applicability of low dose doxycycline. The term SDD refers to `subantimicrobial dose doxycycline hyclate’.

From US Pharmacist, Vol. No: 29:04 Posted: 4/15/04.

New Applications of Doxycycline Hyclate in Medicine and Dentistry
Golub and his colleagues were able to show that tetracycline exerted a unique property that was independent of its antimicrobial …

Periostat (20 mgs doxycycline hyclate) has been helpful to some rosacea sufferers. Originally developed to combat periodontal disease (gum disease), periostat was approved by the FDA in 1998. Recently the FDA approved the introduction of generic periostat equivalents.

Ivax Pharmaceuticals and CorePharma are now free to sell their generic equivalents of Periostat.

Oracea contains doxycycline, the same active ingredient as CollaGenex’s gum disease …