doxycycline articles ↓

Collagenex is reporting today that Oracea is equally effective as 100mg of doxycycline. This latest press release is a culmination of a trial that we have reported previously - oracea plus metrogel, better than 100mg doxycycline plus metrogel ? and also a 2007 SkinMed paper; maximum effective dose of doxycycline is 40mg a day. The main point of the trial was …

Thanks for the tip from Ben. A clinical trial listed for treating both facial and ocular rosacea with Oracea suggests that Oracea might soon be marketed directly as an ocular rosacea treatment. This phase 2 trial’s purpose is to determine the safety and efficacy of sub-antimicrobial dose doxycycline in the treatment of patients who have both blepharitis and facial rosacea. The trial …

There has been a lot of copy written about so-called low dose or anti-inflammatory dose doxycycline. This form of antibiotic therapy is one of the more promising recent therapeutic developments ; it will likely become a widely known and available treatment. This recently published paper shows that a daily dose of 40mg of doxycycline is as effective in reducing the lesions of rosacea as …

A clinical trial, sponsored by CollaGenex, is recruiting patients to see how Oracea compares to doxycycline (100mg once a day) when combined with metrogel 1%. We can see from a Collagenex annual report that COL-101 was the name for Periostat MR, which then became Oracea. Safety and Efficacy Study to Compare Two Rosacea Treatment Regimens Purpose: To compare the safety and efficacy of two treatment …

Another paper confirming the importance of MMP and the inflammation found in ocular and facial rosacea. This follows up on another recent article suggesting that a diagnostic test for ocular rosacea could be based on the “high abundance of oligosaccharides in the tear fluid of patients with ocular rosacea”. MMPs have also been shown as important in the inflammatory pathway in other studies, see …